Transient NADPH oxidase 2-dependent H2O2 production drives early palmitate-induced lipotoxicity in pancreatic islets (2021)
- Authors:
- USP affiliated authors: ORTIS, FERNANDA - ICB ; CARPINELLI, ANGELO RAFAEL - ICB ; BÔAS, ELOÍSA APARECIDA VILAS - ICB
- Unidade: ICB
- DOI: 10.1016/j.freeradbiomed.2020.11.023
- Subjects: FISIOLOGIA; BIOLOGIA CELULAR; OBESIDADE; DIABETES MELLITUS; HÁBITOS ALIMENTARES; ÁCIDOS GRAXOS; ILHOTAS DE LANGERHANS; ESTRESSE OXIDATIVO; CAMUNDONGOS; INSULINA; HOMEOSTASE
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Publisher: Elsevier Inc.
- Publisher place: Philadelphia
- Date published: 2021
- Source:
- Título: Free Radical Biology & Medicine
- ISSN: 1873-4596
- Volume/Número/Paginação/Ano: v. 162, 13 p., 2021
- Este periódico é de assinatura
- Este artigo NÃO é de acesso aberto
- Cor do Acesso Aberto: closed
-
ABNT
VILAS-BOAS, Eloisa Aparecida et al. Transient NADPH oxidase 2-dependent H2O2 production drives early palmitate-induced lipotoxicity in pancreatic islets. Free Radical Biology & Medicine, v. 162, p. 13 , 2021Tradução . . Disponível em: https://doi.org/10.1016/j.freeradbiomed.2020.11.023. Acesso em: 26 dez. 2025. -
APA
Vilas-Boas, E. A., Nalbach, L., Ampofo, E., Lucena, C. F., Naudet, L., Morgan, B., et al. (2021). Transient NADPH oxidase 2-dependent H2O2 production drives early palmitate-induced lipotoxicity in pancreatic islets. Free Radical Biology & Medicine, 162, 13 . doi:10.1016/j.freeradbiomed.2020.11.023 -
NLM
Vilas-Boas EA, Nalbach L, Ampofo E, Lucena CF, Naudet L, Morgan B, Roma LP, Ortis F, Carpinelli AR. Transient NADPH oxidase 2-dependent H2O2 production drives early palmitate-induced lipotoxicity in pancreatic islets [Internet]. Free Radical Biology & Medicine. 2021 ; 162 13 .[citado 2025 dez. 26 ] Available from: https://doi.org/10.1016/j.freeradbiomed.2020.11.023 -
Vancouver
Vilas-Boas EA, Nalbach L, Ampofo E, Lucena CF, Naudet L, Morgan B, Roma LP, Ortis F, Carpinelli AR. Transient NADPH oxidase 2-dependent H2O2 production drives early palmitate-induced lipotoxicity in pancreatic islets [Internet]. Free Radical Biology & Medicine. 2021 ; 162 13 .[citado 2025 dez. 26 ] Available from: https://doi.org/10.1016/j.freeradbiomed.2020.11.023 - A role for NADPH oxidase in mediating lipotoxicity and inflammation in β-cells
- Lipotoxicity and β-cell failure in type 2 diabetes: oxidative stress linked to NADPH oxidase and ER stress
- Pro-inflammatory cytokines and beta cells death: role of cytosolic ROS
- Evidence for NADPH oxidase activation by GPR40 in pancreatic β-cells
- Chronic activation of GPR40 does not negatively impact upon BRIN-BD11 pancreatic β-cell physiology and function
- Expression, localization and regulation of NADPH oxidases in pancreatic beta cells
- Early cytokine-induced transient NOX2 activity is ER stress-dependent and impacts β-cell function and survival
- The non-canonical NF-κB pathway is induced by cytokines in pancreatic beta cells and contributes to cell death and proinflammatory responses in vitro
- Papel de BRG1 e Brm, reguladores globais de transcrição, na reversão fenotípica de células ST1 pela ação de glicocorticóides
- Augmented β-Cell function and mass in glucocorticoid-treated rodents are associated with increased islet Ir-β/AKT/mTOR and decreased AMPK/ACC and AS160 signaling
Informações sobre o DOI: 10.1016/j.freeradbiomed.2020.11.023 (Fonte: oaDOI API)
How to cite
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
