Artigo de periodico

Influence of titanium nanotubular surfaces, produced by anodization, on the behavior of osteogenic cells: in vitro evaluation (2022)

• Authors:
  • Araujo, Juliani Caroline Ribeiro de
  • Espírito Santo, Lidiane Lopes do
  • Schneider, Sandra Giacomin
  • Melo, Gabriela de Fatima Santana
  • Chaves, Isabel
  • Franzini, Denise Richter
  • Spalding, Marianne
  • Vasconcellos, Luana Marotta Reis de
• Autor USP: SCHNEIDER, SANDRA GIACOMIN - EEL
• Unidade: EEL
• DOI: 10.4322/bds.2022.e2528
• Subjects: Nanotopografia; OSTEOBLASTO; IMPLANTES DENTÁRIOS
• Keywords: Implantes de titânio; Titanium implants; Nanotopography; Osteoblast; Titanium alloy; Liga de titânio
• Agências de fomento:
  • Financiamento CAPES
• Language: Inglês
• Abstract: The objective of this study was to evaluate in vitro the influence of the anodized surface of Ti35Nb7Zr alloy on the behavior of osteogenic cells, for future application in biomedical implants. Material and Methods:For the development of this research, samples of commercially pure titanium (TiCp) and samples of Ti35Nb7Zr alloy were anodized, both were characterized by scanning electron microscopy (SEM) and were plated afterwards with human osteoblast-like cells (MG63 line) (2 x 104). Cell adhesion, cytotoxicity test, formation of mineralization nodules and a comet assay were also performed in different periods. The bottom of the plate was used as a control, without a sample. Results: SEM analysis showed that the topography of both samples presented surfaces covered by nanotubes. Cellular morphology exhibited spreading in both samples proposing an intimate cell-material liaison. After 3 days, the Ti35Nb7Zr group exhibited greater cell viability than the TiCp group (p<0.01). Regarding calcium content, there was no statistical difference between the anodized groups, but there was a difference between the experimental groups and the control group (p<0.01). In the comet assay, the percentage of DNA in the comet tail did not exhibit any significant difference (p>0.05) among the groups in the evaluated periods. Conclusion: It was concluded that this process of anodization was efficient to form nanotubes, as well as promote a positive influence on the behavior of osteogenic cells without promoting cell damage.
• Imprenta:
  • Publisher place: São José dos Campos-SP
  • Date published: 2022
• Source:
  • Título: Brazilian dental science
  • ISSN: 21786011
  • Volume/Número/Paginação/Ano: v.25, n.1, p.1-9, 2022

Informações sobre o DOI: 10.4322/bds.2022.e2528 (Fonte: oaDOI API)
• Este periódico é de acesso aberto
• Este artigo é de acesso aberto
• URL de acesso aberto
• Cor do Acesso Aberto: gold
• Licença: cc-by

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How to cite

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• ABNT

  ARAUJO, Juliani Caroline Ribeiro de et al. Influence of titanium nanotubular surfaces, produced by anodization, on the behavior of osteogenic cells: in vitro evaluation. Brazilian dental science, v. 25, n. 1, p. 1-9, 2022Tradução . . Disponível em: https://doi.org/10.4322/bds.2022.e2528. Acesso em: 31 dez. 2025.

• APA

  Araujo, J. C. R. de, Espírito Santo, L. L. do, Schneider, S. G., Melo, G. de F. S., Chaves, I., Franzini, D. R., et al. (2022). Influence of titanium nanotubular surfaces, produced by anodization, on the behavior of osteogenic cells: in vitro evaluation. Brazilian dental science, 25( 1), 1-9. doi:10.4322/bds.2022.e2528

• NLM

  Araujo JCR de, Espírito Santo LL do, Schneider SG, Melo G de FS, Chaves I, Franzini DR, Spalding M, Vasconcellos LMR de. Influence of titanium nanotubular surfaces, produced by anodization, on the behavior of osteogenic cells: in vitro evaluation [Internet]. Brazilian dental science. 2022 ;25( 1): 1-9.[citado 2025 dez. 31 ] Available from: https://doi.org/10.4322/bds.2022.e2528

• Vancouver

  Araujo JCR de, Espírito Santo LL do, Schneider SG, Melo G de FS, Chaves I, Franzini DR, Spalding M, Vasconcellos LMR de. Influence of titanium nanotubular surfaces, produced by anodization, on the behavior of osteogenic cells: in vitro evaluation [Internet]. Brazilian dental science. 2022 ;25( 1): 1-9.[citado 2025 dez. 31 ] Available from: https://doi.org/10.4322/bds.2022.e2528

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