Molecular docking and quantitative structureactivity relationships for a series of Trypanosoma cruzi dihydroorotate dehydrogenase inhibitors (2025)
- Authors:
- USP affiliated authors: ANDRICOPULO, ADRIANO DEFINI - IFSC ; FERREIRA, LEONARDO LUIZ GOMES - IFSC
- Unidade: IFSC
- DOI: 10.1590/s2175-97902025e24064
- Subjects: TRYPANOSOMA CRUZI; MODELAGEM MOLECULAR; DOENÇA DE CHAGAS; PLANEJAMENTO DE FÁRMACOS; QUÍMICA MÉDICA
- Keywords: Trypanosoma cruzi; Medicinal chemistry; QSAR; Dihydroorotate dehydrogenase; Inhibitors; Chagas disease
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Source:
- Título: Brazilian Journal of Pharmaceutical Sciences
- ISSN: 1984-8250
- Volume/Número/Paginação/Ano: v. 61, p. e24064-1-e24064-28, 2025
- Status:
- Artigo publicado em periódico de acesso aberto (Gold Open Access)
- Versão do Documento:
- Versão publicada (Published version)
- Acessar versão aberta:
-
ABNT
JESUS, Gabriela Cifelli de et al. Molecular docking and quantitative structureactivity relationships for a series of Trypanosoma cruzi dihydroorotate dehydrogenase inhibitors. Brazilian Journal of Pharmaceutical Sciences, v. 61, p. e24064-1-e24064-28, 2025Tradução . . Disponível em: https://doi.org/10.1590/s2175-97902025e24064. Acesso em: 16 abr. 2026. -
APA
Jesus, G. C. de, Ribeiro, T. S., Andricopulo, A. D., & Ferreira, L. L. G. (2025). Molecular docking and quantitative structureactivity relationships for a series of Trypanosoma cruzi dihydroorotate dehydrogenase inhibitors. Brazilian Journal of Pharmaceutical Sciences, 61, e24064-1-e24064-28. doi:10.1590/s2175-97902025e24064 -
NLM
Jesus GC de, Ribeiro TS, Andricopulo AD, Ferreira LLG. Molecular docking and quantitative structureactivity relationships for a series of Trypanosoma cruzi dihydroorotate dehydrogenase inhibitors [Internet]. Brazilian Journal of Pharmaceutical Sciences. 2025 ; 61 e24064-1-e24064-28.[citado 2026 abr. 16 ] Available from: https://doi.org/10.1590/s2175-97902025e24064 -
Vancouver
Jesus GC de, Ribeiro TS, Andricopulo AD, Ferreira LLG. Molecular docking and quantitative structureactivity relationships for a series of Trypanosoma cruzi dihydroorotate dehydrogenase inhibitors [Internet]. Brazilian Journal of Pharmaceutical Sciences. 2025 ; 61 e24064-1-e24064-28.[citado 2026 abr. 16 ] Available from: https://doi.org/10.1590/s2175-97902025e24064 - Novel brominated vinylic fatty acids effectively inhibit the leishmania topoisomerase IB enzyme mediated by halogen bond formation
- 3D QSAR studies for a series of Trypanosoma cruzi dehydrogenase inhibitors
- COVID-19: small-molecule clinical trials landscape [Editorial]
- Cancer estimates in Brazil reveal progress for the most lethal malignancies [Editorial]
- In vitro leishmanicidal activity of novel N-arylspermidine derivatives
- Chemoinformatics approaches to structure- and ligand-based drug design
- Empowering neglected tropical disease drug discovery with translational medicinal chemistry. [Editorial]
- World chagas disease day and the new road map for neglected tropical diseases. [Editorial]
- Experimental and computational investigations on a series of drug candidates for Chagas disease
- Design, synthesis, and biological evaluation of aryldiazepane derivatives against Trypanosoma cruzi
Informações sobre a disponibilidade de versões do artigo em acesso aberto coletadas automaticamente via oaDOI API (Unpaywall).
Por se tratar de integração com serviço externo, podem existir diferentes versões do trabalho (como preprints ou postprints), que podem diferir da versão publicada.
Download do texto completo
| Tipo | Nome | Link | |
|---|---|---|---|
 |
PROD036849_3234316.pdf | Direct link |
How to cite
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
