Artigo de periodico

Hit-to-lead optimization of a 2-aminobenzimidazole series as new candidates for chagas disease (2023)

• Authors:
  • Rezende Junior, Celso de Oliveira
  • Martinez, Pablo David Grigol
  • Ferreira, Rafael Augusto Alves
  • Koovits, Paul John
  • Soares, Bruna Miranda
  • Ferreira, Leonardo Luiz Gomes
  • Duarte, Simone Michelan
  • Chelucci, Rafael Consolin
  • Andricopulo, Adriano Defini
  • Matheeussen, An
  • Van Pelt, Natascha
  • Caljon, Guy
  • Maes, Louis
  • Campbell, Simon
  • Kratz, Jadel Muller
  • Mowbray, Charles E.
  • Dias, Luiz Carlos
• USP affiliated authors: FERREIRA, LEONARDO LUIZ GOMES - IFSC ; ANDRICOPULO, ADRIANO DEFINI - IFSC ; DUARTE, SIMONE MICHELAN - IFSC ; CHELUCCI, RAFAEL CONSOLIN - IFSC
• Unidade: IFSC
• DOI: 10.1016/j.ejmech.2022.114925
• Subjects: DOENÇA DE CHAGAS; PLANEJAMENTO DE FÁRMACOS; TRYPANOSOMA CRUZI
• Keywords: 2-Aminobenzimidazole derivatives; Chagas disease; Hit-to-lead; Multiparametric optimization; Trypanosoma cruzi
• Agências de fomento:
  • Financiamento FAPESP
  • Financiamento CNPq
• Language: Inglês
• Imprenta:
  • Publisher place: Issy-les-Moulineaux
  • Date published: 2023
• Source:
  • Título: European Journal of Medicinal Chemistry
  • ISSN: 0223-5234
  • Volume/Número/Paginação/Ano: v. 246, p. 114925-1-114925-10 + supplementary data, Jan. 2023

Informações sobre o DOI: 10.1016/j.ejmech.2022.114925 (Fonte: oaDOI API)
• Este periódico é de assinatura
• Este artigo é de acesso aberto
• URL de acesso aberto
• Cor do Acesso Aberto: hybrid
• Licença: cc-by

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• ABNT

  REZENDE JUNIOR, Celso de Oliveira et al. Hit-to-lead optimization of a 2-aminobenzimidazole series as new candidates for chagas disease. European Journal of Medicinal Chemistry, v. 246, n. Ja 2023, p. 114925-1-114925-10 + supplementary data, 2023Tradução . . Disponível em: https://doi.org/10.1016/j.ejmech.2022.114925. Acesso em: 24 dez. 2025.

• APA

  Rezende Junior, C. de O., Martinez, P. D. G., Ferreira, R. A. A., Koovits, P. J., Soares, B. M., Ferreira, L. L. G., et al. (2023). Hit-to-lead optimization of a 2-aminobenzimidazole series as new candidates for chagas disease. European Journal of Medicinal Chemistry, 246( Ja 2023), 114925-1-114925-10 + supplementary data. doi:10.1016/j.ejmech.2022.114925

• NLM

  Rezende Junior C de O, Martinez PDG, Ferreira RAA, Koovits PJ, Soares BM, Ferreira LLG, Duarte SM, Chelucci RC, Andricopulo AD, Matheeussen A, Van Pelt N, Caljon G, Maes L, Campbell S, Kratz JM, Mowbray CE, Dias LC. Hit-to-lead optimization of a 2-aminobenzimidazole series as new candidates for chagas disease [Internet]. European Journal of Medicinal Chemistry. 2023 ; 246( Ja 2023): 114925-1-114925-10 + supplementary data.[citado 2025 dez. 24 ] Available from: https://doi.org/10.1016/j.ejmech.2022.114925

• Vancouver

  Rezende Junior C de O, Martinez PDG, Ferreira RAA, Koovits PJ, Soares BM, Ferreira LLG, Duarte SM, Chelucci RC, Andricopulo AD, Matheeussen A, Van Pelt N, Caljon G, Maes L, Campbell S, Kratz JM, Mowbray CE, Dias LC. Hit-to-lead optimization of a 2-aminobenzimidazole series as new candidates for chagas disease [Internet]. European Journal of Medicinal Chemistry. 2023 ; 246( Ja 2023): 114925-1-114925-10 + supplementary data.[citado 2025 dez. 24 ] Available from: https://doi.org/10.1016/j.ejmech.2022.114925

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