Effects of decrease in Klotho protein expression on insulin signaling and levels of proteins related to brain energy metabolism (2025)
- Authors:
- USP affiliated authors: LIMA, LARISSA DE SÁ - ICB ; IWASHE, ELISA MITIKO KAWAMOTO - ICB ; SCAVONE, CRISTOFORO - ICB ; ORELLANA, ANA MARIA MARQUES - ICB ; MAZUCANTI, CAIO HENRIQUE YOKOYAMA - ICB ; Andreotti, Diana Zukas - ICB
- Unidade: ICB
- DOI: 10.1016/j.ejphar.2025.177587
- Subjects: FARMACOLOGIA; ENVELHECIMENTO CELULAR; METABOLISMO ENERGÉTICO; INSULINA; CAMUNDONGOS; TRANSDUÇÃO DE SINAL CELULAR; PROTEÍNAS; HIPOCAMPU DE ANIMAL
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Publisher place: Amasterdam
- Date published: 2025
- Source:
- Título: European Journal of Pharmacology
- ISSN: 1879-0712
- Volume/Número/Paginação/Ano: v. 997, art. 177587, 2025
- Status:
- Nenhuma versão em acesso aberto identificada
-
ABNT
ORELLANA, Ana Maria Marques et al. Effects of decrease in Klotho protein expression on insulin signaling and levels of proteins related to brain energy metabolism. European Journal of Pharmacology, v. 997, 2025Tradução . . Disponível em: https://doi.org/10.1016/j.ejphar.2025.177587. Acesso em: 31 mar. 2026. -
APA
Orellana, A. M. M., Mazucanti, C. H. Y., Andreotti, D. Z., Lima, L. de S., Kawamoto, E. M., & Scavone, C. (2025). Effects of decrease in Klotho protein expression on insulin signaling and levels of proteins related to brain energy metabolism. European Journal of Pharmacology, 997. doi:10.1016/j.ejphar.2025.177587 -
NLM
Orellana AMM, Mazucanti CHY, Andreotti DZ, Lima L de S, Kawamoto EM, Scavone C. Effects of decrease in Klotho protein expression on insulin signaling and levels of proteins related to brain energy metabolism [Internet]. European Journal of Pharmacology. 2025 ; 997[citado 2026 mar. 31 ] Available from: https://doi.org/10.1016/j.ejphar.2025.177587 -
Vancouver
Orellana AMM, Mazucanti CHY, Andreotti DZ, Lima L de S, Kawamoto EM, Scavone C. Effects of decrease in Klotho protein expression on insulin signaling and levels of proteins related to brain energy metabolism [Internet]. European Journal of Pharmacology. 2025 ; 997[citado 2026 mar. 31 ] Available from: https://doi.org/10.1016/j.ejphar.2025.177587 - Klotho increases antioxidant defenses in astrocytes and ubiquitin–proteasome activity in neurons
- Activity-dependent neuronal Klotho enhances astrocytic aerobic glycolysis
- Efeitos da proteína Klotho sobre a sinalização de insulina e metabolismo energético no sistema nervoso central
- Sinalização intracelular desencadeada por concentrações subtóxicas de estreptozotocina em células neuro-2A: modelo in vitro de neurodegeneração associada à doença de Alzheimer
- Insulin and autophagy in neurodegeneration
- Neuroprotective action of α-Klotho against LPS-activated glia conditioned medium in primary neuronal culture
- Alpha 2 Na+,K+-ATPase silencing induces loss of inflammatory response and ouabain protection in glial cells
- Sex-dependent changes in AMPAR expression and Na, K-ATPase activity in the cerebellum and hippocampus of α-Klotho-Hypomorphic mice
- Toll-like receptor 4 signaling is critical for the adaptive cellular stress response effects induced by intermittent fasting in the mouse brain
- Evaluation of the neuroprotective potential of benzylidene digoxin 15 against oxidative stress in a neuroinflammation models induced by lipopolysaccharide and on neuronal differentiation of hippocampal neural precursor cells
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