PTEN loss in Gleason grade 7 prostate tumors exhibits intratumoral heterogeneity and is associated with unfavorable pathological features (2019)
- Authors:
- USP affiliated authors: SAGGIORO, FABIANO PINTO - SVOI ; SQUIRE, JEREMY ANDREW - FMRP ; REIS, RODOLFO BORGES DOS - FMRP ; ALBUQUERQUE, CLARISSA GONDIM PICANÇO DE - FMRP ; VIDOTTO, THIAGO - FMRP ; PEREIRA, CIRO SILVEIRA E - FMRP
- Unidades: SVOI; FMRP
- DOI: 10.1186/s41241-018-0071-y
- Subjects: NEOPLASIAS DOS GENITAIS MASCULINOS; ESCORE DO TESTE
- Keywords: PTEN; Digital pathology; Prostate cancer; Intratumoral heterogeneity; Fluorescence in situ hybridization; Immunohistochemistry
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Source:
- Título: Applied Cancer Research
- ISSN: 1980-5578
- Volume/Número/Paginação/Ano: v. 39, art. 1, 2019
- Status:
- Artigo aberto em periódico híbrido (Hybrid Open Access)
- Versão do Documento:
- Versão publicada (Published version)
- Acessar versão aberta:
-
ABNT
ALBUQUERQUE, Clarissa Gondim Picanço de et al. PTEN loss in Gleason grade 7 prostate tumors exhibits intratumoral heterogeneity and is associated with unfavorable pathological features. Applied Cancer Research, v. 39, 2019Tradução . . Disponível em: https://doi.org/10.1186/s41241-018-0071-y. Acesso em: 15 abr. 2026. -
APA
Albuquerque, C. G. P. de, Vidotto, T., Pereira, C. S., Saggioro, F. P., Jamaspishvili, T., Koti, M., et al. (2019). PTEN loss in Gleason grade 7 prostate tumors exhibits intratumoral heterogeneity and is associated with unfavorable pathological features. Applied Cancer Research, 39. doi:10.1186/s41241-018-0071-y -
NLM
Albuquerque CGP de, Vidotto T, Pereira CS, Saggioro FP, Jamaspishvili T, Koti M, Berman DM, Squire JA, Reis RB dos. PTEN loss in Gleason grade 7 prostate tumors exhibits intratumoral heterogeneity and is associated with unfavorable pathological features [Internet]. Applied Cancer Research. 2019 ; 39[citado 2026 abr. 15 ] Available from: https://doi.org/10.1186/s41241-018-0071-y -
Vancouver
Albuquerque CGP de, Vidotto T, Pereira CS, Saggioro FP, Jamaspishvili T, Koti M, Berman DM, Squire JA, Reis RB dos. PTEN loss in Gleason grade 7 prostate tumors exhibits intratumoral heterogeneity and is associated with unfavorable pathological features [Internet]. Applied Cancer Research. 2019 ; 39[citado 2026 abr. 15 ] Available from: https://doi.org/10.1186/s41241-018-0071-y - PTEN‐deficient prostate cancer is associated with an immunosuppressive tumor microenvironment mediated by increased expression of IDO1 and infiltrating FoxP3+ T regulatory cells
- Loss of heterozygosity impacts MHC expression on the immune microenvironment in CDK12-mutated prostate cancer
- PTEN loss associates with STAT1/3 expression and intra-tumoral CD8+ density in prostate cancer
- Quantitative measurement of PTEN loss improves risk assessment in prostate cancer
- Risk stratification of prostate cancer through quantitative assessment of PTEN loss (qPTEN)
- Distinct subtypes of genomic PTEN deletion size influence the landscape of aneuploidy and outcome in prostate cancer
- Investigating the role of SNAI1 and ZEB1 expression in prostate cancer progression and immune modulation of the tumor microenvironment
- Epithelial–mesenchymal transition signaling and prostate cancer stem cells: emerging biomarkers and opportunities for precision therapeutics
- Impacto de polimorfismos cromossômicos de heterocromatina na meiose masculina humana
- Frequência de aneuploidias em células germinativas de homens fumantes
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