Chalcones from Angelica keiskei (ashitaba) inhibit key Zika virus replication proteins (2022)
- Authors:
- Mottin, Melina
- Caesar, Lindsay K.
- Brodsky, David
- Mesquita, Nathalya Cristina de Moraes Roso
- Oliveira, Ketllyn Irene Zagato de
- Noske, Gabriela Dias
- Sousa, Bruna K. P.
- Ramos, Paulo R. P. S.
- Jarmer, Hannah
- Loh, Bonnie
- Zorn, Kimberley M.
- Foil, Daniel H.
- Torres, Pedro M.
- Guido, Rafael Victorio Carvalho

- Oliva, Glaucius

- Scholle, Frank
- Ekins, Sean
- Cech, Nadja B.
- Andrade, Carolina Horta
- Laster, Scott M.
- USP affiliated authors: GUIDO, RAFAEL VICTÓRIO CARVALHO - IFSC ; OLIVA, GLAUCIUS - IFSC ; MESQUITA, NATHALYA CRISTINA DE MORAES ROSO - IFSC ; OLIVEIRA, KETLLYN IRENE ZAGATO DE - IFSC
- Unidade: IFSC
- DOI: 10.1016/j.bioorg.2022.105649
- Subjects: ZIKA VÍRUS; PRODUTOS NATURAIS; FLAVIVIRIDAE; ENZIMAS; PROTEÍNAS; FARMACOLOGIA
- Keywords: Angelica keiskei; Ashitaba; Chalcones; Zika virus; Polymerase; Protease
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Source:
- Título: Bioorganic Chemistry
- ISSN: 0045-2068
- Volume/Número/Paginação/Ano: v. 120, p. 105649-1-105649-12 + supplementary data: 1-13, Mar. 2022
- Este periódico é de acesso aberto
- Este artigo NÃO é de acesso aberto
-
ABNT
MOTTIN, Melina et al. Chalcones from Angelica keiskei (ashitaba) inhibit key Zika virus replication proteins. Bioorganic Chemistry, v. 120, p. 105649-1-105649-12 + supplementary data: 1-13, 2022Tradução . . Disponível em: https://doi.org/10.1016/j.bioorg.2022.105649. Acesso em: 12 fev. 2026. -
APA
Mottin, M., Caesar, L. K., Brodsky, D., Mesquita, N. C. de M. R., Oliveira, K. I. Z. de, Noske, G. D., et al. (2022). Chalcones from Angelica keiskei (ashitaba) inhibit key Zika virus replication proteins. Bioorganic Chemistry, 120, 105649-1-105649-12 + supplementary data: 1-13. doi:10.1016/j.bioorg.2022.105649 -
NLM
Mottin M, Caesar LK, Brodsky D, Mesquita NC de MR, Oliveira KIZ de, Noske GD, Sousa BKP, Ramos PRPS, Jarmer H, Loh B, Zorn KM, Foil DH, Torres PM, Guido RVC, Oliva G, Scholle F, Ekins S, Cech NB, Andrade CH, Laster SM. Chalcones from Angelica keiskei (ashitaba) inhibit key Zika virus replication proteins [Internet]. Bioorganic Chemistry. 2022 ; 120 105649-1-105649-12 + supplementary data: 1-13.[citado 2026 fev. 12 ] Available from: https://doi.org/10.1016/j.bioorg.2022.105649 -
Vancouver
Mottin M, Caesar LK, Brodsky D, Mesquita NC de MR, Oliveira KIZ de, Noske GD, Sousa BKP, Ramos PRPS, Jarmer H, Loh B, Zorn KM, Foil DH, Torres PM, Guido RVC, Oliva G, Scholle F, Ekins S, Cech NB, Andrade CH, Laster SM. Chalcones from Angelica keiskei (ashitaba) inhibit key Zika virus replication proteins [Internet]. Bioorganic Chemistry. 2022 ; 120 105649-1-105649-12 + supplementary data: 1-13.[citado 2026 fev. 12 ] Available from: https://doi.org/10.1016/j.bioorg.2022.105649 - Natural compounds as non-nucleoside inhibitors of zika virus polymerase through integration of in silico and in vitro approaches
- Synthesis and evaluation of new ligands of the Zika virus NS3 helicase protein
- Total synthesis of Licochalcone G, enzymatic assays, and molecular docking studies against the Zika virus
- Licochalcone H and analogs as Zika virus NS2B-NS3 protease inhibitors: molecular docking and phenotypic assay
- Regioselective total synthesis and broad antiviral effects of Licochalcone C
- Flavonoids from Pterogyne nitens as Zika virus NS2B-NS3 protease inhibitors
- Discovery of new Zika protease and polymerase inhibitors through the open science collaboration Project OpenZika
- Discovery of new Zika virus candidates: natural products from Angelica keiskei with activity against NS2B-NS3 protease
- Discovery of flavonoids from Pterogyne nitens with potent activity against Zika virus protease and helicase
- Metiltransferase de flavivírus como obtê-las?
Informações sobre o DOI: 10.1016/j.bioorg.2022.105649 (Fonte: oaDOI API)
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