Evaluation of the neuroprotective potential of benzylidene digoxin 15 against oxidative stress in a neuroinflammation models induced by lipopolysaccharide and on neuronal differentiation of hippocampal neural precursor cells (2025)
- Authors:
- Cordeiro, Gilvânia A.
- Faria, Jessica A.
- Anjos, Leticia Pavan dos
- Garcia, Israel José Pereira
- Neves, Eduarda P. F. I.
- Lima, Gustavo Fernando de Frazão
- Campos, Hericle Mesquita
- Ferreira, Pâmela Y.
- Ghedini, Paulo C.
- Lima, Maira C.
- Villar, José Augusto Ferreira Perez
- Orellana, Ana Maria Marques
- Barbosa, Leandro Augusto De Oliveira
- Leite, Jacqueline Alves
- Santos, Hérica de Lima
- Scavone, Cristoforo
- Kawamoto, Elisa Mitiko
- USP affiliated authors: SCAVONE, CRISTOFORO - ICB ; IWASHE, ELISA MITIKO KAWAMOTO - ICB ; ORELLANA, ANA MARIA MARQUES - ICB ; ANJOS, LETÍCIA PAVAN DOS - ICB
- Unidade: ICB
- DOI: 10.3389/fphar.2025.1537720
- Subjects: FARMACOLOGIA; CEREBELO; ESTRESSE OXIDATIVO; ANTIOXIDANTES; COMPORTAMENTO ANIMAL; RATOS WISTAR; CAMUNDONGOS; SUPERÓXIDO DISMUTASE; HIPOCAMPU DE ANIMAL; LIPOPOLISSACARÍDEOS; CÓRTEX PRÉ-FRONTAL
- Agências de fomento:
- Financiamento Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (PNPDCAPES) e pelo CNPq
- Financiamento FAPESP
- Financiamento pelo CNPq
- Financiamento FINEP [Financiadora de Estudos e Projetos]
- Financiamento CAPES
- Financiamento Universidade Federal de Goiás - UFG
- Financiamento Fundação de Amparo à Pesquisa do Estado de Minas Gerais
- Financiamento FAPMIG
- Language: Inglês
- Imprenta:
- Source:
- Título: Frontiers in Pharmacology
- ISSN: 1663-9812
- Volume/Número/Paginação/Ano: v. 16, art. 1537720, 17 p., 2025
- Status:
- Artigo publicado em periódico de acesso aberto (Gold Open Access)
- Versão do Documento:
- Versão publicada (Published version)
- Acessar versão aberta:
-
ABNT
CORDEIRO, Gilvânia A. et al. Evaluation of the neuroprotective potential of benzylidene digoxin 15 against oxidative stress in a neuroinflammation models induced by lipopolysaccharide and on neuronal differentiation of hippocampal neural precursor cells. Frontiers in Pharmacology, v. 16, p. 17 , 2025Tradução . . Disponível em: https://doi.org/10.3389/fphar.2025.1537720. Acesso em: 31 mar. 2026. -
APA
Cordeiro, G. A., Faria, J. A., Anjos, L. P. dos, Garcia, I. J. P., Neves, E. P. F. I., Lima, G. F. de F., et al. (2025). Evaluation of the neuroprotective potential of benzylidene digoxin 15 against oxidative stress in a neuroinflammation models induced by lipopolysaccharide and on neuronal differentiation of hippocampal neural precursor cells. Frontiers in Pharmacology, 16, 17 . doi:10.3389/fphar.2025.1537720 -
NLM
Cordeiro GA, Faria JA, Anjos LP dos, Garcia IJP, Neves EPFI, Lima GF de F, Campos HM, Ferreira PY, Ghedini PC, Lima MC, Villar JAFP, Orellana AMM, Barbosa LADO, Leite JA, Santos H de L, Scavone C, Kawamoto EM. Evaluation of the neuroprotective potential of benzylidene digoxin 15 against oxidative stress in a neuroinflammation models induced by lipopolysaccharide and on neuronal differentiation of hippocampal neural precursor cells [Internet]. Frontiers in Pharmacology. 2025 ; 16 17 .[citado 2026 mar. 31 ] Available from: https://doi.org/10.3389/fphar.2025.1537720 -
Vancouver
Cordeiro GA, Faria JA, Anjos LP dos, Garcia IJP, Neves EPFI, Lima GF de F, Campos HM, Ferreira PY, Ghedini PC, Lima MC, Villar JAFP, Orellana AMM, Barbosa LADO, Leite JA, Santos H de L, Scavone C, Kawamoto EM. Evaluation of the neuroprotective potential of benzylidene digoxin 15 against oxidative stress in a neuroinflammation models induced by lipopolysaccharide and on neuronal differentiation of hippocampal neural precursor cells [Internet]. Frontiers in Pharmacology. 2025 ; 16 17 .[citado 2026 mar. 31 ] Available from: https://doi.org/10.3389/fphar.2025.1537720 - Klotho increases antioxidant defenses in astrocytes and ubiquitin–proteasome activity in neurons
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