Hit-to-Lead optimization of pyridylpiperazine derivatives: promising antimalarial candidates with notable ADME profiles and metabolic stability (2025)
- Authors:
- USP affiliated authors: FERREIRA, LEONARDO LUIZ GOMES - IFSC ; ANDRICOPULO, ADRIANO DEFINI - IFSC ; WUNDERLICH, GERHARD - ICB ; KRÜGER, ARNE - ICB ; CHELUCCI, RAFAEL CONSOLIN - IFSC
- Unidades: IFSC; ICB
- Subjects: MALÁRIA; PLASMODIUM FALCIPARUM; PLANEJAMENTO DE FÁRMACOS
- Keywords: ADME properties; In vivo assay; Plasmodium falciparum; Malaria
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Publisher: Sociedade Brasileira de Química - SBQ
- Publisher place: São Paulo
- Date published: 2025
- Source:
- Título: Anais
- Conference titles: Reunião Anual da Sociedade Brasileira de Química - RASBQ
-
ABNT
OLIVEIRA, Douglas Davison da Silva et al. Hit-to-Lead optimization of pyridylpiperazine derivatives: promising antimalarial candidates with notable ADME profiles and metabolic stability. 2025, Anais.. São Paulo: Sociedade Brasileira de Química - SBQ, 2025. Disponível em: https://repositorio.usp.br/directbitstream/f179559b-b0ab-49da-8d2d-69b170cab755/3259728.pdf. Acesso em: 04 ago. 2025. -
APA
Oliveira, D. D. da S., Krüger, A., Chelucci, R. C., Ferreira, L. L. G., Andricopulo, A. D., Wunderlich, G., et al. (2025). Hit-to-Lead optimization of pyridylpiperazine derivatives: promising antimalarial candidates with notable ADME profiles and metabolic stability. In Anais. São Paulo: Sociedade Brasileira de Química - SBQ. Recuperado de https://repositorio.usp.br/directbitstream/f179559b-b0ab-49da-8d2d-69b170cab755/3259728.pdf -
NLM
Oliveira DD da S, Krüger A, Chelucci RC, Ferreira LLG, Andricopulo AD, Wunderlich G, Silva NM da, Rezende Junior C de O. Hit-to-Lead optimization of pyridylpiperazine derivatives: promising antimalarial candidates with notable ADME profiles and metabolic stability [Internet]. Anais. 2025 ;[citado 2025 ago. 04 ] Available from: https://repositorio.usp.br/directbitstream/f179559b-b0ab-49da-8d2d-69b170cab755/3259728.pdf -
Vancouver
Oliveira DD da S, Krüger A, Chelucci RC, Ferreira LLG, Andricopulo AD, Wunderlich G, Silva NM da, Rezende Junior C de O. Hit-to-Lead optimization of pyridylpiperazine derivatives: promising antimalarial candidates with notable ADME profiles and metabolic stability [Internet]. Anais. 2025 ;[citado 2025 ago. 04 ] Available from: https://repositorio.usp.br/directbitstream/f179559b-b0ab-49da-8d2d-69b170cab755/3259728.pdf - Design, synthesis and in vitro evaluation of a series of arylmorpholine derivative compounds against chagas disease
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