Using a fragment-based approach against a potential novel drug target in Mycobacterium tuberculosis (2025)
- Authors:
- Silva, Catharina dos Santos

- Rodrigues, Vinícius Lopes Tarouquella
- Libreros-Zunigã, Gerardo Andrés
- Rossini, Nicolas de Oliveira

- Guterrez, Kevim
- Barroso, Vinícius de Morais

- Mesquita, Nathalya Cristina de Moraes Roso

- Tinoco, Luzineide
- Sforça, Maurício Luis
- Guimarães, Ana Marcia de Sá

- Ishida, Kelly

- Emery, Flavio da Silva

- Dias, Marcio Vinicius Bertacine

- Silva, Catharina dos Santos
- USP affiliated authors: GUIMARÃES, ANA MARCIA DE SÁ - ICB ; ISHIDA, KELLY - ICB ; EMERY, FLAVIO DA SILVA - FCFRP ; DIAS, MARCIO VINÍCIUS BERTACINE - ICB ; SILVA, CATHARINA DOS SANTOS - ICB ; RODRIGUES, VINÍCIUS LOPES TAROUQUELLA - FCFRP ; ROSSINI, NÍCOLAS DE OLIVEIRA - ICB ; BARROSO, VINICIUS DE MORAIS - ICB ; MESQUITA, NATHALYA CRISTINA DE MORAES ROSO - IFSC
- Unidades: ICB; FCFRP; IFSC
- Subjects: TUBERCULOSE; PLANEJAMENTO DE FÁRMACOS; RESSONÂNCIA MAGNÉTICA NUCLEAR
- Keywords: Tuberculosis; Cell-wall hydrolase; Drug-discovery
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Publisher: Sociedade Brasileira de Bioquímica e Biologia Molecular - SBBq
- Publisher place: São Paulo
- Date published: 2025
- Source:
- Título: Livro de Resumos
- Conference titles: Annual Meeting of the Brazilian Society for Biochemistry and Molecular Biology - SBBq
-
ABNT
SILVA, Catharina dos Santos et al. Using a fragment-based approach against a potential novel drug target in Mycobacterium tuberculosis. 2025, Anais.. São Paulo: Sociedade Brasileira de Bioquímica e Biologia Molecular - SBBq, 2025. Disponível em: https://www2.sbbq.org.br/reuniao/2025/images/resumos.pdf. Acesso em: 10 fev. 2026. -
APA
Silva, C. dos S., Rodrigues, V. L. T., Libreros-Zunigã, G. A., Rossini, N. de O., Guterrez, K., Barroso, V. de M., et al. (2025). Using a fragment-based approach against a potential novel drug target in Mycobacterium tuberculosis. In Livro de Resumos. São Paulo: Sociedade Brasileira de Bioquímica e Biologia Molecular - SBBq. Recuperado de https://www2.sbbq.org.br/reuniao/2025/images/resumos.pdf -
NLM
Silva C dos S, Rodrigues VLT, Libreros-Zunigã GA, Rossini N de O, Guterrez K, Barroso V de M, Mesquita NC de MR, Tinoco L, Sforça ML, Guimarães AM de S, Ishida K, Emery F da S, Dias MVB. Using a fragment-based approach against a potential novel drug target in Mycobacterium tuberculosis [Internet]. Livro de Resumos. 2025 ;[citado 2026 fev. 10 ] Available from: https://www2.sbbq.org.br/reuniao/2025/images/resumos.pdf -
Vancouver
Silva C dos S, Rodrigues VLT, Libreros-Zunigã GA, Rossini N de O, Guterrez K, Barroso V de M, Mesquita NC de MR, Tinoco L, Sforça ML, Guimarães AM de S, Ishida K, Emery F da S, Dias MVB. Using a fragment-based approach against a potential novel drug target in Mycobacterium tuberculosis [Internet]. Livro de Resumos. 2025 ;[citado 2026 fev. 10 ] Available from: https://www2.sbbq.org.br/reuniao/2025/images/resumos.pdf - The crystal structure of Mycobacterium thermoresistibile MurE ligase reveals the binding mode of the substrate m-diaminopimelate
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- Integration of biophysical and biological approaches to validate fragment-like compounds targeting l,d-transpeptidases from Mycobacterium tuberculosis
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- Bases estruturais do controle da elongação e da divisão celular em Mycobacterium tuberculosis e identificação de hits a fármacos baseada em triagem de fragmentos
- Crystal structure of BtrK, a decarboxylase involved in the (S)-4-amino-2-hydroxybutyrate (AHBA) formation during butirosin biosynthesis
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