Artigo de periodico

Genomic and molecular landscape of DNA damage repair deficiency across the cancer genome atlas (2018)

• Authors:
  • Knijnenburg, Theo A.
  • Wang, Linghua
  • Zimmermann, Michael T.
  • Chambwe, Nyasha
  • Gao, Galen F.
  • Cherniack , Andrew D.
  • Fan, Huihui
  • Shen, Hui
  • Way, Gregory P.
  • Greene, Casey S
  • Liu, Yuexin
  • Akbani, Rehan
  • Feng, Bin
  • Donehower, Lawrence A.
  • Miller, Chase
  • Shen, Yang
  • Karimi, Mostafa
  • Chen, Haoran
  • Kim, Pora
  • Jia, Peilin
  • Shinbrot, Eve
  • Zhang, Shaojun
  • Liu, Jianfang
  • Hu, Hai
  • Bailey, Matthew H.
  • Yau, Christina
  • Wolf, Denise M.
  • Zhao, Zhongming
  • Weinstein, John N.
  • Li, Lei
  • Ding, Li
  • Mills, Gordon B.
  • Laird, Peter W.
  • Wheeler, David A.
  • Shmulevich, Ilya
  • Monnat Junior, Raymond J.
  • Xiao, Yonghong
  • Wang, Chen
  • Noushmehr, Houtan
  • Carlotti Júnior, Carlos Gilberto
  • Santos, José Sebastião dos
  • Kemp, Rafael
  • Sankarankuty, Ajith Kumar
  • Tirapelli, Daniela Pretti da Cunha
• USP affiliated authors: NOUSHMEHR, HOUTAN - FMRP ; CARLOTTI JUNIOR, CARLOS GILBERTO - FMRP ; SANTOS, JOSÉ SEBASTIÃO DOS - FMRP ; KEMP, RAFAEL - FMRP ; SANKARANKUTTY, AJITH KUMAR - FMRP ; TIRAPELLI, DANIELA PRETTI DA CUNHA - FMRP
• Unidade: FMRP
• DOI: 10.1016/j.celrep.2018.03.076
• Subjects: GENÔMICA; CARCINOMA; CARCINOMA DE CÉLULAS ESCAMOSAS; PROTEÔMICA; MUTAÇÃO GENÉTICA
• Keywords: DNA damage repair; Somatic mutations; Somatic copy-number alterations; Epigenetic silencing; DNA damage footprints; Mutational signatures; Integrative statistical analysis; Protein structure analysis
• Agências de fomento:
  • U01 CA217883
  • Financiado pelo GBMF
  • Financiado pelo DOD
  • Financiado pelo Mayo Clinic Center for Individualized Medicine
• Language: Inglês
• Imprenta:
  • Publisher place: Cambridge
  • Date published: 2018
• Source:
  • Título: Cell Reports
  • ISSN: 2211-1247
  • Volume/Número/Paginação/Ano: v. 23, n. 1, p. 239-254, 2018

Informações sobre o DOI: 10.1016/j.celrep.2018.03.076 (Fonte: oaDOI API)
• Este periódico é de acesso aberto
• Este artigo é de acesso aberto
• URL de acesso aberto
• Cor do Acesso Aberto: gold
• Licença: cc-by-nc-nd

---

Download do texto completo

Tipo	Nome	Link
	002938364.pdf	Direct link

How to cite

A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas

• ABNT

  KNIJNENBURG, Theo A. et al. Genomic and molecular landscape of DNA damage repair deficiency across the cancer genome atlas. Cell Reports, v. 23, n. 1, p. 239-254, 2018Tradução . . Disponível em: https://doi.org/10.1016/j.celrep.2018.03.076. Acesso em: 31 dez. 2025.

• APA

  Knijnenburg, T. A., Wang, L., Zimmermann, M. T., Chambwe, N., Gao, G. F., Cherniack , A. D., et al. (2018). Genomic and molecular landscape of DNA damage repair deficiency across the cancer genome atlas. Cell Reports, 23( 1), 239-254. doi:10.1016/j.celrep.2018.03.076

• NLM

  Knijnenburg TA, Wang L, Zimmermann MT, Chambwe N, Gao GF, Cherniack AD, Fan H, Shen H, Way GP, Greene CS, Liu Y, Akbani R, Feng B, Donehower LA, Miller C, Shen Y, Karimi M, Chen H, Kim P, Jia P, Shinbrot E, Zhang S, Liu J, Hu H, Bailey MH, Yau C, Wolf DM, Zhao Z, Weinstein JN, Li L, Ding L, Mills GB, Laird PW, Wheeler DA, Shmulevich I, Monnat Junior RJ, Xiao Y, Wang C, Noushmehr H, Carlotti Júnior CG, Santos JS dos, Kemp R, Sankarankuty AK, Tirapelli DP da C. Genomic and molecular landscape of DNA damage repair deficiency across the cancer genome atlas [Internet]. Cell Reports. 2018 ; 23( 1): 239-254.[citado 2025 dez. 31 ] Available from: https://doi.org/10.1016/j.celrep.2018.03.076

• Vancouver

  Knijnenburg TA, Wang L, Zimmermann MT, Chambwe N, Gao GF, Cherniack AD, Fan H, Shen H, Way GP, Greene CS, Liu Y, Akbani R, Feng B, Donehower LA, Miller C, Shen Y, Karimi M, Chen H, Kim P, Jia P, Shinbrot E, Zhang S, Liu J, Hu H, Bailey MH, Yau C, Wolf DM, Zhao Z, Weinstein JN, Li L, Ding L, Mills GB, Laird PW, Wheeler DA, Shmulevich I, Monnat Junior RJ, Xiao Y, Wang C, Noushmehr H, Carlotti Júnior CG, Santos JS dos, Kemp R, Sankarankuty AK, Tirapelli DP da C. Genomic and molecular landscape of DNA damage repair deficiency across the cancer genome atlas [Internet]. Cell Reports. 2018 ; 23( 1): 239-254.[citado 2025 dez. 31 ] Available from: https://doi.org/10.1016/j.celrep.2018.03.076

Últimas obras dos mesmos autores vinculados com a USP cadastradas na BDPI:

• Molecular characterization and clinical relevance of metabolic expression subtypes in human cancers
• Spatial organization and molecular correlation of tumor-infiltrating lymphocytes using deep learning on pathology images
• Machine learning detects pan-cancer ras pathway activation in the cancer genome atlas
• An integrated TCGA pan-cancer clinical data resource to drive high-quality survival outcome analytics
• Pathogenic germline variants in 10,389 adult cancers
• Comprehensive analysis of alternative splicing across tumors from 8,705 patients
• Scalable open science approach for mutation calling of tumor exomes using multiple genomic pipelines
• Oncogenic signaling pathways in the cancer genome atlas
• Comprehensive molecular characterization of the hippo signaling pathway in cancer
• Somatic mutational landscape of splicing factor genes and their functional consequences across 33 cancer types