Multiparametric optimization of pyrazole compounds with antimalarial activity (2025)
- Authors:
- USP affiliated authors: GUIDO, RAFAEL VICTÓRIO CARVALHO - IFSC ; AGUIAR, ANNA CAROLINE CAMPOS - IFSC ; MALUF, SARAH EL CHAMY - IFSC
- Unidade: IFSC
- Subjects: MALÁRIA; ANTIMALÁRICOS; CRISTALOGRAFIA; PLANEJAMENTO DE FÁRMACOS
- Keywords: Drug discovery; Hit-to-lead; Malaria; SAR
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Publisher: Universidade Federal do Rio de Janeiro - UFRJ
- Publisher place: Rio de Janeiro
- Date published: 2025
- Source:
- Título: Annals
- Conference titles: Brazilian Symposium on Medicinal Chemistry - BrazMedChem
-
ABNT
MEDEIROS, Natália Goedtel et al. Multiparametric optimization of pyrazole compounds with antimalarial activity. 2025, Anais.. Rio de Janeiro: Universidade Federal do Rio de Janeiro - UFRJ, 2025. Disponível em: https://repositorio.usp.br/directbitstream/6328b4a8-bf91-4b8f-b414-e1469cb959de/3290511.pdf. Acesso em: 30 mar. 2026. -
APA
Medeiros, N. G., Kumar, M., Ahmad, A., Aguiar, A. C. C., Maluf, S. E. C., Guido, R. V. C., et al. (2025). Multiparametric optimization of pyrazole compounds with antimalarial activity. In Annals. Rio de Janeiro: Universidade Federal do Rio de Janeiro - UFRJ. Recuperado de https://repositorio.usp.br/directbitstream/6328b4a8-bf91-4b8f-b414-e1469cb959de/3290511.pdf -
NLM
Medeiros NG, Kumar M, Ahmad A, Aguiar ACC, Maluf SEC, Guido RVC, Geldern TW von, Soldati-Favre D, Baudd D, Willis P, Chenu E, Duffy J, Dias LC. Multiparametric optimization of pyrazole compounds with antimalarial activity [Internet]. Annals. 2025 ;[citado 2026 mar. 30 ] Available from: https://repositorio.usp.br/directbitstream/6328b4a8-bf91-4b8f-b414-e1469cb959de/3290511.pdf -
Vancouver
Medeiros NG, Kumar M, Ahmad A, Aguiar ACC, Maluf SEC, Guido RVC, Geldern TW von, Soldati-Favre D, Baudd D, Willis P, Chenu E, Duffy J, Dias LC. Multiparametric optimization of pyrazole compounds with antimalarial activity [Internet]. Annals. 2025 ;[citado 2026 mar. 30 ] Available from: https://repositorio.usp.br/directbitstream/6328b4a8-bf91-4b8f-b414-e1469cb959de/3290511.pdf - Synthesis and optimization of indole-2-carboxamides for enhanced anti-plasmodial activity
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- Potent antimalarials with development potential identified by structure-guided computational optimization of a pyrrole-based dihydroorotate dehydrogenase inhibitor series
- Repositioning and characterization of 1‑(Pyridin-4-yl)pyrrolidin-2- one derivatives as plasmodium cytoplasmic prolyl-tRNA synthetase inhibitors
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