Mapping the S1 and S1’ subsites of cysteine proteases with new dipeptidyl nitrile inhibitors as trypanocidal agents (2020)
- Authors:
- USP affiliated authors: LEITÃO, ANDREI - IQSC ; MONTANARI, CARLOS ALBERTO - IQSC ; ALBUQUERQUE, SÉRGIO DE - FCFRP ; CIANNI, LORENZO - IQSC ; ROSINI, FABIANA - IQSC ; ROCHO, FERNANDA DOS REIS - IQSC ; RIBEIRO, JEAN FRANCISCO ROSA - IQSC ; LOPES, CARLA DUQUE - FMRP
- Unidades: IQSC; FCFRP; FMRP
- DOI: 10.1371/journal.pntd.0007755
- Assunto: QUÍMICA MÉDICA
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Publisher place: San Francisco
- Date published: 2020
- Source:
- Título: PLoS Neglected Tropical Diseases
- ISSN: 1935-2735
- Volume/Número/Paginação/Ano: v. 14, n. 3, art. e0007755, p. 1-36, Mar., 2020
- Este periódico é de acesso aberto
- Este artigo é de acesso aberto
- URL de acesso aberto
- Cor do Acesso Aberto: gold
- Licença: cc-by
-
ABNT
CIANNI, Lorenzo et al. Mapping the S1 and S1’ subsites of cysteine proteases with new dipeptidyl nitrile inhibitors as trypanocidal agents. PLoS Neglected Tropical Diseases, v. 14, n. 3, p. 1-36, 2020Tradução . . Disponível em: https://doi.org/10.1371/journal.pntd.0007755. Acesso em: 28 dez. 2025. -
APA
Cianni, L., Lemke, C., Gilberg, E., Feldmann, C., Rosini, F., Rocho, F. dos R., et al. (2020). Mapping the S1 and S1’ subsites of cysteine proteases with new dipeptidyl nitrile inhibitors as trypanocidal agents. PLoS Neglected Tropical Diseases, 14( 3), 1-36. doi:10.1371/journal.pntd.0007755 -
NLM
Cianni L, Lemke C, Gilberg E, Feldmann C, Rosini F, Rocho F dos R, Ribeiro JFR, Tezuka DY, Lopes CD, Albuquerque S de, Bajorath J, Laufer S, Leitão A, Gütschow Michaell, Montanari CA. Mapping the S1 and S1’ subsites of cysteine proteases with new dipeptidyl nitrile inhibitors as trypanocidal agents [Internet]. PLoS Neglected Tropical Diseases. 2020 ; 14( 3): 1-36.[citado 2025 dez. 28 ] Available from: https://doi.org/10.1371/journal.pntd.0007755 -
Vancouver
Cianni L, Lemke C, Gilberg E, Feldmann C, Rosini F, Rocho F dos R, Ribeiro JFR, Tezuka DY, Lopes CD, Albuquerque S de, Bajorath J, Laufer S, Leitão A, Gütschow Michaell, Montanari CA. Mapping the S1 and S1’ subsites of cysteine proteases with new dipeptidyl nitrile inhibitors as trypanocidal agents [Internet]. PLoS Neglected Tropical Diseases. 2020 ; 14( 3): 1-36.[citado 2025 dez. 28 ] Available from: https://doi.org/10.1371/journal.pntd.0007755 - Crystal structure of Leishmania mexicana cysteine protease B in complex with a high-affinity azadipeptide nitrile inhibitor
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- Experimental study and computational modelling of cruzain cysteine protease inhibition by dipeptidyl nitriles
- The Effect of Dipeptidyl Nitrile Derivatives on Pancreatic Ductal Adenocarcinoma Cells In Vitro
- Predicting the ΔΔGbind of halogenated reversible covalent inhibitors of hCatL through computer simulation
- Predicting the affinity of halogenated reversible covalent inhibitors through relative binding free energy
- Can Cysteine Protease Cross-Class Inhibitors Achieve Selectivity?
- Molecular design aided by random forests and synthesis of potent trypanocidal agents as cruzain inhibitors for Chagas disease treatment
- Dipeptidyl nitrile derivatives have cytostatic effects against Leishmania spp. promastigotes
Informações sobre o DOI: 10.1371/journal.pntd.0007755 (Fonte: oaDOI API)
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