Fragment-based discovery and optimization of Zika virus NS3 helicase ligands as antiviral hit candidates (2026)
- Authors:
- USP affiliated authors: OLIVA, GLAUCIUS - IFSC ; GUIDO, RAFAEL VICTÓRIO CARVALHO - IFSC ; MESQUITA, NATHALYA CRISTINA DE MORAES ROSO - IFSC ; MORÃO, LUANA GALVÃO - IFSC ; DOLCI, ISABELA - IFSC ; FERNANDES, RAFAELA SACHETTO - IFSC
- Unidade: IFSC
- DOI: 10.1016/j.ejmech.2025.118521
- Subjects: ZIKA VÍRUS; PLANEJAMENTO DE FÁRMACOS; ANTIVIRAIS
- Keywords: Zika virus; NS3 helicase; Phenylurea derivatives; Antiviral drug design; RNA binding site inhibitors
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Publisher place: Issy-les-Moulineaux
- Date published: 2026
- Source:
- Título: European Journal of Medicinal Chemistry
- ISSN: 0223-5234
- Volume/Número/Paginação/Ano: v. 304, p. 118521-1-118521-18 + supplementary data, Feb. 2026
- Este periódico é de acesso aberto
- Este artigo NÃO é de acesso aberto
-
ABNT
VIDAL, Hérika Danielle Almeida et al. Fragment-based discovery and optimization of Zika virus NS3 helicase ligands as antiviral hit candidates. European Journal of Medicinal Chemistry, v. 304, p. 118521-1-118521-18 + supplementary data, 2026Tradução . . Disponível em: https://doi.org/10.1016/j.ejmech.2025.118521. Acesso em: 25 jan. 2026. -
APA
Vidal, H. D. A., Mesquita, N. C. de M. R., Bernardes, A. C. B., Mourão, P. S., Monteiro, J. L., Morão, L. G., et al. (2026). Fragment-based discovery and optimization of Zika virus NS3 helicase ligands as antiviral hit candidates. European Journal of Medicinal Chemistry, 304, 118521-1-118521-18 + supplementary data. doi:10.1016/j.ejmech.2025.118521 -
NLM
Vidal HDA, Mesquita NC de MR, Bernardes ACB, Mourão PS, Monteiro JL, Morão LG, Dolci I, Fernandes RS, Oliva G, Guido RVC, Corrêa AG. Fragment-based discovery and optimization of Zika virus NS3 helicase ligands as antiviral hit candidates [Internet]. European Journal of Medicinal Chemistry. 2026 ; 304 118521-1-118521-18 + supplementary data.[citado 2026 jan. 25 ] Available from: https://doi.org/10.1016/j.ejmech.2025.118521 -
Vancouver
Vidal HDA, Mesquita NC de MR, Bernardes ACB, Mourão PS, Monteiro JL, Morão LG, Dolci I, Fernandes RS, Oliva G, Guido RVC, Corrêa AG. Fragment-based discovery and optimization of Zika virus NS3 helicase ligands as antiviral hit candidates [Internet]. European Journal of Medicinal Chemistry. 2026 ; 304 118521-1-118521-18 + supplementary data.[citado 2026 jan. 25 ] Available from: https://doi.org/10.1016/j.ejmech.2025.118521 - Synthesis of oxadiazole and hydantoin derivatives as potential zika virus NS3 helicase inhibitors
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Informações sobre o DOI: 10.1016/j.ejmech.2025.118521 (Fonte: oaDOI API)
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