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Filtros : "Financiamento Bill and Melinda Gates Foundation Grand Challenges Explorations" "PLASMODIUM FALCIPARUM" Limpar

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  • Artigo de periodico

    Revisiting the Plasmodium falciparum druggable genome using predicted structures and data mining (2025)

    Godinez-Macias, Karla P.; Moura, Igor Mota Rodrigues de

    Fonte: npj Drug Discovery. Unidade: IFSC

    Assuntos: PLASMODIUM FALCIPARUM, PLANEJAMENTO DE FÁRMACOS, MALÁRIA

    Versão PublicadaAcesso à fonteDOIComo citar
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    • ABNT

      GODINEZ-MACIAS, Karla P. e MOURA, Igor Mota Rodrigues de. Revisiting the Plasmodium falciparum druggable genome using predicted structures and data mining. npj Drug Discovery, v. 2, p. 3-1-3-13 + supplementary information, 2025Tradução . . Disponível em: https://doi.org/10.1038/s44386-025-00006-5. Acesso em: 09 nov. 2025.

    • APA

      Godinez-Macias, K. P., & Moura, I. M. R. de. (2025). Revisiting the Plasmodium falciparum druggable genome using predicted structures and data mining. npj Drug Discovery, 2, 3-1-3-13 + supplementary information. doi:10.1038/s44386-025-00006-5

    • NLM

      Godinez-Macias KP, Moura IMR de. Revisiting the Plasmodium falciparum druggable genome using predicted structures and data mining [Internet]. npj Drug Discovery. 2025 ; 2 3-1-3-13 + supplementary information.[citado 2025 nov. 09 ] Available from: https://doi.org/10.1038/s44386-025-00006-5

    • Vancouver

      Godinez-Macias KP, Moura IMR de. Revisiting the Plasmodium falciparum druggable genome using predicted structures and data mining [Internet]. npj Drug Discovery. 2025 ; 2 3-1-3-13 + supplementary information.[citado 2025 nov. 09 ] Available from: https://doi.org/10.1038/s44386-025-00006-5

  • Artigo de periodico

    A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo (2024)

    Xie, Stanley C. ; Guido, Rafael Victorio Carvalho

    Fonte: PLOS Pathogens. Unidade: IFSC

    Assuntos: PLASMODIUM FALCIPARUM, ANTIMALÁRICOS, FÁRMACOS

    Versão PublicadaAcesso à fonteDOIComo citar
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    • ABNT

      XIE, Stanley C. e GUIDO, Rafael Victorio Carvalho. A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo. PLOS Pathogens, v. 20, n. 12, p. e1012429-1-e1012429-28 + supporting information, 2024Tradução . . Disponível em: https://doi.org/10.1371/journal.ppat.1012429. Acesso em: 09 nov. 2025.

    • APA

      Xie, S. C., & Guido, R. V. C. (2024). A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo. PLOS Pathogens, 20( 12), e1012429-1-e1012429-28 + supporting information. doi:10.1371/journal.ppat.1012429

    • NLM

      Xie SC, Guido RVC. A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo [Internet]. PLOS Pathogens. 2024 ; 20( 12): e1012429-1-e1012429-28 + supporting information.[citado 2025 nov. 09 ] Available from: https://doi.org/10.1371/journal.ppat.1012429

    • Vancouver

      Xie SC, Guido RVC. A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo [Internet]. PLOS Pathogens. 2024 ; 20( 12): e1012429-1-e1012429-28 + supporting information.[citado 2025 nov. 09 ] Available from: https://doi.org/10.1371/journal.ppat.1012429

  • Artigo de periodico

    Pyrimidine azepine targets the plasmodium bc1 complex and displays multistage antimalarial activit (2024)

    Calit, Juliana ; Prajapati , Surendra K.; Benavente, Ernest Diez ; Araújo, Jéssica Evangelista; Deng, Bingbing ; Miura, Kazutoyo ; Annunciato, Yasmin ; Moura, Igor Mota Rodrigues de ; Usui, Miho; Medeiros, Jansen Fernandes de ; Andrade, Carolina Horta ; Mendonça, Sabrina Silva; Simeonov, Anton; Eastman, Richard T. ; Long, Carole A. ; Araújo, Maisa da Silva ; Williamson, Kim C. ; Aguiar, Anna Caroline Campos ; Bargieri, Daniel Youssef

    Fonte: JACS Au. Unidades: ICB, IFSC

    Assuntos: MALÁRIA, PLANEJAMENTO DE FÁRMACOS, PLASMODIUM FALCIPARUM, ANTIMALÁRICOS

    Versão PublicadaAcesso à fonteDOIComo citar
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    • ABNT

      CALIT, Juliana et al. Pyrimidine azepine targets the plasmodium bc1 complex and displays multistage antimalarial activit. JACS Au, v. 4, n. 10, p. 3942-3952 + supporting information, 2024Tradução . . Disponível em: https://doi.org/10.1021/jacsau.4c00674. Acesso em: 09 nov. 2025.

    • APA

      Calit, J., Prajapati , S. K., Benavente, E. D., Araújo, J. E., Deng, B., Miura, K., et al. (2024). Pyrimidine azepine targets the plasmodium bc1 complex and displays multistage antimalarial activit. JACS Au, 4( 10), 3942-3952 + supporting information. doi:10.1021/jacsau.4c00674

    • NLM

      Calit J, Prajapati SK, Benavente ED, Araújo JE, Deng B, Miura K, Annunciato Y, Moura IMR de, Usui M, Medeiros JF de, Andrade CH, Mendonça SS, Simeonov A, Eastman RT, Long CA, Araújo M da S, Williamson KC, Aguiar ACC, Bargieri DY. Pyrimidine azepine targets the plasmodium bc1 complex and displays multistage antimalarial activit [Internet]. JACS Au. 2024 ; 4( 10): 3942-3952 + supporting information.[citado 2025 nov. 09 ] Available from: https://doi.org/10.1021/jacsau.4c00674

    • Vancouver

      Calit J, Prajapati SK, Benavente ED, Araújo JE, Deng B, Miura K, Annunciato Y, Moura IMR de, Usui M, Medeiros JF de, Andrade CH, Mendonça SS, Simeonov A, Eastman RT, Long CA, Araújo M da S, Williamson KC, Aguiar ACC, Bargieri DY. Pyrimidine azepine targets the plasmodium bc1 complex and displays multistage antimalarial activit [Internet]. JACS Au. 2024 ; 4( 10): 3942-3952 + supporting information.[citado 2025 nov. 09 ] Available from: https://doi.org/10.1021/jacsau.4c00674

  • Artigo de periodico

    Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183 (2022)

    Vries, Laura E. ; Aguiar, Anna Caroline Campos ; Guido, Rafael Victorio Carvalho

    Fonte: Nature Communications. Unidade: IFSC

    Assuntos: PLASMODIUM FALCIPARUM, PLANEJAMENTO DE FÁRMACOS, ANTIPARASITÁRIOS, MALÁRIA

    Versão PublicadaAcesso à fonteDOIComo citar
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    • ABNT

      VRIES, Laura E. e AGUIAR, Anna Caroline Campos e GUIDO, Rafael Victorio Carvalho. Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183. Nature Communications, v. 13, p. 2158-1-2158-16, 2022Tradução . . Disponível em: https://doi.org/10.1038/s41467-022-29688-5. Acesso em: 09 nov. 2025.

    • APA

      Vries, L. E., Aguiar, A. C. C., & Guido, R. V. C. (2022). Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183. Nature Communications, 13, 2158-1-2158-16. doi:10.1038/s41467-022-29688-5

    • NLM

      Vries LE, Aguiar ACC, Guido RVC. Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183 [Internet]. Nature Communications. 2022 ; 13 2158-1-2158-16.[citado 2025 nov. 09 ] Available from: https://doi.org/10.1038/s41467-022-29688-5

    • Vancouver

      Vries LE, Aguiar ACC, Guido RVC. Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183 [Internet]. Nature Communications. 2022 ; 13 2158-1-2158-16.[citado 2025 nov. 09 ] Available from: https://doi.org/10.1038/s41467-022-29688-5
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