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Artigo de periodico
Hit-to-lead optimization of a 2-aminobenzimidazole series as new candidates for chagas disease (2023)
Rezende Junior, Celso de Oliveira ; Martinez, Pablo David Grigol; Ferreira, Rafael Augusto Alves; Koovits, Paul John ; Soares, Bruna Miranda ; Ferreira, Leonardo Luiz Gomes ; Duarte, Simone Michelan ; Chelucci, Rafael Consolin; Andricopulo, Adriano Defini ; Matheeussen, An ; Van Pelt, Natascha; Caljon, Guy ; Maes, Louis ; Campbell, Simon; Kratz, Jadel Muller ; Mowbray, Charles E. ; Dias, Luiz Carlos
Source: European Journal of Medicinal Chemistry. Unidade: IFSC
Subjects: DOENÇA DE CHAGAS, PLANEJAMENTO DE FÁRMACOS, TRYPANOSOMA CRUZI
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ABNT
REZENDE JUNIOR, Celso de Oliveira et al. Hit-to-lead optimization of a 2-aminobenzimidazole series as new candidates for chagas disease. European Journal of Medicinal Chemistry, v. 246, n. Ja 2023, p. 114925-1-114925-10 + supplementary data, 2023Tradução . . Disponível em: https://doi.org/10.1016/j.ejmech.2022.114925. Acesso em: 05 nov. 2024.
APA
Rezende Junior, C. de O., Martinez, P. D. G., Ferreira, R. A. A., Koovits, P. J., Soares, B. M., Ferreira, L. L. G., et al. (2023). Hit-to-lead optimization of a 2-aminobenzimidazole series as new candidates for chagas disease. European Journal of Medicinal Chemistry, 246( Ja 2023), 114925-1-114925-10 + supplementary data. doi:10.1016/j.ejmech.2022.114925
NLM
Rezende Junior C de O, Martinez PDG, Ferreira RAA, Koovits PJ, Soares BM, Ferreira LLG, Duarte SM, Chelucci RC, Andricopulo AD, Matheeussen A, Van Pelt N, Caljon G, Maes L, Campbell S, Kratz JM, Mowbray CE, Dias LC. Hit-to-lead optimization of a 2-aminobenzimidazole series as new candidates for chagas disease [Internet]. European Journal of Medicinal Chemistry. 2023 ; 246( Ja 2023): 114925-1-114925-10 + supplementary data.[citado 2024 nov. 05 ] Available from: https://doi.org/10.1016/j.ejmech.2022.114925
Vancouver
Rezende Junior C de O, Martinez PDG, Ferreira RAA, Koovits PJ, Soares BM, Ferreira LLG, Duarte SM, Chelucci RC, Andricopulo AD, Matheeussen A, Van Pelt N, Caljon G, Maes L, Campbell S, Kratz JM, Mowbray CE, Dias LC. Hit-to-lead optimization of a 2-aminobenzimidazole series as new candidates for chagas disease [Internet]. European Journal of Medicinal Chemistry. 2023 ; 246( Ja 2023): 114925-1-114925-10 + supplementary data.[citado 2024 nov. 05 ] Available from: https://doi.org/10.1016/j.ejmech.2022.114925
Artigo de periodico
Discovery of highly potent and selective antiparasitic new oxadiazole and hydroxy-oxindole small molecule hybrids (2020)
Fernandes, Fábio S.; Santos, Hugo; Conti, Caroline; Rodrigues Junior, Manoel T.; Zeoly, Lucas A.; Ferreira, Leonardo Luiz Gomes ; Andricopulo, Renata Krogh; Andricopulo, Adriano Defini ; Coelho, Fernando
Source: European Journal of Medicinal Chemistry. Unidade: IFSC
Subjects: ANTIPARASITÁRIOS, TRYPANOSOMA CRUZI, LEISHMANIA INFANTUM, DOENÇA DE CHAGAS
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ABNT
FERNANDES, Fábio S. et al. Discovery of highly potent and selective antiparasitic new oxadiazole and hydroxy-oxindole small molecule hybrids. European Journal of Medicinal Chemistry, v. 201, p. 112418-1-112418-14, 2020Tradução . . Disponível em: https://doi.org/10.1016/j.ejmech.2020.112418. Acesso em: 05 nov. 2024.
APA
Fernandes, F. S., Santos, H., Conti, C., Rodrigues Junior, M. T., Zeoly, L. A., Ferreira, L. L. G., et al. (2020). Discovery of highly potent and selective antiparasitic new oxadiazole and hydroxy-oxindole small molecule hybrids. European Journal of Medicinal Chemistry, 201, 112418-1-112418-14. doi:10.1016/j.ejmech.2020.112418
NLM
Fernandes FS, Santos H, Conti C, Rodrigues Junior MT, Zeoly LA, Ferreira LLG, Andricopulo RK, Andricopulo AD, Coelho F. Discovery of highly potent and selective antiparasitic new oxadiazole and hydroxy-oxindole small molecule hybrids [Internet]. European Journal of Medicinal Chemistry. 2020 ; 201 112418-1-112418-14.[citado 2024 nov. 05 ] Available from: https://doi.org/10.1016/j.ejmech.2020.112418
Vancouver
Fernandes FS, Santos H, Conti C, Rodrigues Junior MT, Zeoly LA, Ferreira LLG, Andricopulo RK, Andricopulo AD, Coelho F. Discovery of highly potent and selective antiparasitic new oxadiazole and hydroxy-oxindole small molecule hybrids [Internet]. European Journal of Medicinal Chemistry. 2020 ; 201 112418-1-112418-14.[citado 2024 nov. 05 ] Available from: https://doi.org/10.1016/j.ejmech.2020.112418
Artigo de periodico
N-(10-naphthyl)-3,4,5-trimethoxybenzohydrazide as microtubule destabilizer: synthesis, cytotoxicity, inhibition of cell migration and in vivo activity against acute lymphoblastic leukemia (2015)
Salum, Lívia B.; Mascarello, Alessandra; Canevarolo, Rafael R.; Altei, Wanessa F.; Laranjeira, Angelo B. A.; Neuenfeldt, Patrícia D.; Stumpf, Taisa R.; Chiaradia-Delatorre, Louise D.; Vollmer, Laura L.; Daghestani, Hikmat N.; Melo, Carolina P. de Souza; Silveira, André B.; Leal, Paulo C.; Frederico, Marisa J. S.; Nascimento, Leandro F.; Santos, Adair R. S.; Andricopulo, Adriano Defini ; Day, Billy W.; Yunes, Rosendo A.; Vogt, Andreas; Yunes, José A.; Nunes, Ricardo J.
Source: European Journal of Medicinal Chemistry. Unidade: IFSC
Subjects: LEUCEMIA, NEOPLASIAS, CÉLULAS
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ABNT
SALUM, Lívia B. et al. N-(10-naphthyl)-3,4,5-trimethoxybenzohydrazide as microtubule destabilizer: synthesis, cytotoxicity, inhibition of cell migration and in vivo activity against acute lymphoblastic leukemia. European Journal of Medicinal Chemistry, v. 96, p. 504-518, 2015Tradução . . Disponível em: https://doi.org/10.1016/j.ejmech.2015.02.041. Acesso em: 05 nov. 2024.
APA
Salum, L. B., Mascarello, A., Canevarolo, R. R., Altei, W. F., Laranjeira, A. B. A., Neuenfeldt, P. D., et al. (2015). N-(10-naphthyl)-3,4,5-trimethoxybenzohydrazide as microtubule destabilizer: synthesis, cytotoxicity, inhibition of cell migration and in vivo activity against acute lymphoblastic leukemia. European Journal of Medicinal Chemistry, 96, 504-518. doi:10.1016/j.ejmech.2015.02.041
NLM
Salum LB, Mascarello A, Canevarolo RR, Altei WF, Laranjeira ABA, Neuenfeldt PD, Stumpf TR, Chiaradia-Delatorre LD, Vollmer LL, Daghestani HN, Melo CP de S, Silveira AB, Leal PC, Frederico MJS, Nascimento LF, Santos ARS, Andricopulo AD, Day BW, Yunes RA, Vogt A, Yunes JA, Nunes RJ. N-(10-naphthyl)-3,4,5-trimethoxybenzohydrazide as microtubule destabilizer: synthesis, cytotoxicity, inhibition of cell migration and in vivo activity against acute lymphoblastic leukemia [Internet]. European Journal of Medicinal Chemistry. 2015 ; 96 504-518.[citado 2024 nov. 05 ] Available from: https://doi.org/10.1016/j.ejmech.2015.02.041
Vancouver
Salum LB, Mascarello A, Canevarolo RR, Altei WF, Laranjeira ABA, Neuenfeldt PD, Stumpf TR, Chiaradia-Delatorre LD, Vollmer LL, Daghestani HN, Melo CP de S, Silveira AB, Leal PC, Frederico MJS, Nascimento LF, Santos ARS, Andricopulo AD, Day BW, Yunes RA, Vogt A, Yunes JA, Nunes RJ. N-(10-naphthyl)-3,4,5-trimethoxybenzohydrazide as microtubule destabilizer: synthesis, cytotoxicity, inhibition of cell migration and in vivo activity against acute lymphoblastic leukemia [Internet]. European Journal of Medicinal Chemistry. 2015 ; 96 504-518.[citado 2024 nov. 05 ] Available from: https://doi.org/10.1016/j.ejmech.2015.02.041
Artigo de periodico
Design, synthesis and biological evaluation of hybrid bioisoster derivatives of N-acylhydrazone and furoxan groups with potential and selective anti-Trypanosoma cruzi activity (2014)
Serafim, Ricardo Augusto Massarico; Gonçalves, José Eduardo; Souza, Felipe Pereira de; Loureiro, Ana Paula de Melo ; Storpirtis, Silvia ; Krogh, Renata; Andricopulo, Adriano Defini ; Dias, Luiz Carlos; Ferreira, Elizabeth Igne
Source: European Journal of Medicinal Chemistry. Unidades: FCF, IFSC
Subjects: TRYPANOSOMA CRUZI, INIBIDORES DE ENZIMAS, PLANEJAMENTO DE FÁRMACOS
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ABNT
SERAFIM, Ricardo Augusto Massarico et al. Design, synthesis and biological evaluation of hybrid bioisoster derivatives of N-acylhydrazone and furoxan groups with potential and selective anti-Trypanosoma cruzi activity. European Journal of Medicinal Chemistry, v. 82, p. 418-425, 2014Tradução . . Disponível em: https://doi.org/10.1016/j.ejmech.2014.05.077. Acesso em: 05 nov. 2024.
APA
Serafim, R. A. M., Gonçalves, J. E., Souza, F. P. de, Loureiro, A. P. de M., Storpirtis, S., Krogh, R., et al. (2014). Design, synthesis and biological evaluation of hybrid bioisoster derivatives of N-acylhydrazone and furoxan groups with potential and selective anti-Trypanosoma cruzi activity. European Journal of Medicinal Chemistry, 82, 418-425. doi:10.1016/j.ejmech.2014.05.077
NLM
Serafim RAM, Gonçalves JE, Souza FP de, Loureiro AP de M, Storpirtis S, Krogh R, Andricopulo AD, Dias LC, Ferreira EI. Design, synthesis and biological evaluation of hybrid bioisoster derivatives of N-acylhydrazone and furoxan groups with potential and selective anti-Trypanosoma cruzi activity [Internet]. European Journal of Medicinal Chemistry. 2014 ; 82 418-425.[citado 2024 nov. 05 ] Available from: https://doi.org/10.1016/j.ejmech.2014.05.077
Vancouver
Serafim RAM, Gonçalves JE, Souza FP de, Loureiro AP de M, Storpirtis S, Krogh R, Andricopulo AD, Dias LC, Ferreira EI. Design, synthesis and biological evaluation of hybrid bioisoster derivatives of N-acylhydrazone and furoxan groups with potential and selective anti-Trypanosoma cruzi activity [Internet]. European Journal of Medicinal Chemistry. 2014 ; 82 418-425.[citado 2024 nov. 05 ] Available from: https://doi.org/10.1016/j.ejmech.2014.05.077
Artigo de periodico
Cytotoxic 3,4,5-trimethoxychalcones as mitotic arresters and cell migration inhibitors (2013)
Salum, Lívia B.; Altei, Wanessa F.; Chiaradia, Louise D.; Cordeiro, Marlon N. S.; Canevarolo, Rafael R.; Melo, Carolina P. S.; Winter, Evelyn; Mattei, Bruno; Daghestani, Hikmat N.; Silva, Maria Cláudia Santos; Creczynski-Pasa, Tânia B.; Yunes, Rosendo A.; Yunes, José A.; Andricopulo, Adriano Defini ; Day, Billy W.; Nunes, Ricardo J.; Vogt, Andreas
Source: European Journal of Medicinal Chemistry. Unidade: IFSC
Subjects: LIGANTES, NEOPLASIAS (TRATAMENTO), FÁRMACOS (DESENVOLVIMENTO)
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ABNT
SALUM, Lívia B. et al. Cytotoxic 3,4,5-trimethoxychalcones as mitotic arresters and cell migration inhibitors. European Journal of Medicinal Chemistry, v. 63, p. 501-510, 2013Tradução . . Disponível em: https://doi.org/10.1016/j.ejmech.2013.02.037. Acesso em: 05 nov. 2024.
APA
Salum, L. B., Altei, W. F., Chiaradia, L. D., Cordeiro, M. N. S., Canevarolo, R. R., Melo, C. P. S., et al. (2013). Cytotoxic 3,4,5-trimethoxychalcones as mitotic arresters and cell migration inhibitors. European Journal of Medicinal Chemistry, 63, 501-510. doi:10.1016/j.ejmech.2013.02.037
NLM
Salum LB, Altei WF, Chiaradia LD, Cordeiro MNS, Canevarolo RR, Melo CPS, Winter E, Mattei B, Daghestani HN, Silva MCS, Creczynski-Pasa TB, Yunes RA, Yunes JA, Andricopulo AD, Day BW, Nunes RJ, Vogt A. Cytotoxic 3,4,5-trimethoxychalcones as mitotic arresters and cell migration inhibitors [Internet]. European Journal of Medicinal Chemistry. 2013 ; 63 501-510.[citado 2024 nov. 05 ] Available from: https://doi.org/10.1016/j.ejmech.2013.02.037
Vancouver
Salum LB, Altei WF, Chiaradia LD, Cordeiro MNS, Canevarolo RR, Melo CPS, Winter E, Mattei B, Daghestani HN, Silva MCS, Creczynski-Pasa TB, Yunes RA, Yunes JA, Andricopulo AD, Day BW, Nunes RJ, Vogt A. Cytotoxic 3,4,5-trimethoxychalcones as mitotic arresters and cell migration inhibitors [Internet]. European Journal of Medicinal Chemistry. 2013 ; 63 501-510.[citado 2024 nov. 05 ] Available from: https://doi.org/10.1016/j.ejmech.2013.02.037
Artigo de periodico
Synthetic chalcones and sulfonamides as new classes of Yersinia enterocolitica YopH tyrosine phosphatase inhibitors (2013)
Martins, Priscila Graziela Alves; Menegatti, Angela Camila Orbem; Delatorre, Louise Domeneghini Chiaradia; Oliveira, Kely Navakoski de; Guido, Rafael Victorio Carvalho ; Andricopulo, Adriano Defini ; Vernal, Javier; Yunes, Rosendo Augusto; Nunes, Ricardo José; Terenzi, Hernán
Source: European Journal of Medicinal Chemistry. Unidade: IFSC
Subjects: PROTEÍNAS, INIBIDORES DE ENZIMAS, BACTÉRIAS (ESTUDO)
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ABNT
MARTINS, Priscila Graziela Alves et al. Synthetic chalcones and sulfonamides as new classes of Yersinia enterocolitica YopH tyrosine phosphatase inhibitors. European Journal of Medicinal Chemistry, v. 64, p. 35-41, 2013Tradução . . Disponível em: https://doi.org/10.1016/j.ejmech.2013.04.018. Acesso em: 05 nov. 2024.
APA
Martins, P. G. A., Menegatti, A. C. O., Delatorre, L. D. C., Oliveira, K. N. de, Guido, R. V. C., Andricopulo, A. D., et al. (2013). Synthetic chalcones and sulfonamides as new classes of Yersinia enterocolitica YopH tyrosine phosphatase inhibitors. European Journal of Medicinal Chemistry, 64, 35-41. doi:10.1016/j.ejmech.2013.04.018
NLM
Martins PGA, Menegatti ACO, Delatorre LDC, Oliveira KN de, Guido RVC, Andricopulo AD, Vernal J, Yunes RA, Nunes RJ, Terenzi H. Synthetic chalcones and sulfonamides as new classes of Yersinia enterocolitica YopH tyrosine phosphatase inhibitors [Internet]. European Journal of Medicinal Chemistry. 2013 ; 64 35-41.[citado 2024 nov. 05 ] Available from: https://doi.org/10.1016/j.ejmech.2013.04.018
Vancouver
Martins PGA, Menegatti ACO, Delatorre LDC, Oliveira KN de, Guido RVC, Andricopulo AD, Vernal J, Yunes RA, Nunes RJ, Terenzi H. Synthetic chalcones and sulfonamides as new classes of Yersinia enterocolitica YopH tyrosine phosphatase inhibitors [Internet]. European Journal of Medicinal Chemistry. 2013 ; 64 35-41.[citado 2024 nov. 05 ] Available from: https://doi.org/10.1016/j.ejmech.2013.04.018
Artigo de periodico
Design and synthesis of new (E)-cinnamic N-acylhydrazones as potent antitrypanosomal agents (2012)
Carvalho, Samir A.; Feitosa, Larisse O.; Soares, Márcio; Costa, Thadeu E. M. M.; Henriques, Maria G.; Salomão, Kelly; Castro, Solange L.; Kaiser, Marcel; Brun, Reto; Wardell, James L.; Wardell, Solange M. S. V.; Trossini, Gustavo Henrique Goulart ; Andricopulo, Adriano Defini ; Silva, Edson F.; Fraga, Carlos A. M.
Source: European Journal of Medicinal Chemistry. Unidades: FCF, IFSC
Subjects: DOENÇA DE CHAGAS, TRIPANOSSOMICIDAS, INIBIDORES DE ENZIMAS
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ABNT
CARVALHO, Samir A. et al. Design and synthesis of new (E)-cinnamic N-acylhydrazones as potent antitrypanosomal agents. European Journal of Medicinal Chemistry, v. 54, p. 512-521, 2012Tradução . . Disponível em: https://doi.org/10.1016/j.ejmech.2012.05.041. Acesso em: 05 nov. 2024.
APA
Carvalho, S. A., Feitosa, L. O., Soares, M., Costa, T. E. M. M., Henriques, M. G., Salomão, K., et al. (2012). Design and synthesis of new (E)-cinnamic N-acylhydrazones as potent antitrypanosomal agents. European Journal of Medicinal Chemistry, 54, 512-521. doi:10.1016/j.ejmech.2012.05.041
NLM
Carvalho SA, Feitosa LO, Soares M, Costa TEMM, Henriques MG, Salomão K, Castro SL, Kaiser M, Brun R, Wardell JL, Wardell SMSV, Trossini GHG, Andricopulo AD, Silva EF, Fraga CAM. Design and synthesis of new (E)-cinnamic N-acylhydrazones as potent antitrypanosomal agents [Internet]. European Journal of Medicinal Chemistry. 2012 ; 54 512-521.[citado 2024 nov. 05 ] Available from: https://doi.org/10.1016/j.ejmech.2012.05.041
Vancouver
Carvalho SA, Feitosa LO, Soares M, Costa TEMM, Henriques MG, Salomão K, Castro SL, Kaiser M, Brun R, Wardell JL, Wardell SMSV, Trossini GHG, Andricopulo AD, Silva EF, Fraga CAM. Design and synthesis of new (E)-cinnamic N-acylhydrazones as potent antitrypanosomal agents [Internet]. European Journal of Medicinal Chemistry. 2012 ; 54 512-521.[citado 2024 nov. 05 ] Available from: https://doi.org/10.1016/j.ejmech.2012.05.041
Artigo de periodico
Pharmacophore-based 3D QSAR studies on a series of high affinity 5-H'T IND.1A' receptor ligands (2010)
Weber, Karen C.; Salum, Lívia B.; Honório, Káthia Maria; Andricopulo, Adriano Defini ; Silva, Alberico Borges Ferreira da
Source: European Journal of Medicinal Chemistry. Unidades: EACH, IFSC, IQSC
Subjects: PLANEJAMENTO DE FÁRMACOS, RECEPTORES DE SEROTONINA, RELAÇÕES QUANTITATIVAS ENTRE ESTRUTURA QUÍMICA E ATIVIDADE BIOLÓGICA, BIOLOGIA MOLECULAR, QUÍMICA MÉDICA, LIGANTES
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ABNT
WEBER, Karen C. et al. Pharmacophore-based 3D QSAR studies on a series of high affinity 5-H'T IND.1A' receptor ligands. European Journal of Medicinal Chemistry, v. 45, n. 4, p. 1508-1514, 2010Tradução . . Disponível em: https://doi.org/10.1016/j.ejmech.2009.12.059. Acesso em: 05 nov. 2024.
APA
Weber, K. C., Salum, L. B., Honório, K. M., Andricopulo, A. D., & Silva, A. B. F. da. (2010). Pharmacophore-based 3D QSAR studies on a series of high affinity 5-H'T IND.1A' receptor ligands. European Journal of Medicinal Chemistry, 45( 4), 1508-1514. doi:10.1016/j.ejmech.2009.12.059
NLM
Weber KC, Salum LB, Honório KM, Andricopulo AD, Silva ABF da. Pharmacophore-based 3D QSAR studies on a series of high affinity 5-H'T IND.1A' receptor ligands [Internet]. European Journal of Medicinal Chemistry. 2010 ; 45( 4): 1508-1514.[citado 2024 nov. 05 ] Available from: https://doi.org/10.1016/j.ejmech.2009.12.059
Vancouver
Weber KC, Salum LB, Honório KM, Andricopulo AD, Silva ABF da. Pharmacophore-based 3D QSAR studies on a series of high affinity 5-H'T IND.1A' receptor ligands [Internet]. European Journal of Medicinal Chemistry. 2010 ; 45( 4): 1508-1514.[citado 2024 nov. 05 ] Available from: https://doi.org/10.1016/j.ejmech.2009.12.059
Artigo de periodico
In silico screening of HIV-1 non-nucleoside reverse transcriptase and protease inhibitors (2008)
Leitão, Andrei ; Andricopulo, Adriano Defini ; Montanari, Carlos Alberto
Source: European Journal of Medicinal Chemistry. Unidades: IFSC, IQSC
Subjects: PLANEJAMENTO DE FÁRMACOS, TRANSCRIÇÃO GÊNICA, HIV, INIBIDORES DE ENZIMAS, PROTEÍNAS, BIOLOGIA MOLECULAR (ATIVIDADE), PLANEJAMENTO DE FÁRMACOS (ESTRUTURA)
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ABNT
LEITÃO, Andrei e ANDRICOPULO, Adriano Defini e MONTANARI, Carlos Alberto. In silico screening of HIV-1 non-nucleoside reverse transcriptase and protease inhibitors. European Journal of Medicinal Chemistry, v. 43, n. 7, p. 1412-1422, 2008Tradução . . Disponível em: https://doi.org/10.1016/j.ejmech.2007.08.017. Acesso em: 05 nov. 2024.
APA
Leitão, A., Andricopulo, A. D., & Montanari, C. A. (2008). In silico screening of HIV-1 non-nucleoside reverse transcriptase and protease inhibitors. European Journal of Medicinal Chemistry, 43( 7), 1412-1422. doi:10.1016/j.ejmech.2007.08.017
NLM
Leitão A, Andricopulo AD, Montanari CA. In silico screening of HIV-1 non-nucleoside reverse transcriptase and protease inhibitors [Internet]. European Journal of Medicinal Chemistry. 2008 ; 43( 7): 1412-1422.[citado 2024 nov. 05 ] Available from: https://doi.org/10.1016/j.ejmech.2007.08.017
Vancouver
Leitão A, Andricopulo AD, Montanari CA. In silico screening of HIV-1 non-nucleoside reverse transcriptase and protease inhibitors [Internet]. European Journal of Medicinal Chemistry. 2008 ; 43( 7): 1412-1422.[citado 2024 nov. 05 ] Available from: https://doi.org/10.1016/j.ejmech.2007.08.017

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