Design, synthesis, and biological evaluation of aryldiazepane derivatives against Trypanosoma cruzi (2025)
- Authors:
- USP affiliated authors: ANDRICOPULO, ADRIANO DEFINI - IFSC ; FERREIRA, LEONARDO LUIZ GOMES - IFSC
- Unidade: IFSC
- Subjects: TRYPANOSOMA CRUZI; PLANEJAMENTO DE FÁRMACOS
- Keywords: Hit-to-lead optimization; Structure-activity relationship; Pharmacokinetics
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Publisher: Universidade Federal do Rio de Janeiro - UFRJ
- Publisher place: Rio de Janeiro
- Date published: 2025
- Source:
- Título: Annals
- Conference titles: Brazilian Symposium on Medicinal Chemistry - BrazMedChem
-
ABNT
OLIVEIRA, Douglas Davison da Silva et al. Design, synthesis, and biological evaluation of aryldiazepane derivatives against Trypanosoma cruzi. 2025, Anais.. Rio de Janeiro: Universidade Federal do Rio de Janeiro - UFRJ, 2025. Disponível em: https://repositorio.usp.br/directbitstream/7344ee7f-c4a0-43ec-9b61-cc9dda961b21/3290321.pdf. Acesso em: 02 mar. 2026. -
APA
Oliveira, D. D. da S., Resende, D. de M., Souza, R. M., Santos, G. A., Chelucci, R. C., Andricopulo, A. D., et al. (2025). Design, synthesis, and biological evaluation of aryldiazepane derivatives against Trypanosoma cruzi. In Annals. Rio de Janeiro: Universidade Federal do Rio de Janeiro - UFRJ. Recuperado de https://repositorio.usp.br/directbitstream/7344ee7f-c4a0-43ec-9b61-cc9dda961b21/3290321.pdf -
NLM
Oliveira DD da S, Resende D de M, Souza RM, Santos GA, Chelucci RC, Andricopulo AD, Ferreira LLG, Murta SMF, Rezende Junior C de O. Design, synthesis, and biological evaluation of aryldiazepane derivatives against Trypanosoma cruzi [Internet]. Annals. 2025 ;[citado 2026 mar. 02 ] Available from: https://repositorio.usp.br/directbitstream/7344ee7f-c4a0-43ec-9b61-cc9dda961b21/3290321.pdf -
Vancouver
Oliveira DD da S, Resende D de M, Souza RM, Santos GA, Chelucci RC, Andricopulo AD, Ferreira LLG, Murta SMF, Rezende Junior C de O. Design, synthesis, and biological evaluation of aryldiazepane derivatives against Trypanosoma cruzi [Internet]. Annals. 2025 ;[citado 2026 mar. 02 ] Available from: https://repositorio.usp.br/directbitstream/7344ee7f-c4a0-43ec-9b61-cc9dda961b21/3290321.pdf - Novel brominated vinylic fatty acids effectively inhibit the leishmania topoisomerase IB enzyme mediated by halogen bond formation
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