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Artigo de periodico
A distinct DNA methylation shift in a subset of glioma CpG island methylator phenotypes during tumor recurrence (2018)
Souza, Camila Ferreira de; Sabedot, Thais S.; Malta, Tathiane M.; Stetson, Lindsay; Morozova, Olena; Sokolov, Artem; Laird, Peter W.; Wiznerowicz, Maciej; Iavarone, Antonio; Snyder, James; Carvalho, Ana de; Sanborn, Zachary; McDonald, Kerrie L.; Friedman, William A.; Tirapelli, Daniela Pretti da Cunha; Poisson, Laila; Mikkelsen, Tom; Carlotti Júnior, Carlos Gilberto; Kalkanis, Steven; Zenklusen, Jean; Salama, Sofie R.; Barnholtz-Sloan, Jill S.; Noushmehr, Houtan
Source: Cell Reports. Unidade: FMRP
Subjects: METILAÇÃO DE DNA, BIOMARCADORES, GLIOMA
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ABNT
SOUZA, Camila Ferreira de et al. A distinct DNA methylation shift in a subset of glioma CpG island methylator phenotypes during tumor recurrence. Cell Reports, v. 23, n. 2, p. 637-651, 2018Tradução . . Disponível em: https://doi.org/10.1016/j.celrep.2018.03.107. Acesso em: 01 nov. 2025.
APA
Souza, C. F. de, Sabedot, T. S., Malta, T. M., Stetson, L., Morozova, O., Sokolov, A., et al. (2018). A distinct DNA methylation shift in a subset of glioma CpG island methylator phenotypes during tumor recurrence. Cell Reports, 23( 2), 637-651. doi:10.1016/j.celrep.2018.03.107
NLM
Souza CF de, Sabedot TS, Malta TM, Stetson L, Morozova O, Sokolov A, Laird PW, Wiznerowicz M, Iavarone A, Snyder J, Carvalho A de, Sanborn Z, McDonald KL, Friedman WA, Tirapelli DP da C, Poisson L, Mikkelsen T, Carlotti Júnior CG, Kalkanis S, Zenklusen J, Salama SR, Barnholtz-Sloan JS, Noushmehr H. A distinct DNA methylation shift in a subset of glioma CpG island methylator phenotypes during tumor recurrence [Internet]. Cell Reports. 2018 ; 23( 2): 637-651.[citado 2025 nov. 01 ] Available from: https://doi.org/10.1016/j.celrep.2018.03.107
Vancouver
Souza CF de, Sabedot TS, Malta TM, Stetson L, Morozova O, Sokolov A, Laird PW, Wiznerowicz M, Iavarone A, Snyder J, Carvalho A de, Sanborn Z, McDonald KL, Friedman WA, Tirapelli DP da C, Poisson L, Mikkelsen T, Carlotti Júnior CG, Kalkanis S, Zenklusen J, Salama SR, Barnholtz-Sloan JS, Noushmehr H. A distinct DNA methylation shift in a subset of glioma CpG island methylator phenotypes during tumor recurrence [Internet]. Cell Reports. 2018 ; 23( 2): 637-651.[citado 2025 nov. 01 ] Available from: https://doi.org/10.1016/j.celrep.2018.03.107
Artigo de periodico
Comparative molecular analysis of gastrointestinal adenocarcinomas (2018)
Liu, Yang; Sethi, Nilay S.; Hinoue, Toshinori; Schneider, Barbara G.; Cherniack , Andrew D.; Sanchez-Vega, Francisco; Seoane, Jose A.; Farshidfar, Farshad; Bowlby, Reanne; Islam, Mirazul; Kim, Jaegil; Chatila, Walid; Akbani, Rehan; Kanchi, Rupa S.; Rabkin, Charles S.; Willis, Joseph E.; Wang, Kenneth K.; McCall, Shannon J.; Mishra, Lopa; Ojesina, Akinyemi I.; Bullman, Susan; Pedamallu, Chandra Sekhar; Lazar, Alexander J.; Sakai, Ryo; Thorsson, Vésteinn; Bass, Adam J.; Laird, Peter W.; Carlotti Júnior, Carlos Gilberto; Santos, José Sebastião dos; Kemp, Rafael; Sankarankuty, Ajith Kumar; Tirapelli, Daniela Pretti da Cunha
Source: Cancer Cell. Unidade: FMRP
Subjects: ADENOCARCINOMA, GENÔMICA, METILAÇÃO DE DNA, NEOPLASIAS GASTROINTESTINAIS
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LIU, Yang et al. Comparative molecular analysis of gastrointestinal adenocarcinomas. Cancer Cell, v. 33, n. 4, p. 721-735, 2018Tradução . . Disponível em: https://doi.org/10.1016/j.ccell.2018.03.010. Acesso em: 01 nov. 2025.
APA
Liu, Y., Sethi, N. S., Hinoue, T., Schneider, B. G., Cherniack , A. D., Sanchez-Vega, F., et al. (2018). Comparative molecular analysis of gastrointestinal adenocarcinomas. Cancer Cell, 33( 4), 721-735. doi:10.1016/j.ccell.2018.03.010
NLM
Liu Y, Sethi NS, Hinoue T, Schneider BG, Cherniack AD, Sanchez-Vega F, Seoane JA, Farshidfar F, Bowlby R, Islam M, Kim J, Chatila W, Akbani R, Kanchi RS, Rabkin CS, Willis JE, Wang KK, McCall SJ, Mishra L, Ojesina AI, Bullman S, Pedamallu CS, Lazar AJ, Sakai R, Thorsson V, Bass AJ, Laird PW, Carlotti Júnior CG, Santos JS dos, Kemp R, Sankarankuty AK, Tirapelli DP da C. Comparative molecular analysis of gastrointestinal adenocarcinomas [Internet]. Cancer Cell. 2018 ; 33( 4): 721-735.[citado 2025 nov. 01 ] Available from: https://doi.org/10.1016/j.ccell.2018.03.010
Vancouver
Liu Y, Sethi NS, Hinoue T, Schneider BG, Cherniack AD, Sanchez-Vega F, Seoane JA, Farshidfar F, Bowlby R, Islam M, Kim J, Chatila W, Akbani R, Kanchi RS, Rabkin CS, Willis JE, Wang KK, McCall SJ, Mishra L, Ojesina AI, Bullman S, Pedamallu CS, Lazar AJ, Sakai R, Thorsson V, Bass AJ, Laird PW, Carlotti Júnior CG, Santos JS dos, Kemp R, Sankarankuty AK, Tirapelli DP da C. Comparative molecular analysis of gastrointestinal adenocarcinomas [Internet]. Cancer Cell. 2018 ; 33( 4): 721-735.[citado 2025 nov. 01 ] Available from: https://doi.org/10.1016/j.ccell.2018.03.010
Artigo de periodico
Genomic and molecular landscape of DNA damage repair deficiency across the cancer genome atlas (2018)
Knijnenburg, Theo A.; Wang, Linghua; Zimmermann, Michael T.; Chambwe, Nyasha; Gao, Galen F.; Cherniack , Andrew D.; Fan, Huihui; Shen, Hui; Way, Gregory P.; Greene, Casey S; Liu, Yuexin; Akbani, Rehan; Feng, Bin; Donehower, Lawrence A.; Miller, Chase; Shen, Yang; Karimi, Mostafa; Chen, Haoran; Kim, Pora; Jia, Peilin; Shinbrot, Eve; Zhang, Shaojun; Liu, Jianfang; Hu, Hai; Bailey, Matthew H.; Yau, Christina; Wolf, Denise M.; Zhao, Zhongming; Weinstein, John N.; Li, Lei; Ding, Li; Mills, Gordon B.; Laird, Peter W.; Wheeler, David A.; Shmulevich, Ilya; Monnat Junior, Raymond J.; Xiao, Yonghong; Wang, Chen; Noushmehr, Houtan; Carlotti Júnior, Carlos Gilberto; Santos, José Sebastião dos; Kemp, Rafael; Sankarankuty, Ajith Kumar; Tirapelli, Daniela Pretti da Cunha
Source: Cell Reports. Unidade: FMRP
Subjects: GENÔMICA, CARCINOMA, CARCINOMA DE CÉLULAS ESCAMOSAS, PROTEÔMICA, MUTAÇÃO GENÉTICA
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KNIJNENBURG, Theo A. et al. Genomic and molecular landscape of DNA damage repair deficiency across the cancer genome atlas. Cell Reports, v. 23, n. 1, p. 239-254, 2018Tradução . . Disponível em: https://doi.org/10.1016/j.celrep.2018.03.076. Acesso em: 01 nov. 2025.
APA
Knijnenburg, T. A., Wang, L., Zimmermann, M. T., Chambwe, N., Gao, G. F., Cherniack , A. D., et al. (2018). Genomic and molecular landscape of DNA damage repair deficiency across the cancer genome atlas. Cell Reports, 23( 1), 239-254. doi:10.1016/j.celrep.2018.03.076
NLM
Knijnenburg TA, Wang L, Zimmermann MT, Chambwe N, Gao GF, Cherniack AD, Fan H, Shen H, Way GP, Greene CS, Liu Y, Akbani R, Feng B, Donehower LA, Miller C, Shen Y, Karimi M, Chen H, Kim P, Jia P, Shinbrot E, Zhang S, Liu J, Hu H, Bailey MH, Yau C, Wolf DM, Zhao Z, Weinstein JN, Li L, Ding L, Mills GB, Laird PW, Wheeler DA, Shmulevich I, Monnat Junior RJ, Xiao Y, Wang C, Noushmehr H, Carlotti Júnior CG, Santos JS dos, Kemp R, Sankarankuty AK, Tirapelli DP da C. Genomic and molecular landscape of DNA damage repair deficiency across the cancer genome atlas [Internet]. Cell Reports. 2018 ; 23( 1): 239-254.[citado 2025 nov. 01 ] Available from: https://doi.org/10.1016/j.celrep.2018.03.076
Vancouver
Knijnenburg TA, Wang L, Zimmermann MT, Chambwe N, Gao GF, Cherniack AD, Fan H, Shen H, Way GP, Greene CS, Liu Y, Akbani R, Feng B, Donehower LA, Miller C, Shen Y, Karimi M, Chen H, Kim P, Jia P, Shinbrot E, Zhang S, Liu J, Hu H, Bailey MH, Yau C, Wolf DM, Zhao Z, Weinstein JN, Li L, Ding L, Mills GB, Laird PW, Wheeler DA, Shmulevich I, Monnat Junior RJ, Xiao Y, Wang C, Noushmehr H, Carlotti Júnior CG, Santos JS dos, Kemp R, Sankarankuty AK, Tirapelli DP da C. Genomic and molecular landscape of DNA damage repair deficiency across the cancer genome atlas [Internet]. Cell Reports. 2018 ; 23( 1): 239-254.[citado 2025 nov. 01 ] Available from: https://doi.org/10.1016/j.celrep.2018.03.076
Artigo de periodico
Molecular profiling reveals biologically discrete subsets and pathways of progression in diffuse glioma (2016)
Ceccarelli, Michele; Barthel, Floris P.; Malta, Tathiane M.; Sabedot, Thais S.; Salama, Sofie R.; Murray, Bradley A.; Morozova, Olena; Newton, Yulia; Radenbaugh, Amie; Pagnotta, Stefano M.; Anjum, Samreen; Wang, Jiguang; Manyam, Ganiraju; Zoppoli, Pietro; Ling, Shiyun; Rao, Arjun A.; Grifford, Mia; Cherniack, Andrew D.; Zhang, Hailei; Poisson, Laila; Carlotti Júnior, Carlos Gilberto; Tirapelli, Daniela Pretti da Cunha; Rao, Arvind; Mikkelsen, Tom; Lau, Ching C.; Yung, W.K. Alfred; Rabadan, Raul; Huse, Jason; Brat, Daniel J.; Lehman, Norman L.; Barnholtz-Sloan, Jill S.; Zheng, Siyuan; Hess, Kenneth; Rao, Ganesh; Meyerson, Matthew; Beroukhim, Rameen; Cooper, Lee; Akbani, Rehan; Wrensch, Margaret; Haussler, David; Aldape, Kenneth D.; Laird, Peter W.; Gutmann, David H.; Noushmehr, Houtan; Iavarone, Antonio; Verhaak, Roel G.W.
Source: Cell. Unidade: FMRP
Subjects: GLIOMA, NEOPLASIAS CEREBRAIS, PROLIFERAÇÃO CELULAR, METILAÇÃO DE DNA, MUTAÇÃO GENÉTICA
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ABNT
CECCARELLI, Michele et al. Molecular profiling reveals biologically discrete subsets and pathways of progression in diffuse glioma. Cell, v. 164, p. 550-563, 2016Tradução . . Disponível em: https://doi.org/10.1016/j.cell.2015.12.028. Acesso em: 01 nov. 2025.
APA
Ceccarelli, M., Barthel, F. P., Malta, T. M., Sabedot, T. S., Salama, S. R., Murray, B. A., et al. (2016). Molecular profiling reveals biologically discrete subsets and pathways of progression in diffuse glioma. Cell, 164, 550-563. doi:10.1016/j.cell.2015.12.028
NLM
Ceccarelli M, Barthel FP, Malta TM, Sabedot TS, Salama SR, Murray BA, Morozova O, Newton Y, Radenbaugh A, Pagnotta SM, Anjum S, Wang J, Manyam G, Zoppoli P, Ling S, Rao AA, Grifford M, Cherniack AD, Zhang H, Poisson L, Carlotti Júnior CG, Tirapelli DP da C, Rao A, Mikkelsen T, Lau CC, Yung WKA, Rabadan R, Huse J, Brat DJ, Lehman NL, Barnholtz-Sloan JS, Zheng S, Hess K, Rao G, Meyerson M, Beroukhim R, Cooper L, Akbani R, Wrensch M, Haussler D, Aldape KD, Laird PW, Gutmann DH, Noushmehr H, Iavarone A, Verhaak RGW. Molecular profiling reveals biologically discrete subsets and pathways of progression in diffuse glioma [Internet]. Cell. 2016 ; 164 550-563.[citado 2025 nov. 01 ] Available from: https://doi.org/10.1016/j.cell.2015.12.028
Vancouver
Ceccarelli M, Barthel FP, Malta TM, Sabedot TS, Salama SR, Murray BA, Morozova O, Newton Y, Radenbaugh A, Pagnotta SM, Anjum S, Wang J, Manyam G, Zoppoli P, Ling S, Rao AA, Grifford M, Cherniack AD, Zhang H, Poisson L, Carlotti Júnior CG, Tirapelli DP da C, Rao A, Mikkelsen T, Lau CC, Yung WKA, Rabadan R, Huse J, Brat DJ, Lehman NL, Barnholtz-Sloan JS, Zheng S, Hess K, Rao G, Meyerson M, Beroukhim R, Cooper L, Akbani R, Wrensch M, Haussler D, Aldape KD, Laird PW, Gutmann DH, Noushmehr H, Iavarone A, Verhaak RGW. Molecular profiling reveals biologically discrete subsets and pathways of progression in diffuse glioma [Internet]. Cell. 2016 ; 164 550-563.[citado 2025 nov. 01 ] Available from: https://doi.org/10.1016/j.cell.2015.12.028
Artigo de periodico
Comprehensive molecular portraits of invasive lobular breast cancer (2015)
Ciriello, Giovanni; Gatza, Michael L.; Beck, Andrew H.; Wilkerson, Matthew D.; Rhie, Suhn K.; Pastore, Alessandro; Zhang, Hailei; McLellan, Michael; Yau, Christina; Kandoth, Cyriac; Bowlby, Reanne; Shen, Hui; Hayat, Sikander; Fieldhouse, Robert; Lester, Susan C.; Tse, Gary M. K.; Factor, Rachel E.; Collins, Laura C.; Allison, Kimberly H.; Chen, Yunn-Yi; Jensen, Kristin; Johnsons, Nicole B.; Oesterreich, Steffi; Mills, Gordon B.; Cherniack, Andrew D.; Robertson, Gordon; Benz, Christopher; Sander, Chris; Laird, Peter W.; Hoadley, Katherine A.; King, Tari A.; Perou, Charles M.; Tiezzi, Daniel Guimarães
Source: Cell. Unidade: FMRP
Subjects: NEOPLASIAS MAMÁRIAS, MUTAÇÃO GENÉTICA, TERAPÊUTICA, EXPRESSÃO GÊNICA, NEOPLASIAS (CLASSIFICAÇÃO)
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CIRIELLO, Giovanni et al. Comprehensive molecular portraits of invasive lobular breast cancer. Cell, v. 163, n. 2, p. 506-519, 2015Tradução . . Disponível em: https://doi.org/10.1016/j.cell.2015.09.033. Acesso em: 01 nov. 2025.
APA
Ciriello, G., Gatza, M. L., Beck, A. H., Wilkerson, M. D., Rhie, S. K., Pastore, A., et al. (2015). Comprehensive molecular portraits of invasive lobular breast cancer. Cell, 163( 2), 506-519. doi:10.1016/j.cell.2015.09.033
NLM
Ciriello G, Gatza ML, Beck AH, Wilkerson MD, Rhie SK, Pastore A, Zhang H, McLellan M, Yau C, Kandoth C, Bowlby R, Shen H, Hayat S, Fieldhouse R, Lester SC, Tse GMK, Factor RE, Collins LC, Allison KH, Chen Y-Y, Jensen K, Johnsons NB, Oesterreich S, Mills GB, Cherniack AD, Robertson G, Benz C, Sander C, Laird PW, Hoadley KA, King TA, Perou CM, Tiezzi DG. Comprehensive molecular portraits of invasive lobular breast cancer [Internet]. Cell. 2015 ; 163( 2): 506-519.[citado 2025 nov. 01 ] Available from: https://doi.org/10.1016/j.cell.2015.09.033
Vancouver
Ciriello G, Gatza ML, Beck AH, Wilkerson MD, Rhie SK, Pastore A, Zhang H, McLellan M, Yau C, Kandoth C, Bowlby R, Shen H, Hayat S, Fieldhouse R, Lester SC, Tse GMK, Factor RE, Collins LC, Allison KH, Chen Y-Y, Jensen K, Johnsons NB, Oesterreich S, Mills GB, Cherniack AD, Robertson G, Benz C, Sander C, Laird PW, Hoadley KA, King TA, Perou CM, Tiezzi DG. Comprehensive molecular portraits of invasive lobular breast cancer [Internet]. Cell. 2015 ; 163( 2): 506-519.[citado 2025 nov. 01 ] Available from: https://doi.org/10.1016/j.cell.2015.09.033
Trabalho de evento-resumo periodico
A pan-glioma characterization of genomic, epigenomic and transcriptomic activities reveals novel relationships between histological subtypes and molecular signatures (2015)
Barthel, Floris P.; Ceccarelli, Michele; Malta, Tathiane M.; Sabedot, Thais S.; Salama, Sofie R.; Pagnotta, Stefano M.; Murray, Bradley A.; Morozova, Olena; Newton, Yulia; Brat, Daniel J.; Cherniack, Andrew D.; Zhang, Hailei; Poisson, Laila; Cooper, Lee; Rabadan, Raul; Laird, Peter W.; Gutmann, David H.; Noushmehr, Houtan; Lavarone, Antonio; Verhaak, G. W.
Source: Neuro-Oncology. Conference titles: Annual Scientific Meeting of the Society for Neuro-Oncology. Unidade: FMRP
Subjects: MUTAÇÃO GENÉTICA, GLIOMA, GENOMAS, EXPRESSÃO GÊNICA, METILAÇÃO DE DNA
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ABNT
BARTHEL, Floris P. et al. A pan-glioma characterization of genomic, epigenomic and transcriptomic activities reveals novel relationships between histological subtypes and molecular signatures. Neuro-Oncology. Cary: Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo. Disponível em: https://doi.org/10.1093/neuonc/nov215.06. Acesso em: 01 nov. 2025. , 2015
APA
Barthel, F. P., Ceccarelli, M., Malta, T. M., Sabedot, T. S., Salama, S. R., Pagnotta, S. M., et al. (2015). A pan-glioma characterization of genomic, epigenomic and transcriptomic activities reveals novel relationships between histological subtypes and molecular signatures. Neuro-Oncology. Cary: Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo. doi:10.1093/neuonc/nov215.06
NLM
Barthel FP, Ceccarelli M, Malta TM, Sabedot TS, Salama SR, Pagnotta SM, Murray BA, Morozova O, Newton Y, Brat DJ, Cherniack AD, Zhang H, Poisson L, Cooper L, Rabadan R, Laird PW, Gutmann DH, Noushmehr H, Lavarone A, Verhaak GW. A pan-glioma characterization of genomic, epigenomic and transcriptomic activities reveals novel relationships between histological subtypes and molecular signatures [Internet]. Neuro-Oncology. 2015 ; 17[citado 2025 nov. 01 ] Available from: https://doi.org/10.1093/neuonc/nov215.06
Vancouver
Barthel FP, Ceccarelli M, Malta TM, Sabedot TS, Salama SR, Pagnotta SM, Murray BA, Morozova O, Newton Y, Brat DJ, Cherniack AD, Zhang H, Poisson L, Cooper L, Rabadan R, Laird PW, Gutmann DH, Noushmehr H, Lavarone A, Verhaak GW. A pan-glioma characterization of genomic, epigenomic and transcriptomic activities reveals novel relationships between histological subtypes and molecular signatures [Internet]. Neuro-Oncology. 2015 ; 17[citado 2025 nov. 01 ] Available from: https://doi.org/10.1093/neuonc/nov215.06
Artigo de periodico
Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin (2014)
Hoadley , Katherine A.; Yau, Christina; Wolf, Denise M.; Cherniack , Andrew D.; Tamborero, David; Ng, Sam; Leiserson, Max D. M.; Niu, Beifang; McLellan, Michael D.; Uzunangelov, Vladislav; Zhang, Jiashan; Kandoth, Cyriac; Akbani, Rehan; Shen, Hui; Omberg, Larsson; Chu, Andy; Margolin, Adam A.; Veer, Laura J. van’t; Lopez-Bigas, Nuria; Laird, Peter W.; Raphael, Benjamin J.; Ding, Li; Robertson, A. Gordon; Byers, Lauren A.; Mills, Gordon B.; Weinstein, John N.; Waes, Carter Van; Chen, Zhong; Collisson, Eric A.; Benz, Christopher C.; Perou, Charles M.; Stuart, Joshua M.; Noushmehr, Houtan
Source: Cell. Unidade: FMRP
Subjects: NEOPLASIAS, CLUSTERS (ANÁLISE)
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HOADLEY , Katherine A. et al. Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin. Cell, v. 158, n. 4, p. 929–944, 2014Tradução . . Disponível em: https://doi.org/10.1016/j.cell.2014.06.049. Acesso em: 01 nov. 2025.
APA
Hoadley , K. A., Yau, C., Wolf, D. M., Cherniack , A. D., Tamborero, D., Ng, S., et al. (2014). Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin. Cell, 158( 4), 929–944. doi:10.1016/j.cell.2014.06.049
NLM
Hoadley KA, Yau C, Wolf DM, Cherniack AD, Tamborero D, Ng S, Leiserson MDM, Niu B, McLellan MD, Uzunangelov V, Zhang J, Kandoth C, Akbani R, Shen H, Omberg L, Chu A, Margolin AA, Veer LJ van’t, Lopez-Bigas N, Laird PW, Raphael BJ, Ding L, Robertson AG, Byers LA, Mills GB, Weinstein JN, Waes CV, Chen Z, Collisson EA, Benz CC, Perou CM, Stuart JM, Noushmehr H. Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin [Internet]. Cell. 2014 ; 158( 4): 929–944.[citado 2025 nov. 01 ] Available from: https://doi.org/10.1016/j.cell.2014.06.049
Vancouver
Hoadley KA, Yau C, Wolf DM, Cherniack AD, Tamborero D, Ng S, Leiserson MDM, Niu B, McLellan MD, Uzunangelov V, Zhang J, Kandoth C, Akbani R, Shen H, Omberg L, Chu A, Margolin AA, Veer LJ van’t, Lopez-Bigas N, Laird PW, Raphael BJ, Ding L, Robertson AG, Byers LA, Mills GB, Weinstein JN, Waes CV, Chen Z, Collisson EA, Benz CC, Perou CM, Stuart JM, Noushmehr H. Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin [Internet]. Cell. 2014 ; 158( 4): 929–944.[citado 2025 nov. 01 ] Available from: https://doi.org/10.1016/j.cell.2014.06.049

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