Celastrol: a lead compound that inhibits SARS-CoV-2 replication, the activity of viral and human cysteine proteases, and virus-induced IL-6 secretion (2022)
- Authors:
- Fuzo, Carlos Alessandro
- Martins Júnior, Ronaldo Bragança
- Fraga-Silva, Thais Fernanda de Campos
- Amstalden, Martin Krähenbühl
- Leo, Thais Canassa de

- Souza, Juliano P.
- Lima, Thais Melquiades de
- Faccioli, Lucia Helena

- Okamoto, Débora Noma
- Juliano, Maria Aparecida
- França, Suzelei C.
- Juliano, Luiz
- Bonato, Vânia Luiza Deperon
- Arruda Neto, Eurico de
- Dias-Baruffi, Marcelo
- USP affiliated authors: MARTINS JUNIOR, RONALDO BRAGANÇA - FCFRP ; FACCIOLI, LUCIA HELENA - FCFRP ; BONATO, VANIA LUIZA DEPERON - FMRP ; ARRUDA NETO, EURICO DE - FMRP ; BARUFFI, MARCELO DIAS - FCFRP ; FUZO, CARLOS ALESSANDRO - FCFRP ; SILVA, THAIS FERNANDA DE CAMPOS FRAGA DA - FMRP ; AMSTALDEN, MARTIN KRÄHENBÜHL - FCFRP ; LÉO, THAÍS CANASSA DE - FCFRP ; LIMA, THAIS MELQUIADES DE - FMRP
- Unidades: FCFRP; FMRP
- DOI: 10.1002/ddr.21982
- Subjects: ANTIVIRAIS; COVID-19; CORONAVIRUS; INTERLEUCINA 6
- Keywords: Celastrol; COVID‐19; Cysteine protease inhibition; Molecular docking; SARS‐CoV‐2
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Source:
- Título: Drug Development Research
- ISSN: 0272-4391
- Volume/Número/Paginação/Ano: v. 83, n. 7, p. 1623-1640, 2022
- Este periódico é de assinatura
- Este artigo é de acesso aberto
- URL de acesso aberto
- Cor do Acesso Aberto: green
-
ABNT
FUZO, Carlos Alessandro et al. Celastrol: a lead compound that inhibits SARS-CoV-2 replication, the activity of viral and human cysteine proteases, and virus-induced IL-6 secretion. Drug Development Research, v. 83, n. 7, p. 1623-1640, 2022Tradução . . Disponível em: https://doi.org/10.1002/ddr.21982. Acesso em: 27 dez. 2025. -
APA
Fuzo, C. A., Martins Júnior, R. B., Fraga-Silva, T. F. de C., Amstalden, M. K., Leo, T. C. de, Souza, J. P., et al. (2022). Celastrol: a lead compound that inhibits SARS-CoV-2 replication, the activity of viral and human cysteine proteases, and virus-induced IL-6 secretion. Drug Development Research, 83( 7), 1623-1640. doi:10.1002/ddr.21982 -
NLM
Fuzo CA, Martins Júnior RB, Fraga-Silva TF de C, Amstalden MK, Leo TC de, Souza JP, Lima TM de, Faccioli LH, Okamoto DN, Juliano MA, França SC, Juliano L, Bonato VLD, Arruda Neto E de, Dias-Baruffi M. Celastrol: a lead compound that inhibits SARS-CoV-2 replication, the activity of viral and human cysteine proteases, and virus-induced IL-6 secretion [Internet]. Drug Development Research. 2022 ; 83( 7): 1623-1640.[citado 2025 dez. 27 ] Available from: https://doi.org/10.1002/ddr.21982 -
Vancouver
Fuzo CA, Martins Júnior RB, Fraga-Silva TF de C, Amstalden MK, Leo TC de, Souza JP, Lima TM de, Faccioli LH, Okamoto DN, Juliano MA, França SC, Juliano L, Bonato VLD, Arruda Neto E de, Dias-Baruffi M. Celastrol: a lead compound that inhibits SARS-CoV-2 replication, the activity of viral and human cysteine proteases, and virus-induced IL-6 secretion [Internet]. Drug Development Research. 2022 ; 83( 7): 1623-1640.[citado 2025 dez. 27 ] Available from: https://doi.org/10.1002/ddr.21982 - Discovering selected antibodies from deep-sequenced phage-display antibody library using ATTILA
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Informações sobre o DOI: 10.1002/ddr.21982 (Fonte: oaDOI API)
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