Flavonoids from Pterogyne nitens as Zika virus NS2B-NS3 protease inhibitors (2021)
- Authors:
- Lima, Caroline Sprengel
- Mottin, Melina
- Assis, Leticia Ribeiro de
- Mesquita, Nathalya Cristina de Moraes Roso
- Sousa, Bruna Katiele de Paula
- Coimbra, Lais Durco
- Santos, Karina Bispo dos
- Zorn, Kimberley M.
- Guido, Rafael Victorio Carvalho
- Ekins, Sean
- Marques, Rafael Elias
- Proença-Modena, José Luiz
- Oliva, Glaucius
- Andrade, Carolina Horta
- Regasini, Luis Octavio
- USP affiliated authors: GUIDO, RAFAEL VICTÓRIO CARVALHO - IFSC ; OLIVA, GLAUCIUS - IFSC ; MESQUITA, NATHALYA CRISTINA DE MORAES ROSO - IFSC
- Unidade: IFSC
- DOI: 10.1016/j.bioorg.2021.104719
- Subjects: ZIKA VÍRUS; PRODUTOS NATURAIS; FLAVIVIRIDAE; ENZIMAS; PROTEÍNAS; FARMACOLOGIA
- Keywords: Zika virus; Antiviral; Protease; Virtual screening; Drug discovery; NS3 protein; Flavonoid; Pterogyne nitens; Enzyme inhibitors; Emerging arboviruses
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Source:
- Título: Bioorganic Chemistry
- ISSN: 0045-2068
- Volume/Número/Paginação/Ano: v. 109, p. 104719-1-104719-9, Apr 2021
- Este periódico é de assinatura
- Este artigo é de acesso aberto
- URL de acesso aberto
- Cor do Acesso Aberto: green
-
ABNT
LIMA, Caroline Sprengel et al. Flavonoids from Pterogyne nitens as Zika virus NS2B-NS3 protease inhibitors. Bioorganic Chemistry, v. 109, p. 104719-1-104719-9, 2021Tradução . . Disponível em: https://doi.org/10.1016/j.bioorg.2021.104719. Acesso em: 28 dez. 2025. -
APA
Lima, C. S., Mottin, M., Assis, L. R. de, Mesquita, N. C. de M. R., Sousa, B. K. de P., Coimbra, L. D., et al. (2021). Flavonoids from Pterogyne nitens as Zika virus NS2B-NS3 protease inhibitors. Bioorganic Chemistry, 109, 104719-1-104719-9. doi:10.1016/j.bioorg.2021.104719 -
NLM
Lima CS, Mottin M, Assis LR de, Mesquita NC de MR, Sousa BK de P, Coimbra LD, Santos KB dos, Zorn KM, Guido RVC, Ekins S, Marques RE, Proença-Modena JL, Oliva G, Andrade CH, Regasini LO. Flavonoids from Pterogyne nitens as Zika virus NS2B-NS3 protease inhibitors [Internet]. Bioorganic Chemistry. 2021 ; 109 104719-1-104719-9.[citado 2025 dez. 28 ] Available from: https://doi.org/10.1016/j.bioorg.2021.104719 -
Vancouver
Lima CS, Mottin M, Assis LR de, Mesquita NC de MR, Sousa BK de P, Coimbra LD, Santos KB dos, Zorn KM, Guido RVC, Ekins S, Marques RE, Proença-Modena JL, Oliva G, Andrade CH, Regasini LO. Flavonoids from Pterogyne nitens as Zika virus NS2B-NS3 protease inhibitors [Internet]. Bioorganic Chemistry. 2021 ; 109 104719-1-104719-9.[citado 2025 dez. 28 ] Available from: https://doi.org/10.1016/j.bioorg.2021.104719 - Total synthesis of Licochalcone G, enzymatic assays, and molecular docking studies against the Zika virus
- Synthesis and evaluation of new ligands of the Zika virus NS3 helicase protein
- Regioselective total synthesis and broad antiviral effects of Licochalcone C
- Licochalcone H and analogs as Zika virus NS2B-NS3 protease inhibitors: molecular docking and phenotypic assay
- Natural compounds as non-nucleoside inhibitors of zika virus polymerase through integration of in silico and in vitro approaches
- A diarylamine derived from anthranilic acid inhibits ZIKV replication
- Discovery of flavonoids from Pterogyne nitens with potent activity against Zika virus protease and helicase
- Discovery of new Zika virus candidates: natural products from Angelica keiskei with activity against NS2B-NS3 protease
- Metiltransferase de flavivírus como obtê-las?
- Discovery of novel Zika virus NS3 protein inhibitors through the integration of docking, machine learning models and experimental evaluation
Informações sobre o DOI: 10.1016/j.bioorg.2021.104719 (Fonte: oaDOI API)
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