Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors (2021)
- Authors:
- USP affiliated authors: GUIDO, RAFAEL VICTÓRIO CARVALHO - IFSC ; JABOR, VALQUÍRIA APARECIDA POLISEL - FCFRP ; NONATO, MARIA CRISTINA - FCFRP ; SOUZA, JULIANA OLIVEIRA DE - IFSC ; AGUIAR, ANNA CAROLINE CAMPOS - IFSC
- Unidades: IFSC; FCFRP
- DOI: 10.1016/j.ejmech.2020.112941
- Subjects: ANTIMALÁRICOS; ANTIPARASITÁRIOS; MALÁRIA
- Keywords: Triazolopyrimidine; Pyrazolopyrimidine; Quinoline; Malaria; P. falciparum; PfDHODH
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Publisher place: Issy-les-Moulineaux
- Date published: 2021
- Source:
- Título: European Journal of Medicinal Chemistry
- ISSN: 0223-5234
- Volume/Número/Paginação/Ano: v. 209, p. 112941-1-112941-16, Jan. 2021
- Este periódico é de acesso aberto
- Este artigo NÃO é de acesso aberto
-
ABNT
SILVEIRA, Flávia F. et al. Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors. European Journal of Medicinal Chemistry, v. 209, n. Ja 2021, p. 112941-1-112941-16, 2021Tradução . . Disponível em: https://doi.org/10.1016/j.ejmech.2020.112941. Acesso em: 04 mar. 2026. -
APA
Silveira, F. F., Souza, J. O. de, Hoelz, L. V. B., Campos, V. R., Jabor, V. A. P., Aguiar, A. C. C., et al. (2021). Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors. European Journal of Medicinal Chemistry, 209( Ja 2021), 112941-1-112941-16. doi:10.1016/j.ejmech.2020.112941 -
NLM
Silveira FF, Souza JO de, Hoelz LVB, Campos VR, Jabor VAP, Aguiar ACC, Nonato MC, Albuquerque MG, Guido RVC, Boechat N, Pinheiro LCS. Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors [Internet]. European Journal of Medicinal Chemistry. 2021 ; 209( Ja 2021): 112941-1-112941-16.[citado 2026 mar. 04 ] Available from: https://doi.org/10.1016/j.ejmech.2020.112941 -
Vancouver
Silveira FF, Souza JO de, Hoelz LVB, Campos VR, Jabor VAP, Aguiar ACC, Nonato MC, Albuquerque MG, Guido RVC, Boechat N, Pinheiro LCS. Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors [Internet]. European Journal of Medicinal Chemistry. 2021 ; 209( Ja 2021): 112941-1-112941-16.[citado 2026 mar. 04 ] Available from: https://doi.org/10.1016/j.ejmech.2020.112941 - New pyrazolopyrimidine and triazolopyrimidine derivatives with potential activity anti-P. falciparum
- Syntesis [i. e. synthesis] of new hydrazones triazololopyrimidines derivatives as antiplasmodium agents
- Discovery of antimalarial azetidine-2-carbonitriles that inhibit P. falciparum dihydroorotate dehydrogenase
- Evaluation of 7-arylaminopyrazolo[1,5- a ]pyrimidines as anti- Plasmodium falciparum , antimalarial, and Pf- dihydroorotate dehydrogenase inhibitors
- Synthesis and biological evaluation of natural-product-inspired, aminoalkyl-substituted 1-benzopyrans as novel antiplasmodial agents
- Descoberta de derivados 4-quinolinonas como candidatos a fármacos antimaláricos: caracterização da atividade antiplasmodial in vitro, ex vivo e estudo de mecanismo de ação
- Aryl benzimidazoles: a new lead in malaria drug discovery
- Potent antimalarials with development potential identified by structure-guided computational optimization of a pyrrole-based dihydroorotate dehydrogenase inhibitor series
- Repositioning and characterization of 1‑(Pyridin-4-yl)pyrrolidin-2- one derivatives as plasmodium cytoplasmic prolyl-tRNA synthetase inhibitors
- [1-7-NαC]-Crocaorb A1 and A2, orbitides from the latex of Croton campanulatus
Informações sobre o DOI: 10.1016/j.ejmech.2020.112941 (Fonte: oaDOI API)
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