2-aminobenzimidazoles for leishmaniasis: from initial hit discovery to in vivo profiling (2021)
- Authors:
- Ferreira, Rafael Augusto Alves
- Rezende Junior, Celso de

- Martinez, Pablo David Grigol

- Koovits, Paul John

- Soares, Bruna Miranda

- Ferreira, Leonardo Luiz Gomes

- Duarte, Simone Michelan

- Chelucci, Rafael Consolin
- Andricopulo, Adriano Defini

- Galuppo, Mariana Kolos

- Uliana, Silvia Reni Bortolin

- Matheeussen, An

- Caljon, Guy

- Maes, Louis

- Campbell, Simon
- Kratz, Jadel M.

- Mowbray, Charles E.

- Dias, Luiz Carlos
- USP affiliated authors: DUARTE, SIMONE MICHELAN - IFSC ; ANDRICOPULO, ADRIANO DEFINI - IFSC ; ULIANA, SILVIA RENI BORTOLIN - ICB ; FERREIRA, LEONARDO LUIZ GOMES - IFSC ; CHELUCCI, RAFAEL CONSOLIN - IFSC ; GALUPPO, MARIANA KOLOS - ICB
- Unidades: IFSC; ICB
- DOI: 10.1371/journal.pntd.0009196
- Subjects: ANTIPARASITÁRIOS; LEISHMANIA INFANTUM; PLANEJAMENTO DE FÁRMACOS; PARASITOLOGIA; MODELOS ANIMAIS DE DOENÇAS; CAMUNDONGOS; TOXICIDADE EM ANIMAL
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Publisher place: San Francisco
- Date published: 2021
- Source:
- Título: PLOS Neglected Tropical Diseases
- ISSN: 1935-2735
- Volume/Número/Paginação/Ano: v. 15, n. 2, p. e0009196-1-e0009196-20, Feb. 2021
- Este periódico é de acesso aberto
- Este artigo NÃO é de acesso aberto
-
ABNT
FERREIRA, Rafael Augusto Alves et al. 2-aminobenzimidazoles for leishmaniasis: from initial hit discovery to in vivo profiling. PLOS Neglected Tropical Diseases, v. 15, n. 2, p. e0009196-1-e0009196-20, 2021Tradução . . Disponível em: https://doi.org/10.1371/journal.pntd.0009196. Acesso em: 25 fev. 2026. -
APA
Ferreira, R. A. A., Rezende Junior, C. de, Martinez, P. D. G., Koovits, P. J., Soares, B. M., Ferreira, L. L. G., et al. (2021). 2-aminobenzimidazoles for leishmaniasis: from initial hit discovery to in vivo profiling. PLOS Neglected Tropical Diseases, 15( 2), e0009196-1-e0009196-20. doi:10.1371/journal.pntd.0009196 -
NLM
Ferreira RAA, Rezende Junior C de, Martinez PDG, Koovits PJ, Soares BM, Ferreira LLG, Duarte SM, Chelucci RC, Andricopulo AD, Galuppo MK, Uliana SRB, Matheeussen A, Caljon G, Maes L, Campbell S, Kratz JM, Mowbray CE, Dias LC. 2-aminobenzimidazoles for leishmaniasis: from initial hit discovery to in vivo profiling [Internet]. PLOS Neglected Tropical Diseases. 2021 ; 15( 2): e0009196-1-e0009196-20.[citado 2026 fev. 25 ] Available from: https://doi.org/10.1371/journal.pntd.0009196 -
Vancouver
Ferreira RAA, Rezende Junior C de, Martinez PDG, Koovits PJ, Soares BM, Ferreira LLG, Duarte SM, Chelucci RC, Andricopulo AD, Galuppo MK, Uliana SRB, Matheeussen A, Caljon G, Maes L, Campbell S, Kratz JM, Mowbray CE, Dias LC. 2-aminobenzimidazoles for leishmaniasis: from initial hit discovery to in vivo profiling [Internet]. PLOS Neglected Tropical Diseases. 2021 ; 15( 2): e0009196-1-e0009196-20.[citado 2026 fev. 25 ] Available from: https://doi.org/10.1371/journal.pntd.0009196 - Hit-to-lead optimization of a 2-aminobenzimidazole series as new candidates for chagas disease
- Discovery of arylpiperazines with broad-spectrum antimicrobial activity and favorable pharmacokinetic profiles
- Evaluation and discovery of novel benzothiazole derivatives as promising hits against Leishmania infantum
- Optimized HDAC inhibitors induce robust γ-globin gene expression and exhibit superior efficacy to hydroxyurea in Sickle Cell Disease models
- Novel deferasirox analogues designed as iron chelating agents for iron overload treatment
- Hit-to-lead optimization of a benzene sulfonamide series for potential antileishmanial agents
- Indoles hit-to-lead for chagas disease: lessons learned within the LOLA consortium
- Convergent synthesis of proline-functionalized pyrazolopyrimidines as anti-T. cruzi bioactive compounds
- Design, synthesis and in vitro evaluation of a series of arylmorpholine derivative compounds against chagas disease
- Design and synthesis of boronic chalcones with dual anticancer and anti-inflammatory activity
Informações sobre o DOI: 10.1371/journal.pntd.0009196 (Fonte: oaDOI API)
Download do texto completo
| Tipo | Nome | Link | |
|---|---|---|---|
| 3022720.pdf | Direct link |
How to cite
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
