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Artigo de periodico
Discovery of new piperaquine hybrid analogs linked by triazolopyrimidine and pyrazolopyrimidine scaffolds with antiplasmodial and transmission blocking activities (2024)
Feitosa, Lívia Melo; França, Rodolfo Rodrigo Florido; Ferreira, Maria de Lourdes Garcia; Aguiar, Anna Caroline Campos ; Souza, Guilherme Eduardo de ; Maluf, Sarah El Chamy; Souza, Juliana Oliveira de; Zapata, Luana Carlos Campisano ; Duarte, Denise Maria Figueiredo Araújo ; Morais, Inês ; Nogueira, Fátima ; Nonato, Maria Cristina ; Pinheiro, Luiz Carlos da Silva; Guido, Rafael Victorio Carvalho ; Boechat, Núbia
Source: European Journal of Medicinal Chemistry. Unidades: FCFRP, IFSC
Subjects: DOENÇA DE CHAGAS, PLANEJAMENTO DE FÁRMACOS, TRYPANOSOMA CRUZI
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ABNT
FEITOSA, Lívia Melo et al. Discovery of new piperaquine hybrid analogs linked by triazolopyrimidine and pyrazolopyrimidine scaffolds with antiplasmodial and transmission blocking activities. European Journal of Medicinal Chemistry, v. 267, p. 116163-1-116163-12, 2024Tradução . . Disponível em: https://doi.org/10.1016/j.ejmech.2024.116163. Acesso em: 06 nov. 2024.
APA
Feitosa, L. M., França, R. R. F., Ferreira, M. de L. G., Aguiar, A. C. C., Souza, G. E. de, Maluf, S. E. C., et al. (2024). Discovery of new piperaquine hybrid analogs linked by triazolopyrimidine and pyrazolopyrimidine scaffolds with antiplasmodial and transmission blocking activities. European Journal of Medicinal Chemistry, 267, 116163-1-116163-12. doi:10.1016/j.ejmech.2024.116163
NLM
Feitosa LM, França RRF, Ferreira M de LG, Aguiar ACC, Souza GE de, Maluf SEC, Souza JO de, Zapata LCC, Duarte DMFA, Morais I, Nogueira F, Nonato MC, Pinheiro LC da S, Guido RVC, Boechat N. Discovery of new piperaquine hybrid analogs linked by triazolopyrimidine and pyrazolopyrimidine scaffolds with antiplasmodial and transmission blocking activities [Internet]. European Journal of Medicinal Chemistry. 2024 ; 267 116163-1-116163-12.[citado 2024 nov. 06 ] Available from: https://doi.org/10.1016/j.ejmech.2024.116163
Vancouver
Feitosa LM, França RRF, Ferreira M de LG, Aguiar ACC, Souza GE de, Maluf SEC, Souza JO de, Zapata LCC, Duarte DMFA, Morais I, Nogueira F, Nonato MC, Pinheiro LC da S, Guido RVC, Boechat N. Discovery of new piperaquine hybrid analogs linked by triazolopyrimidine and pyrazolopyrimidine scaffolds with antiplasmodial and transmission blocking activities [Internet]. European Journal of Medicinal Chemistry. 2024 ; 267 116163-1-116163-12.[citado 2024 nov. 06 ] Available from: https://doi.org/10.1016/j.ejmech.2024.116163
Artigo de periodico
Hit-to-lead optimization of a 2-aminobenzimidazole series as new candidates for chagas disease (2023)
Rezende Junior, Celso de Oliveira ; Martinez, Pablo David Grigol; Ferreira, Rafael Augusto Alves; Koovits, Paul John ; Soares, Bruna Miranda ; Ferreira, Leonardo Luiz Gomes ; Duarte, Simone Michelan ; Chelucci, Rafael Consolin; Andricopulo, Adriano Defini ; Matheeussen, An ; Van Pelt, Natascha; Caljon, Guy ; Maes, Louis ; Campbell, Simon; Kratz, Jadel Muller ; Mowbray, Charles E. ; Dias, Luiz Carlos
Source: European Journal of Medicinal Chemistry. Unidade: IFSC
Subjects: DOENÇA DE CHAGAS, PLANEJAMENTO DE FÁRMACOS, TRYPANOSOMA CRUZI
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ABNT
REZENDE JUNIOR, Celso de Oliveira et al. Hit-to-lead optimization of a 2-aminobenzimidazole series as new candidates for chagas disease. European Journal of Medicinal Chemistry, v. 246, n. Ja 2023, p. 114925-1-114925-10 + supplementary data, 2023Tradução . . Disponível em: https://doi.org/10.1016/j.ejmech.2022.114925. Acesso em: 06 nov. 2024.
APA
Rezende Junior, C. de O., Martinez, P. D. G., Ferreira, R. A. A., Koovits, P. J., Soares, B. M., Ferreira, L. L. G., et al. (2023). Hit-to-lead optimization of a 2-aminobenzimidazole series as new candidates for chagas disease. European Journal of Medicinal Chemistry, 246( Ja 2023), 114925-1-114925-10 + supplementary data. doi:10.1016/j.ejmech.2022.114925
NLM
Rezende Junior C de O, Martinez PDG, Ferreira RAA, Koovits PJ, Soares BM, Ferreira LLG, Duarte SM, Chelucci RC, Andricopulo AD, Matheeussen A, Van Pelt N, Caljon G, Maes L, Campbell S, Kratz JM, Mowbray CE, Dias LC. Hit-to-lead optimization of a 2-aminobenzimidazole series as new candidates for chagas disease [Internet]. European Journal of Medicinal Chemistry. 2023 ; 246( Ja 2023): 114925-1-114925-10 + supplementary data.[citado 2024 nov. 06 ] Available from: https://doi.org/10.1016/j.ejmech.2022.114925
Vancouver
Rezende Junior C de O, Martinez PDG, Ferreira RAA, Koovits PJ, Soares BM, Ferreira LLG, Duarte SM, Chelucci RC, Andricopulo AD, Matheeussen A, Van Pelt N, Caljon G, Maes L, Campbell S, Kratz JM, Mowbray CE, Dias LC. Hit-to-lead optimization of a 2-aminobenzimidazole series as new candidates for chagas disease [Internet]. European Journal of Medicinal Chemistry. 2023 ; 246( Ja 2023): 114925-1-114925-10 + supplementary data.[citado 2024 nov. 06 ] Available from: https://doi.org/10.1016/j.ejmech.2022.114925
Artigo de periodico
New ruthenium complexes containing salicylic acid and derivatives induce triple-negative tumor cell death via the intrinsic apoptotic pathway (2022)
Graminha, Angelica E.; Popolin, Cecília; Araujo Neto, João Honorato ; Correa, Rodrigo S. ; Oliveira, Katia Mara de ; Godoy, Luani R.; Vegas, Legna Colina; Ellena, Javier ; Batista, Alzir Azevedo ; Cominetti, Marcia Regina
Source: European Journal of Medicinal Chemistry. Unidade: IFSC
Subjects: RUTÊNIO, CITOTOXINAS, APOPTOSE
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ABNT
GRAMINHA, Angelica E. et al. New ruthenium complexes containing salicylic acid and derivatives induce triple-negative tumor cell death via the intrinsic apoptotic pathway. European Journal of Medicinal Chemistry, v. 243, p. 114772-1-114772-14 + supplementary data, 2022Tradução . . Disponível em: https://doi.org/10.1016/j.ejmech.2022.114772. Acesso em: 06 nov. 2024.
APA
Graminha, A. E., Popolin, C., Araujo Neto, J. H., Correa, R. S., Oliveira, K. M. de, Godoy, L. R., et al. (2022). New ruthenium complexes containing salicylic acid and derivatives induce triple-negative tumor cell death via the intrinsic apoptotic pathway. European Journal of Medicinal Chemistry, 243, 114772-1-114772-14 + supplementary data. doi:10.1016/j.ejmech.2022.114772
NLM
Graminha AE, Popolin C, Araujo Neto JH, Correa RS, Oliveira KM de, Godoy LR, Vegas LC, Ellena J, Batista AA, Cominetti MR. New ruthenium complexes containing salicylic acid and derivatives induce triple-negative tumor cell death via the intrinsic apoptotic pathway [Internet]. European Journal of Medicinal Chemistry. 2022 ; 243 114772-1-114772-14 + supplementary data.[citado 2024 nov. 06 ] Available from: https://doi.org/10.1016/j.ejmech.2022.114772
Vancouver
Graminha AE, Popolin C, Araujo Neto JH, Correa RS, Oliveira KM de, Godoy LR, Vegas LC, Ellena J, Batista AA, Cominetti MR. New ruthenium complexes containing salicylic acid and derivatives induce triple-negative tumor cell death via the intrinsic apoptotic pathway [Internet]. European Journal of Medicinal Chemistry. 2022 ; 243 114772-1-114772-14 + supplementary data.[citado 2024 nov. 06 ] Available from: https://doi.org/10.1016/j.ejmech.2022.114772
Artigo de periodico
Parasitological profiling shows 4(1H)-quinolone derivatives as new lead candidates for malaria (2021)
Souza, Juliana Oliveira de; Almeida, Suzete M.; Souza, Guilherme Eduardo de ; Zanini, Camila Lima; Silva, Everton Machado da; Paim, Juliana Calit ; Bargieri, Daniel Youssef ; Amporndanai, Kangsa; Antonyuk, Svetlana V. ; Hasnain, S. Samar ; Cruz, Fabio C.; Pereira, Dhelio Batista ; Oliva, Glaucius ; Corrêa, Arlene G. ; Aguiar, Anna Caroline Campos ; Guido, Rafael Victorio Carvalho
Source: European Journal of Medicinal Chemistry Reports. Unidades: ICB, IFSC
Subjects: ANTIMALÁRICOS, ANTIPARASITÁRIOS, MALÁRIA, PLASMODIUM FALCIPARUM
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ABNT
SOUZA, Juliana Oliveira de et al. Parasitological profiling shows 4(1H)-quinolone derivatives as new lead candidates for malaria. European Journal of Medicinal Chemistry Reports, v. 3, p. 100012-1-100012-16 + supplementary data, 2021Tradução . . Disponível em: https://doi.org/10.1016/j.ejmcr.2021.100012. Acesso em: 06 nov. 2024.
APA
Souza, J. O. de, Almeida, S. M., Souza, G. E. de, Zanini, C. L., Silva, E. M. da, Paim, J. C., et al. (2021). Parasitological profiling shows 4(1H)-quinolone derivatives as new lead candidates for malaria. European Journal of Medicinal Chemistry Reports, 3, 100012-1-100012-16 + supplementary data. doi:10.1016/j.ejmcr.2021.100012
NLM
Souza JO de, Almeida SM, Souza GE de, Zanini CL, Silva EM da, Paim JC, Bargieri DY, Amporndanai K, Antonyuk SV, Hasnain SS, Cruz FC, Pereira DB, Oliva G, Corrêa AG, Aguiar ACC, Guido RVC. Parasitological profiling shows 4(1H)-quinolone derivatives as new lead candidates for malaria [Internet]. European Journal of Medicinal Chemistry Reports. 2021 ; 3 100012-1-100012-16 + supplementary data.[citado 2024 nov. 06 ] Available from: https://doi.org/10.1016/j.ejmcr.2021.100012
Vancouver
Souza JO de, Almeida SM, Souza GE de, Zanini CL, Silva EM da, Paim JC, Bargieri DY, Amporndanai K, Antonyuk SV, Hasnain SS, Cruz FC, Pereira DB, Oliva G, Corrêa AG, Aguiar ACC, Guido RVC. Parasitological profiling shows 4(1H)-quinolone derivatives as new lead candidates for malaria [Internet]. European Journal of Medicinal Chemistry Reports. 2021 ; 3 100012-1-100012-16 + supplementary data.[citado 2024 nov. 06 ] Available from: https://doi.org/10.1016/j.ejmcr.2021.100012
Artigo de periodico
Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors (2021)
Silveira, Flávia F.; Souza, Juliana Oliveira de; Hoelz, Lucas V. B.; Campos, Vinícius R.; Jabor, Valquíria Aparecida Polisel; Aguiar, Anna Caroline Campos; Nonato, Maria Cristina ; Albuquerque, Magaly G. ; Guido, Rafael Victorio Carvalho ; Boechat, Nubia; Pinheiro, Luiz C. S.
Source: European Journal of Medicinal Chemistry. Unidades: IFSC, FCFRP
Subjects: ANTIMALÁRICOS, ANTIPARASITÁRIOS, MALÁRIA
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ABNT
SILVEIRA, Flávia F. et al. Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors. European Journal of Medicinal Chemistry, v. 209, n. Ja 2021, p. 112941-1-112941-16, 2021Tradução . . Disponível em: https://doi.org/10.1016/j.ejmech.2020.112941. Acesso em: 06 nov. 2024.
APA
Silveira, F. F., Souza, J. O. de, Hoelz, L. V. B., Campos, V. R., Jabor, V. A. P., Aguiar, A. C. C., et al. (2021). Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors. European Journal of Medicinal Chemistry, 209( Ja 2021), 112941-1-112941-16. doi:10.1016/j.ejmech.2020.112941
NLM
Silveira FF, Souza JO de, Hoelz LVB, Campos VR, Jabor VAP, Aguiar ACC, Nonato MC, Albuquerque MG, Guido RVC, Boechat N, Pinheiro LCS. Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors [Internet]. European Journal of Medicinal Chemistry. 2021 ; 209( Ja 2021): 112941-1-112941-16.[citado 2024 nov. 06 ] Available from: https://doi.org/10.1016/j.ejmech.2020.112941
Vancouver
Silveira FF, Souza JO de, Hoelz LVB, Campos VR, Jabor VAP, Aguiar ACC, Nonato MC, Albuquerque MG, Guido RVC, Boechat N, Pinheiro LCS. Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors [Internet]. European Journal of Medicinal Chemistry. 2021 ; 209( Ja 2021): 112941-1-112941-16.[citado 2024 nov. 06 ] Available from: https://doi.org/10.1016/j.ejmech.2020.112941
Artigo de periodico
Discovery of highly potent and selective antiparasitic new oxadiazole and hydroxy-oxindole small molecule hybrids (2020)
Fernandes, Fábio S.; Santos, Hugo; Conti, Caroline; Rodrigues Junior, Manoel T.; Zeoly, Lucas A.; Ferreira, Leonardo Luiz Gomes ; Andricopulo, Renata Krogh; Andricopulo, Adriano Defini ; Coelho, Fernando
Source: European Journal of Medicinal Chemistry. Unidade: IFSC
Subjects: ANTIPARASITÁRIOS, TRYPANOSOMA CRUZI, LEISHMANIA INFANTUM, DOENÇA DE CHAGAS
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ABNT
FERNANDES, Fábio S. et al. Discovery of highly potent and selective antiparasitic new oxadiazole and hydroxy-oxindole small molecule hybrids. European Journal of Medicinal Chemistry, v. 201, p. 112418-1-112418-14, 2020Tradução . . Disponível em: https://doi.org/10.1016/j.ejmech.2020.112418. Acesso em: 06 nov. 2024.
APA
Fernandes, F. S., Santos, H., Conti, C., Rodrigues Junior, M. T., Zeoly, L. A., Ferreira, L. L. G., et al. (2020). Discovery of highly potent and selective antiparasitic new oxadiazole and hydroxy-oxindole small molecule hybrids. European Journal of Medicinal Chemistry, 201, 112418-1-112418-14. doi:10.1016/j.ejmech.2020.112418
NLM
Fernandes FS, Santos H, Conti C, Rodrigues Junior MT, Zeoly LA, Ferreira LLG, Andricopulo RK, Andricopulo AD, Coelho F. Discovery of highly potent and selective antiparasitic new oxadiazole and hydroxy-oxindole small molecule hybrids [Internet]. European Journal of Medicinal Chemistry. 2020 ; 201 112418-1-112418-14.[citado 2024 nov. 06 ] Available from: https://doi.org/10.1016/j.ejmech.2020.112418
Vancouver
Fernandes FS, Santos H, Conti C, Rodrigues Junior MT, Zeoly LA, Ferreira LLG, Andricopulo RK, Andricopulo AD, Coelho F. Discovery of highly potent and selective antiparasitic new oxadiazole and hydroxy-oxindole small molecule hybrids [Internet]. European Journal of Medicinal Chemistry. 2020 ; 201 112418-1-112418-14.[citado 2024 nov. 06 ] Available from: https://doi.org/10.1016/j.ejmech.2020.112418
Artigo de periodico
Analysis of two Schistosoma mansoni uridine phosphorylases isoforms suggests the emergence of a protein with a non-canonical function (2016)
Silva Neto, Antônio Marinho da; Souza, Juliana Roberta Torini de; Romanello, Larissa; Cassago, Alexandre; Serrão, Vitor Hugo Balasco; De Marco, Ricardo; Brandão-Neto, José; Garratt, Richard Charles ; Pereira, Humberto d'Muniz
Source: Biochimie. Unidade: IFSC
Subjects: SCHISTOSOMA MANSONI, CRISTALOGRAFIA, BIOQUÍMICA, ESQUISTOSSOMOSE
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ABNT
SILVA NETO, Antônio Marinho da et al. Analysis of two Schistosoma mansoni uridine phosphorylases isoforms suggests the emergence of a protein with a non-canonical function. Biochimie, v. 125, p. 12-22, 2016Tradução . . Disponível em: https://doi.org/10.1016/j.biochi.2016.02.007. Acesso em: 06 nov. 2024.
APA
Silva Neto, A. M. da, Souza, J. R. T. de, Romanello, L., Cassago, A., Serrão, V. H. B., De Marco, R., et al. (2016). Analysis of two Schistosoma mansoni uridine phosphorylases isoforms suggests the emergence of a protein with a non-canonical function. Biochimie, 125, 12-22. doi:10.1016/j.biochi.2016.02.007
NLM
Silva Neto AM da, Souza JRT de, Romanello L, Cassago A, Serrão VHB, De Marco R, Brandão-Neto J, Garratt RC, Pereira H d'M. Analysis of two Schistosoma mansoni uridine phosphorylases isoforms suggests the emergence of a protein with a non-canonical function [Internet]. Biochimie. 2016 ; 125 12-22.[citado 2024 nov. 06 ] Available from: https://doi.org/10.1016/j.biochi.2016.02.007
Vancouver
Silva Neto AM da, Souza JRT de, Romanello L, Cassago A, Serrão VHB, De Marco R, Brandão-Neto J, Garratt RC, Pereira H d'M. Analysis of two Schistosoma mansoni uridine phosphorylases isoforms suggests the emergence of a protein with a non-canonical function [Internet]. Biochimie. 2016 ; 125 12-22.[citado 2024 nov. 06 ] Available from: https://doi.org/10.1016/j.biochi.2016.02.007
Artigo de periodico
Design, synthesis and biological evaluation of hybrid bioisoster derivatives of N-acylhydrazone and furoxan groups with potential and selective anti-Trypanosoma cruzi activity (2014)
Serafim, Ricardo Augusto Massarico; Gonçalves, José Eduardo; Souza, Felipe Pereira de; Loureiro, Ana Paula de Melo ; Storpirtis, Silvia ; Krogh, Renata; Andricopulo, Adriano Defini ; Dias, Luiz Carlos; Ferreira, Elizabeth Igne
Source: European Journal of Medicinal Chemistry. Unidades: FCF, IFSC
Subjects: TRYPANOSOMA CRUZI, INIBIDORES DE ENZIMAS, PLANEJAMENTO DE FÁRMACOS
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ABNT
SERAFIM, Ricardo Augusto Massarico et al. Design, synthesis and biological evaluation of hybrid bioisoster derivatives of N-acylhydrazone and furoxan groups with potential and selective anti-Trypanosoma cruzi activity. European Journal of Medicinal Chemistry, v. 82, p. 418-425, 2014Tradução . . Disponível em: https://doi.org/10.1016/j.ejmech.2014.05.077. Acesso em: 06 nov. 2024.
APA
Serafim, R. A. M., Gonçalves, J. E., Souza, F. P. de, Loureiro, A. P. de M., Storpirtis, S., Krogh, R., et al. (2014). Design, synthesis and biological evaluation of hybrid bioisoster derivatives of N-acylhydrazone and furoxan groups with potential and selective anti-Trypanosoma cruzi activity. European Journal of Medicinal Chemistry, 82, 418-425. doi:10.1016/j.ejmech.2014.05.077
NLM
Serafim RAM, Gonçalves JE, Souza FP de, Loureiro AP de M, Storpirtis S, Krogh R, Andricopulo AD, Dias LC, Ferreira EI. Design, synthesis and biological evaluation of hybrid bioisoster derivatives of N-acylhydrazone and furoxan groups with potential and selective anti-Trypanosoma cruzi activity [Internet]. European Journal of Medicinal Chemistry. 2014 ; 82 418-425.[citado 2024 nov. 06 ] Available from: https://doi.org/10.1016/j.ejmech.2014.05.077
Vancouver
Serafim RAM, Gonçalves JE, Souza FP de, Loureiro AP de M, Storpirtis S, Krogh R, Andricopulo AD, Dias LC, Ferreira EI. Design, synthesis and biological evaluation of hybrid bioisoster derivatives of N-acylhydrazone and furoxan groups with potential and selective anti-Trypanosoma cruzi activity [Internet]. European Journal of Medicinal Chemistry. 2014 ; 82 418-425.[citado 2024 nov. 06 ] Available from: https://doi.org/10.1016/j.ejmech.2014.05.077

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