Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors (2021)
- Authors:
- USP affiliated authors: GUIDO, RAFAEL VICTÓRIO CARVALHO - IFSC ; JABOR, VALQUÍRIA APARECIDA POLISEL - FCFRP ; NONATO, MARIA CRISTINA - FCFRP ; SOUZA, JULIANA OLIVEIRA DE - IFSC ; AGUIAR, ANNA CAROLINE CAMPOS - IFSC
- Unidades: IFSC; FCFRP
- DOI: 10.1016/j.ejmech.2020.112941
- Subjects: ANTIMALÁRICOS; ANTIPARASITÁRIOS; MALÁRIA
- Keywords: Triazolopyrimidine; Pyrazolopyrimidine; Quinoline; Malaria; P. falciparum; PfDHODH
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Publisher place: Issy-les-Moulineaux
- Date published: 2021
- Source:
- Título: European Journal of Medicinal Chemistry
- ISSN: 0223-5234
- Volume/Número/Paginação/Ano: v. 209, p. 112941-1-112941-16, Jan. 2021
- Este periódico é de assinatura
- Este artigo NÃO é de acesso aberto
- Cor do Acesso Aberto: closed
-
ABNT
SILVEIRA, Flávia F. et al. Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors. European Journal of Medicinal Chemistry, v. 209, n. Ja 2021, p. 112941-1-112941-16, 2021Tradução . . Disponível em: https://doi.org/10.1016/j.ejmech.2020.112941. Acesso em: 08 jan. 2026. -
APA
Silveira, F. F., Souza, J. O. de, Hoelz, L. V. B., Campos, V. R., Jabor, V. A. P., Aguiar, A. C. C., et al. (2021). Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors. European Journal of Medicinal Chemistry, 209( Ja 2021), 112941-1-112941-16. doi:10.1016/j.ejmech.2020.112941 -
NLM
Silveira FF, Souza JO de, Hoelz LVB, Campos VR, Jabor VAP, Aguiar ACC, Nonato MC, Albuquerque MG, Guido RVC, Boechat N, Pinheiro LCS. Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors [Internet]. European Journal of Medicinal Chemistry. 2021 ; 209( Ja 2021): 112941-1-112941-16.[citado 2026 jan. 08 ] Available from: https://doi.org/10.1016/j.ejmech.2020.112941 -
Vancouver
Silveira FF, Souza JO de, Hoelz LVB, Campos VR, Jabor VAP, Aguiar ACC, Nonato MC, Albuquerque MG, Guido RVC, Boechat N, Pinheiro LCS. Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors [Internet]. European Journal of Medicinal Chemistry. 2021 ; 209( Ja 2021): 112941-1-112941-16.[citado 2026 jan. 08 ] Available from: https://doi.org/10.1016/j.ejmech.2020.112941 - Syntesis [i. e. synthesis] of new hydrazones triazololopyrimidines derivatives as antiplasmodium agents
- New pyrazolopyrimidine and triazolopyrimidine derivatives with potential activity anti-P. falciparum
- Descoberta de derivados 4-quinolinonas como candidatos a fármacos antimaláricos: caracterização da atividade antiplasmodial in vitro, ex vivo e estudo de mecanismo de ação
- Discovery of antimalarial azetidine-2-carbonitriles that inhibit P. falciparum dihydroorotate dehydrogenase
- Evaluation of 7-arylaminopyrazolo[1,5- a ]pyrimidines as anti- Plasmodium falciparum , antimalarial, and Pf- dihydroorotate dehydrogenase inhibitors
- Synthesis and biological evaluation of natural-product-inspired, aminoalkyl-substituted 1-benzopyrans as novel antiplasmodial agents
- Fighting Plasmodium chloroquine resistance with acetylenic chloroquine analogues
- Repositioning and characterization of 1‑(Pyridin-4-yl)pyrrolidin-2- one derivatives as plasmodium cytoplasmic prolyl-tRNA synthetase inhibitors
- Potent antimalarials with development potential identified by structure-guided computational optimization of a pyrrole-based dihydroorotate dehydrogenase inhibitor series
- Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome
Informações sobre o DOI: 10.1016/j.ejmech.2020.112941 (Fonte: oaDOI API)
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