Identification of active small molecules targeting the endopeptidase RipA from Mycobacterium tuberculosis (2025)
- Authors:
- Silva, Catharina dos Santos
- Rodrigues, Vinícius Lopes Tarouquella
- Libreros-Zunigã, Gerardo Andrés
- Rossini, Nicolas de Oliveira
- Guterrez, Kevim Bordignon
- Barroso, Vinícius de Morais
- Mesquita, Nathalya Cristina de Moraes Roso
- Tinoco, Luzineide Wanderley
- Sforça, Maurício Luis
- Guimarães, Ana Marcia de Sá
- Ishida, Kelly
- Emery, Flavio da Silva
- Dias, Marcio Vinicius Bertacine
- Silva, Catharina dos Santos
- USP affiliated authors: GUIMARÃES, ANA MARCIA DE SÁ - ICB ; ISHIDA, KELLY - ICB ; EMERY, FLAVIO DA SILVA - FCFRP ; DIAS, MARCIO VINÍCIUS BERTACINE - ICB ; SILVA, CATHARINA DOS SANTOS - ICB ; RODRIGUES, VINÍCIUS LOPES TAROUQUELLA - FCFRP ; ROSSINI, NÍCOLAS DE OLIVEIRA - ICB ; GUTERRES, KEVIM BORDIGNON - FMVZ ; BARROSO, VINICIUS DE MORAIS - ICB ; MESQUITA, NATHALYA CRISTINA DE MORAES ROSO - IFSC
- Unidades: ICB; FCFRP; FMVZ; IFSC
- Subjects: TUBERCULOSE; RESSONÂNCIA MAGNÉTICA NUCLEAR; PESQUISA CIENTÍFICA; PLANEJAMENTO DE FÁRMACOS
- Keywords: Tuberculosis; Cell-wall hydrolase; Fragment-based drug discovery
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Publisher: Universidade Federal do Rio de Janeiro - UFRJ
- Publisher place: Rio de Janeiro
- Date published: 2025
- Source:
- Título: Annals
- Conference titles: Brazilian Symposium on Medicinal Chemistry - BrazMedChem
-
ABNT
SILVA, Catharina dos Santos et al. Identification of active small molecules targeting the endopeptidase RipA from Mycobacterium tuberculosis. 2025, Anais.. Rio de Janeiro: Universidade Federal do Rio de Janeiro - UFRJ, 2025. Disponível em: https://repositorio.usp.br/directbitstream/cfa531b1-fb7d-46da-821e-ef6370ef75c3/3290241.pdf. Acesso em: 01 abr. 2026. -
APA
Silva, C. dos S., Rodrigues, V. L. T., Libreros-Zunigã, G. A., Rossini, N. de O., Guterrez, K. B., Barroso, V. de M., et al. (2025). Identification of active small molecules targeting the endopeptidase RipA from Mycobacterium tuberculosis. In Annals. Rio de Janeiro: Universidade Federal do Rio de Janeiro - UFRJ. Recuperado de https://repositorio.usp.br/directbitstream/cfa531b1-fb7d-46da-821e-ef6370ef75c3/3290241.pdf -
NLM
Silva C dos S, Rodrigues VLT, Libreros-Zunigã GA, Rossini N de O, Guterrez KB, Barroso V de M, Mesquita NC de MR, Tinoco LW, Sforça ML, Guimarães AM de S, Ishida K, Emery F da S, Dias MVB. Identification of active small molecules targeting the endopeptidase RipA from Mycobacterium tuberculosis [Internet]. Annals. 2025 ;[citado 2026 abr. 01 ] Available from: https://repositorio.usp.br/directbitstream/cfa531b1-fb7d-46da-821e-ef6370ef75c3/3290241.pdf -
Vancouver
Silva C dos S, Rodrigues VLT, Libreros-Zunigã GA, Rossini N de O, Guterrez KB, Barroso V de M, Mesquita NC de MR, Tinoco LW, Sforça ML, Guimarães AM de S, Ishida K, Emery F da S, Dias MVB. Identification of active small molecules targeting the endopeptidase RipA from Mycobacterium tuberculosis [Internet]. Annals. 2025 ;[citado 2026 abr. 01 ] Available from: https://repositorio.usp.br/directbitstream/cfa531b1-fb7d-46da-821e-ef6370ef75c3/3290241.pdf - Using a fragment-based approach against a potential novel drug target in Mycobacterium tuberculosis
- The crystal structure of Mycobacterium thermoresistibile MurE ligase reveals the binding mode of the substrate m-diaminopimelate
- Crystal structure of dihydrofolate reductase from the emerging pathogenic fungus Candida auris
- The multiple roles of the NlpC_P60 peptidase family in mycobacteria: an underexplored target for antimicrobial drug discovery
- How to find a fragment: methods for screening and validation in fragment-based drug discovery
- Mutations and insights into the molecular mechanisms of resistance of Mycobacterium tuberculosis to first-line drugs
- Integration of biophysical and biological approaches to validate fragment-like compounds targeting l,d-transpeptidases from Mycobacterium tuberculosis
- Using cryo-electron microscopy to understand the mechanisms of antimicrobial resistance to DNA gyrase in Mycobacterium tuberculosis
- 2-aryloxazolines inhibit Candida clinical isolates growth and morphogenesis of Candida albicans and Candida tropicalis
- Bases estruturais do controle da elongação e da divisão celular em Mycobacterium tuberculosis e identificação de hits a fármacos baseada em triagem de fragmentos
Download do texto completo
| Tipo | Nome | Link | |
|---|---|---|---|
 |
3290241.pdf |
How to cite
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
