Optimization strategy of single-digit nanomolar cross-class inhibitors of mammalian and protozoa cysteine proteases (2020)
- Authors:
- USP affiliated authors: LEITÃO, ANDREI - IQSC ; MONTANARI, CARLOS ALBERTO - IQSC ; ROSINI, FABIANA - IQSC ; CIANNI, LORENZO - IQSC ; ROCHO, FERNANDA DOS REIS - IQSC ; BONATTO, VINÍCIUS - IQSC ; RIBEIRO, JEAN FRANCISCO ROSA - IQSC ; SHAMIM, ANWAR - IQSC
- Unidade: IQSC
- DOI: 10.1016/j.bioorg.2020.104039
- Subjects: FÁRMACOS; BIOMARCADORES; PROTEÍNAS
- Keywords: Cysteine protease inhibitors; Structure activity relationships; Molecular dynamics simulation; Matched molecular pair analysis; Isothermal titration calorimetry; Differential scanning calorimetry
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Publisher place: Maryland Heights
- Date published: 2020
- Source:
- Título do periódico: Bioorganic Chemistry
- ISSN: 0045-2068
- Volume/Número/Paginação/Ano: v. 101, art. 104039 June 2020
- Este periódico é de assinatura
- Este artigo NÃO é de acesso aberto
- Cor do Acesso Aberto: closed
-
ABNT
CIANNI, Lorenzo et al. Optimization strategy of single-digit nanomolar cross-class inhibitors of mammalian and protozoa cysteine proteases. Bioorganic Chemistry, v. 101, 2020Tradução . . Disponível em: https://doi.org/10.1016/j.bioorg.2020.104039. Acesso em: 23 abr. 2024. -
APA
Cianni, L., Rocho, F. dos R., Rosini, F., Bonatto, V., Ribeiro, J. F. R., Lameira, J., et al. (2020). Optimization strategy of single-digit nanomolar cross-class inhibitors of mammalian and protozoa cysteine proteases. Bioorganic Chemistry, 101. doi:10.1016/j.bioorg.2020.104039 -
NLM
Cianni L, Rocho F dos R, Rosini F, Bonatto V, Ribeiro JFR, Lameira J, Leitão A, Shamim A, Montanari CA. Optimization strategy of single-digit nanomolar cross-class inhibitors of mammalian and protozoa cysteine proteases [Internet]. Bioorganic Chemistry. 2020 ; 101[citado 2024 abr. 23 ] Available from: https://doi.org/10.1016/j.bioorg.2020.104039 -
Vancouver
Cianni L, Rocho F dos R, Rosini F, Bonatto V, Ribeiro JFR, Lameira J, Leitão A, Shamim A, Montanari CA. Optimization strategy of single-digit nanomolar cross-class inhibitors of mammalian and protozoa cysteine proteases [Internet]. Bioorganic Chemistry. 2020 ; 101[citado 2024 abr. 23 ] Available from: https://doi.org/10.1016/j.bioorg.2020.104039 - Predicting the Relative Binding Affinity for Reversible Covalent Inhibitors by Free Energy Perturbation Calculations
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- Mapping the S1 and S1’ subsites of cysteine proteases with new dipeptidyl nitrile inhibitors as trypanocidal agents
- Crystal structure of Leishmania mexicana cysteine protease B in complex with a high-affinity azadipeptide nitrile inhibitor
- Differential specificity of SARS-CoV-2 main protease variants on peptide versus protein-based substrates
- Evaluating QM/MM Free Energy Surfaces for Ranking Cysteine Protease Covalent Inhibitors
- Experimental study and computational modelling of cruzain cysteine protease inhibition by dipeptidyl nitriles
- The Effect of Dipeptidyl Nitrile Derivatives on Pancreatic Ductal Adenocarcinoma Cells In Vitro
Informações sobre o DOI: 10.1016/j.bioorg.2020.104039 (Fonte: oaDOI API)
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