Transcriptional profiling of a fungal granuloma reveals a low metabolic activity of Paracoccidioides brasiliensis yeasts and an actively regulated host immune response (2023)
- Authors:
- Borges, Bruno Montanari
- Ramos, Rafael Berton Correia
- Preite, Nycolas Willian
- Kaminski, Valéria de Lima
- Camacho, Maurício
- Campos, Claudia Barbosa Ladeira de
- Zelanis, André
- Loures, Flavio Vieira
- Castro, Patrícia Alves de
- Maximo, Marina Ferreira
- Fill, Taicia Pacheco
- Traynor, Aimee M.
- Özlem Sarikaya-Bayram
- Sean Doyle
- Bayram, Özgür
- Goldman, Gustavo Henrique
- Calich, Vera Lúcia Garcia
- Borges, Bruno Montanari
- USP affiliated authors: GOLDMAN, GUSTAVO HENRIQUE - FCFRP ; CALICH, VERA LUCIA GARCIA - ICB
- Unidades: FCFRP; ICB
- DOI: 10.3389/fcimb.2023.1268959
- Subjects: IMUNOLOGIA; GRANULOMA; PARACOCCIDIOIDOMICOSE; PARACOCCIDIOIDES; PROTEÔMICA; FERRO; CAMUNDONGOS ENDOGÂMICOS C57BL; TRANSCRIÇÃO GÊNICA
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Publisher: Frontiers Research Foundation
- Publisher place: Lausanne
- Date published: 2023
- Source:
- Título: Frontiers in Cellular and Infection Microbiology
- ISSN: 2235-2988
- Volume/Número/Paginação/Ano: v. 13, art. 1268959, 27 p., 2023
- Este periódico é de acesso aberto
- Este artigo NÃO é de acesso aberto
-
ABNT
BORGES, Bruno Montanari et al. Transcriptional profiling of a fungal granuloma reveals a low metabolic activity of Paracoccidioides brasiliensis yeasts and an actively regulated host immune response. Frontiers in Cellular and Infection Microbiology, v. 13, p. 27 , 2023Tradução . . Disponível em: https://doi/org/10.3389/fcimb.2023.1268959. Acesso em: 04 mar. 2026. -
APA
Borges, B. M., Ramos, R. B. C., Preite, N. W., Kaminski, V. de L., Camacho, M., Campos, C. B. L. de, et al. (2023). Transcriptional profiling of a fungal granuloma reveals a low metabolic activity of Paracoccidioides brasiliensis yeasts and an actively regulated host immune response. Frontiers in Cellular and Infection Microbiology, 13, 27 . doi:10.3389/fcimb.2023.1268959 -
NLM
Borges BM, Ramos RBC, Preite NW, Kaminski V de L, Camacho M, Campos CBL de, Zelanis A, Loures FV, Castro PA de, Maximo MF, Fill TP, Traynor AM, Özlem Sarikaya-Bayram, Sean Doyle, Bayram Ö, Goldman GH, Calich VLG. Transcriptional profiling of a fungal granuloma reveals a low metabolic activity of Paracoccidioides brasiliensis yeasts and an actively regulated host immune response [Internet]. Frontiers in Cellular and Infection Microbiology. 2023 ; 13 27 .[citado 2026 mar. 04 ] Available from: https://doi/org/10.3389/fcimb.2023.1268959 -
Vancouver
Borges BM, Ramos RBC, Preite NW, Kaminski V de L, Camacho M, Campos CBL de, Zelanis A, Loures FV, Castro PA de, Maximo MF, Fill TP, Traynor AM, Özlem Sarikaya-Bayram, Sean Doyle, Bayram Ö, Goldman GH, Calich VLG. Transcriptional profiling of a fungal granuloma reveals a low metabolic activity of Paracoccidioides brasiliensis yeasts and an actively regulated host immune response [Internet]. Frontiers in Cellular and Infection Microbiology. 2023 ; 13 27 .[citado 2026 mar. 04 ] Available from: https://doi/org/10.3389/fcimb.2023.1268959 - cd28 costimulatory molecule deficiency in more severe paracoccidioides brasiliensis infection but protects mice from life-threatening immunopathology
- Paracoccidioides brasiliensis infection determines dentric cells to diferentiate to the plasmacytoid subpopulation which induces a more severe pulmonary infection when transfered to resistant mice
- The IDO-AhR axis controls Th17/Treg immunity in a pulmonary model of fungal infection
- TLR-2 is a negative regulator of TH17 cells and tissue pathology in a pulmonary model of fungal infection
- Absence of TLR2 results in less severe paracoccidioidomycosis but increased inflammatory response caused by PMN & TH17 cells
- Toll like receptors and the adaptor molecule MYD88 play an important role in pulmonary paracoccidioidomycosis
- TLR2 is a negative regulator of Th17 cells and tissue pathology in a pulmonary model of fungal infection
- Human alfa / beta and gama / delta t cells respond to proteins of the yeast form of paracoccidioides brasiliensis
- The immune response of high (H) and low responders (L) mice (selection III) and F1 (HIII x LIII) hybrids to paracoccidioides brasiliensis infection
- PMN leukocytes play a more prominent role in natural immunity of susceptible than resistant mice to pulmonary paracoccidiodomycosis
Informações sobre o DOI: 10.3389/fcimb.2023.1268959 (Fonte: oaDOI API)
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