Using a fragment-based approach to identify alternative chemical scaffolds targeting dihydrofolate reductase from Mycobacterium tuberculosis (2020)
- Authors:
- Ribeiro, João A.
- Hammer, Alexander

- Zuniga, Gerardo A. Libreros

- Pacheco, Sair Maximo Chavez

- Tyrakis, Petros

- Oliveira, Gabriel S. de
- Kirkman, Timothy

- Bakali, Jamal El

- Rocco, Silvana A.

- Sforça, Mauricio L.

- Parise Filho, Roberto

- Coyne, Anthony G.

- Blundell, Tom L.

- Abell, Chris

- Dias, Marcio Vinicius Bertacine

- USP affiliated authors: PARISE FILHO, ROBERTO - FCF ; DIAS, MARCIO VINÍCIUS BERTACINE - ICB
- Unidades: FCF; ICB
- DOI: 10.1021/acsinfecdis.0c00263
- Subjects: MYCOBACTERIUM TUBERCULOSIS; ÁCIDO FÓLICO; MICROBIOLOGIA; INIBIDORES DE ENZIMAS; ATIVAÇÃO ENZIMÁTICA
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Publisher place: Washington
- Date published: 2020
- Source:
- Título: ACS Infectious Diseases
- ISSN: 2373-8227
- Volume/Número/Paginação/Ano: v. 6, p. 2192−2201 : + Supplementary materials (p. S1-S16), 2020
- Status:
- Artigo possui versão em acesso aberto em repositório (Green Open Access)
- Versão do Documento:
- Versão publicada (Published version)
- Acessar versão aberta:
-
ABNT
RIBEIRO, João A. et al. Using a fragment-based approach to identify alternative chemical scaffolds targeting dihydrofolate reductase from Mycobacterium tuberculosis. ACS Infectious Diseases, v. 6, p. 2192−2201 : + Supplementary materials ( S1-S16), 2020Tradução . . Disponível em: https://doi.org/10.1021/acsinfecdis.0c00263. Acesso em: 01 abr. 2026. -
APA
Ribeiro, J. A., Hammer, A., Zuniga, G. A. L., Pacheco, S. M. C., Tyrakis, P., Oliveira, G. S. de, et al. (2020). Using a fragment-based approach to identify alternative chemical scaffolds targeting dihydrofolate reductase from Mycobacterium tuberculosis. ACS Infectious Diseases, 6, 2192−2201 : + Supplementary materials ( S1-S16). doi:10.1021/acsinfecdis.0c00263 -
NLM
Ribeiro JA, Hammer A, Zuniga GAL, Pacheco SMC, Tyrakis P, Oliveira GS de, Kirkman T, Bakali JE, Rocco SA, Sforça ML, Parise Filho R, Coyne AG, Blundell TL, Abell C, Dias MVB. Using a fragment-based approach to identify alternative chemical scaffolds targeting dihydrofolate reductase from Mycobacterium tuberculosis [Internet]. ACS Infectious Diseases. 2020 ; 6 2192−2201 : + Supplementary materials ( S1-S16).[citado 2026 abr. 01 ] Available from: https://doi.org/10.1021/acsinfecdis.0c00263 -
Vancouver
Ribeiro JA, Hammer A, Zuniga GAL, Pacheco SMC, Tyrakis P, Oliveira GS de, Kirkman T, Bakali JE, Rocco SA, Sforça ML, Parise Filho R, Coyne AG, Blundell TL, Abell C, Dias MVB. Using a fragment-based approach to identify alternative chemical scaffolds targeting dihydrofolate reductase from Mycobacterium tuberculosis [Internet]. ACS Infectious Diseases. 2020 ; 6 2192−2201 : + Supplementary materials ( S1-S16).[citado 2026 abr. 01 ] Available from: https://doi.org/10.1021/acsinfecdis.0c00263 - Optimization of new dihydrofolate reductase inhibitors of mycobacterium tuberculosis (mtDHFR): molecular docking, synthesis, evaluation of enzyme inhibition and antimycobacterial activity
- Structural basis of the selectivity of GenN, an Aminoglycoside N-Methyltransferase involved in gentamicin biosynthesis
- Fragment-Merging strategies with known pyrimidine scaffolds targeting dihydrofolate reductase from mycobacterium tuberculosis
- Mechanistic insights into dideoxygenation in gentamicin biosynthesis
- Cloning, expression, purification and biophysical analysis of two putative halogenases from the glycopeptide A47,934 gene cluster of Streptomyces toyocaensis
- Enzymology of pyran ring A formation in salinomycin biosynthesis
- Abordagem estrutural sobre biossínteses, alvos, estratégias de desenvolvimento e resistência a antimicrobianos
- Mycobacterial OtsA structures unveil substrate preference mechanism and allosteric regulation by 2-oxoglutarate and 2-phosphoglycerate
- Design, synthesis and biological activity of novel substituted 3-benzoic acid derivatives as MtDHFR inhibitors
- Mycobacterium tuberculosis dihydrofolate reductase inhibitors: State of Art Past 20 Years
Informações sobre a disponibilidade de versões do artigo em acesso aberto coletadas automaticamente via oaDOI API (Unpaywall).
Por se tratar de integração com serviço externo, podem existir diferentes versões do trabalho (como preprints ou postprints), que podem diferir da versão publicada.
How to cite
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
