Loss of heterozygosity impacts MHC expression on the immune microenvironment in CDK12-mutated prostate cancer (2024)
- Authors:
- USP affiliated authors: SAGGIORO, FABIANO PINTO - FMRP ; REIS, RODOLFO BORGES DOS - FMRP ; SQUIRE, JEREMY ANDREW - FMRP
- Unidade: FMRP
- DOI: 10.1186/s13039-024-00680-6
- Subjects: NEOPLASIAS; EPIGÊNESE GENÉTICA; PRÓSTATA; GENÔMICA; CÉLULAS
- Keywords: Somatic chromosomal alterations; Copy number associations; Biomarkers; Immunotherapy; Transcriptomics; Public domain databases; Digital cytometry; Antigen presentation; Immune evasion; Adaptative immune system
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Source:
- Título: Molecular Cytogenetics
- ISSN: 1755-8166
- Volume/Número/Paginação/Ano: v. 17, n. 1, art. 11, p. 1-19, 2024
- Este periódico é de acesso aberto
- Este artigo NÃO é de acesso aberto
-
ABNT
DUTRA, William Lautert et al. Loss of heterozygosity impacts MHC expression on the immune microenvironment in CDK12-mutated prostate cancer. Molecular Cytogenetics, v. 17, n. 1, p. 1-19, 2024Tradução . . Disponível em: https://doi.org/10.1186/s13039-024-00680-6. Acesso em: 25 fev. 2026. -
APA
Dutra, W. L., Melo, C. M., Chaves, L. P., Crozier, C., Saggioro, F. P., Reis, R. B. dos, et al. (2024). Loss of heterozygosity impacts MHC expression on the immune microenvironment in CDK12-mutated prostate cancer. Molecular Cytogenetics, 17( 1), 1-19. doi:10.1186/s13039-024-00680-6 -
NLM
Dutra WL, Melo CM, Chaves LP, Crozier C, Saggioro FP, Reis RB dos, Bayani J, Bonatto SL, Squire JA. Loss of heterozygosity impacts MHC expression on the immune microenvironment in CDK12-mutated prostate cancer [Internet]. Molecular Cytogenetics. 2024 ; 17( 1): 1-19.[citado 2026 fev. 25 ] Available from: https://doi.org/10.1186/s13039-024-00680-6 -
Vancouver
Dutra WL, Melo CM, Chaves LP, Crozier C, Saggioro FP, Reis RB dos, Bayani J, Bonatto SL, Squire JA. Loss of heterozygosity impacts MHC expression on the immune microenvironment in CDK12-mutated prostate cancer [Internet]. Molecular Cytogenetics. 2024 ; 17( 1): 1-19.[citado 2026 fev. 25 ] Available from: https://doi.org/10.1186/s13039-024-00680-6 - PTEN loss associates with STAT1/3 expression and intra-tumoral CD8+ density in prostate cancer
- Quantitative measurement of PTEN loss improves risk assessment in prostate cancer
- Risk stratification of prostate cancer through quantitative assessment of PTEN loss (qPTEN)
- Investigating the role of SNAI1 and ZEB1 expression in prostate cancer progression and immune modulation of the tumor microenvironment
- Epithelial–mesenchymal transition signaling and prostate cancer stem cells: emerging biomarkers and opportunities for precision therapeutics
- Precision oncology platforms: practical strategies for genomic database utilization in cancer treatment
- Emerging role of PTEN loss in evasion of the immune response to tumours
- Analysis of the relationships between ZEB1, PTEN loss, TMPRSS2-ERG fusion and immune response biomarkers in Prostate Cancer
- PTEN‐deficient prostate cancer is associated with an immunosuppressive tumor microenvironment mediated by increased expression of IDO1 and infiltrating FoxP3+ T regulatory cells
- PTEN loss in Gleason grade 7 prostate tumors exhibits intratumoral heterogeneity and is associated with unfavorable pathological features
Informações sobre o DOI: 10.1186/s13039-024-00680-6 (Fonte: oaDOI API)
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