The PIP4K2 inhibitor THZ-P1-2 exhibits antileukemia activity by disruption of mitochondrial homeostasis and autophagy (2022)
- Authors:
- Lima, Keli
- Martins, Diego Antonio Pereira
- Miranda, Lívia Bassani Lins De
- Silva, Juan Luiz Coelho
- Leandro, Giovana da Silva
- Weinhäuser, Isabel
- Cavaglieri, Rita de Cássia
- Leal, Aline de Medeiros
- Silva, Wellington Fernandes da
- Lange, Ana Paula Alencar de Lima
- Velloso, Elvira Deolinda Rodrigues Pereira
- Rego, Eduardo Magalhães
- Griessinger, Emmanuel
- Hilberink, Jacobien R.
- Ammatuna, Emanuele
- Huls, Gerwin
- Schuringa, Jan Jacob
- Machado Neto, João Agostinho
- Lima, Keli
- USP affiliated authors: VELLOSO, ELVIRA DEOLINDA RODRIGUES PEREIRA - FM ; REGO, EDUARDO MAGALHÃES - FM ; MACHADO NETO, JOÃO AGOSTINHO - ICB ; LIMA, KELI CRISTINA DE - FM ; MARTINS, DIEGO ANTONIO PEREIRA - FMRP ; MIRANDA, LÍVIA BASSANI LINS DE - ICB ; LEANDRO, GIOVANA DA SILVA - ICB ; WEINHÄUSER, ISABEL - FMRP
- Unidades: FM; ICB; FMRP
- DOI: 10.1038/s41408-022-00747-w
- Subjects: FARMACOLOGIA; LEUCEMIA MIELOIDE AGUDA; HOMEOSTASE; APOPTOSE; MITOCÔNDRIAS; ESPECTROMETRIA DE MASSAS; CROMATOGRAFIA LÍQUIDA; CÉLULAS-TRONCO
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Source:
- Título: Blood Cancer Journal
- ISSN: 2044-5385
- Volume/Número/Paginação/Ano: v. 12, art. 151, p. 1-11, 2022
- Este periódico é de acesso aberto
- Este artigo é de acesso aberto
- URL de acesso aberto
- Cor do Acesso Aberto: gold
- Licença: cc-by
-
ABNT
LIMA, Keli et al. The PIP4K2 inhibitor THZ-P1-2 exhibits antileukemia activity by disruption of mitochondrial homeostasis and autophagy. Blood Cancer Journal, v. 12, p. 1-11, 2022Tradução . . Disponível em: https://doi.org/10.1038/s41408-022-00747-w. Acesso em: 27 dez. 2025. -
APA
Lima, K., Martins, D. A. P., Miranda, L. B. L. D., Silva, J. L. C., Leandro, G. da S., Weinhäuser, I., et al. (2022). The PIP4K2 inhibitor THZ-P1-2 exhibits antileukemia activity by disruption of mitochondrial homeostasis and autophagy. Blood Cancer Journal, 12, 1-11. doi:10.1038/s41408-022-00747-w -
NLM
Lima K, Martins DAP, Miranda LBLD, Silva JLC, Leandro G da S, Weinhäuser I, Cavaglieri R de C, Leal A de M, Silva WF da, Lange APA de L, Velloso EDRP, Rego EM, Griessinger E, Hilberink JR, Ammatuna E, Huls G, Schuringa JJ, Machado Neto JA. The PIP4K2 inhibitor THZ-P1-2 exhibits antileukemia activity by disruption of mitochondrial homeostasis and autophagy [Internet]. Blood Cancer Journal. 2022 ; 12 1-11.[citado 2025 dez. 27 ] Available from: https://doi.org/10.1038/s41408-022-00747-w -
Vancouver
Lima K, Martins DAP, Miranda LBLD, Silva JLC, Leandro G da S, Weinhäuser I, Cavaglieri R de C, Leal A de M, Silva WF da, Lange APA de L, Velloso EDRP, Rego EM, Griessinger E, Hilberink JR, Ammatuna E, Huls G, Schuringa JJ, Machado Neto JA. The PIP4K2 inhibitor THZ-P1-2 exhibits antileukemia activity by disruption of mitochondrial homeostasis and autophagy [Internet]. Blood Cancer Journal. 2022 ; 12 1-11.[citado 2025 dez. 27 ] Available from: https://doi.org/10.1038/s41408-022-00747-w - Targeting PIP4K2 lipid kinases through Thz-P1-2 reveals vulnerabilities related to mitochondrial homeostasis and autophagy in acute leukemia
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Informações sobre o DOI: 10.1038/s41408-022-00747-w (Fonte: oaDOI API)
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