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Filtros : "Brömme, Dieter" Limpar

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1 - 10 (10 records)

  • Artigo de periodico

    Green asymmetric synthesis of epoxypeptidomimetics and evaluation as human cathepsin K inhibitors (2020)

    Silva, Taynara L.; Santos, Deborah A. dos; Jesus, Hugo C. R. de; Brömme, Dieter; Fernandes, João B.; Paixão, Marcio W.; Corrêa, Arlene G.; Vieira, Paulo Cezar

    Source: Bioorganic & Medicinal Chemistry. Unidade: FCFRP

    Subjects: GENOMAS, COLÁGENO, OSTEOPOROSE, DOENÇAS ÓSSEAS, DENSIDADE ÓSSEA

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    • ABNT

      SILVA, Taynara L. et al. Green asymmetric synthesis of epoxypeptidomimetics and evaluation as human cathepsin K inhibitors. Bioorganic & Medicinal Chemistry, v. 28, n. 15, p. 1-8, 2020Tradução . . Disponível em: https://doi.org/10.1016/j.bmc.2020.115597. Acesso em: 01 nov. 2025.

    • APA

      Silva, T. L., Santos, D. A. dos, Jesus, H. C. R. de, Brömme, D., Fernandes, J. B., Paixão, M. W., et al. (2020). Green asymmetric synthesis of epoxypeptidomimetics and evaluation as human cathepsin K inhibitors. Bioorganic & Medicinal Chemistry, 28( 15), 1-8. doi:10.1016/j.bmc.2020.115597

    • NLM

      Silva TL, Santos DA dos, Jesus HCR de, Brömme D, Fernandes JB, Paixão MW, Corrêa AG, Vieira PC. Green asymmetric synthesis of epoxypeptidomimetics and evaluation as human cathepsin K inhibitors [Internet]. Bioorganic & Medicinal Chemistry. 2020 ; 28( 15): 1-8.[citado 2025 nov. 01 ] Available from: https://doi.org/10.1016/j.bmc.2020.115597

    • Vancouver

      Silva TL, Santos DA dos, Jesus HCR de, Brömme D, Fernandes JB, Paixão MW, Corrêa AG, Vieira PC. Green asymmetric synthesis of epoxypeptidomimetics and evaluation as human cathepsin K inhibitors [Internet]. Bioorganic & Medicinal Chemistry. 2020 ; 28( 15): 1-8.[citado 2025 nov. 01 ] Available from: https://doi.org/10.1016/j.bmc.2020.115597

  • Artigo de periodico

    A composite docking approach for the identification and characterization of ectosteric inhibitors of cathepsin K (2017)

    Law, Simon; Panwar, Preety; Li, Jody; Aguda, Adeleke H.; Jamroz, Andrew; Guido, Rafael Victorio Carvalho ; Brömme, Dieter

    Source: PLOS One. Unidade: IFSC

    Subjects: ENZIMAS, COLÁGENO, INIBIDORES DE ENZIMAS

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    • ABNT

      LAW, Simon et al. A composite docking approach for the identification and characterization of ectosteric inhibitors of cathepsin K. PLOS One, v. 12, n. 10, p. e0186869-1-e0186869-21, 2017Tradução . . Disponível em: https://doi.org/10.1371/journal.pone.0186869. Acesso em: 01 nov. 2025.

    • APA

      Law, S., Panwar, P., Li, J., Aguda, A. H., Jamroz, A., Guido, R. V. C., & Brömme, D. (2017). A composite docking approach for the identification and characterization of ectosteric inhibitors of cathepsin K. PLOS One, 12( 10), e0186869-1-e0186869-21. doi:10.1371/journal.pone.0186869

    • NLM

      Law S, Panwar P, Li J, Aguda AH, Jamroz A, Guido RVC, Brömme D. A composite docking approach for the identification and characterization of ectosteric inhibitors of cathepsin K [Internet]. PLOS One. 2017 ; 12( 10): e0186869-1-e0186869-21.[citado 2025 nov. 01 ] Available from: https://doi.org/10.1371/journal.pone.0186869

    • Vancouver

      Law S, Panwar P, Li J, Aguda AH, Jamroz A, Guido RVC, Brömme D. A composite docking approach for the identification and characterization of ectosteric inhibitors of cathepsin K [Internet]. PLOS One. 2017 ; 12( 10): e0186869-1-e0186869-21.[citado 2025 nov. 01 ] Available from: https://doi.org/10.1371/journal.pone.0186869

  • Artigo de periodico

    A novel approach to inhibit bone resorption: exosite inhibitors against cathepsin K (2016)

    Panwar, Preety; Soe, Kent; Guido, Rafael Victorio Carvalho ; Bueno, Renata V. C.; Delaisse, Jean-Marie; Brömme, Dieter

    Source: British Journal of Pharmacology. Unidade: IFSC

    Subjects: OSTEOPOROSE (TRATAMENTO), COLÁGENO, OSSO E OSSOS

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    • ABNT

      PANWAR, Preety et al. A novel approach to inhibit bone resorption: exosite inhibitors against cathepsin K. British Journal of Pharmacology, v. 173, n. Ja 2016, p. 396-410, 2016Tradução . . Disponível em: https://doi.org/10.1111/bph.13383. Acesso em: 01 nov. 2025.

    • APA

      Panwar, P., Soe, K., Guido, R. V. C., Bueno, R. V. C., Delaisse, J. -M., & Brömme, D. (2016). A novel approach to inhibit bone resorption: exosite inhibitors against cathepsin K. British Journal of Pharmacology, 173( Ja 2016), 396-410. doi:10.1111/bph.13383

    • NLM

      Panwar P, Soe K, Guido RVC, Bueno RVC, Delaisse J-M, Brömme D. A novel approach to inhibit bone resorption: exosite inhibitors against cathepsin K [Internet]. British Journal of Pharmacology. 2016 ; 173( Ja 2016): 396-410.[citado 2025 nov. 01 ] Available from: https://doi.org/10.1111/bph.13383

    • Vancouver

      Panwar P, Soe K, Guido RVC, Bueno RVC, Delaisse J-M, Brömme D. A novel approach to inhibit bone resorption: exosite inhibitors against cathepsin K [Internet]. British Journal of Pharmacology. 2016 ; 173( Ja 2016): 396-410.[citado 2025 nov. 01 ] Available from: https://doi.org/10.1111/bph.13383

  • Artigo de periodico

    Structural requirements for the collagenase and elastase activity of cathepsin K and its selective inhibition by an exosite inhibitor (2015)

    Sharma, Vidhu; Panwar, Preety; O’Donoghue, Anthony J.; Cui, Haoran; Guido, Rafael Victorio Carvalho ; S. Craik, Charles; Brömme, Dieter

    Source: Biochemical Journal. Unidade: IFSC

    Subjects: PROTEÍNAS (PROPRIEDADES), CRISTALOGRAFIA ESTRUTURAL

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    • ABNT

      SHARMA, Vidhu et al. Structural requirements for the collagenase and elastase activity of cathepsin K and its selective inhibition by an exosite inhibitor. Biochemical Journal, v. 465, p. 163-173, 2015Tradução . . Disponível em: https://doi.org/10.1042/BJ20140809. Acesso em: 01 nov. 2025.

    • APA

      Sharma, V., Panwar, P., O’Donoghue, A. J., Cui, H., Guido, R. V. C., S. Craik, C., & Brömme, D. (2015). Structural requirements for the collagenase and elastase activity of cathepsin K and its selective inhibition by an exosite inhibitor. Biochemical Journal, 465, 163-173. doi:10.1042/BJ20140809

    • NLM

      Sharma V, Panwar P, O’Donoghue AJ, Cui H, Guido RVC, S. Craik C, Brömme D. Structural requirements for the collagenase and elastase activity of cathepsin K and its selective inhibition by an exosite inhibitor [Internet]. Biochemical Journal. 2015 ; 465 163-173.[citado 2025 nov. 01 ] Available from: https://doi.org/10.1042/BJ20140809

    • Vancouver

      Sharma V, Panwar P, O’Donoghue AJ, Cui H, Guido RVC, S. Craik C, Brömme D. Structural requirements for the collagenase and elastase activity of cathepsin K and its selective inhibition by an exosite inhibitor [Internet]. Biochemical Journal. 2015 ; 465 163-173.[citado 2025 nov. 01 ] Available from: https://doi.org/10.1042/BJ20140809

  • Artigo de periodico

    Inhibition of LDL-oxidation and antioxidant properties related to polyphenol content of hydrophilic fractions from seaweed Halimeda Incrassata (Ellis) Lamouroux (2012)

    Costa-Mugica, Ariana; Batista-Gonzalez, Ana Elsa; Mondejar, Diadelis; Soto-López, Yosdel; Brito-Navarro, Victor; Vásquez, Ana Maria; Brömme, Dieter; Zaldívar-Muñoz, Claudina; Vidal-Novoa, Alexis; Silva, Ana Mara de Oliveira e; Mancini-Filho, Jorge

    Source: Brazilian Journal of Pharmaceutical Sciences. Unidade: FCF

    Subjects: ANTIOXIDANTES, LIPOPROTEÍNAS

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    • ABNT

      COSTA-MUGICA, Ariana et al. Inhibition of LDL-oxidation and antioxidant properties related to polyphenol content of hydrophilic fractions from seaweed Halimeda Incrassata (Ellis) Lamouroux. Brazilian Journal of Pharmaceutical Sciences, v. 48, n. 1, p. 31-37, 2012Tradução . . Disponível em: https://doi.org/10.1590/s1984-82502012000100004. Acesso em: 01 nov. 2025.

    • APA

      Costa-Mugica, A., Batista-Gonzalez, A. E., Mondejar, D., Soto-López, Y., Brito-Navarro, V., Vásquez, A. M., et al. (2012). Inhibition of LDL-oxidation and antioxidant properties related to polyphenol content of hydrophilic fractions from seaweed Halimeda Incrassata (Ellis) Lamouroux. Brazilian Journal of Pharmaceutical Sciences, 48( 1), 31-37. doi:10.1590/s1984-82502012000100004

    • NLM

      Costa-Mugica A, Batista-Gonzalez AE, Mondejar D, Soto-López Y, Brito-Navarro V, Vásquez AM, Brömme D, Zaldívar-Muñoz C, Vidal-Novoa A, Silva AM de O e, Mancini-Filho J. Inhibition of LDL-oxidation and antioxidant properties related to polyphenol content of hydrophilic fractions from seaweed Halimeda Incrassata (Ellis) Lamouroux [Internet]. Brazilian Journal of Pharmaceutical Sciences. 2012 ; 48( 1): 31-37.[citado 2025 nov. 01 ] Available from: https://doi.org/10.1590/s1984-82502012000100004

    • Vancouver

      Costa-Mugica A, Batista-Gonzalez AE, Mondejar D, Soto-López Y, Brito-Navarro V, Vásquez AM, Brömme D, Zaldívar-Muñoz C, Vidal-Novoa A, Silva AM de O e, Mancini-Filho J. Inhibition of LDL-oxidation and antioxidant properties related to polyphenol content of hydrophilic fractions from seaweed Halimeda Incrassata (Ellis) Lamouroux [Internet]. Brazilian Journal of Pharmaceutical Sciences. 2012 ; 48( 1): 31-37.[citado 2025 nov. 01 ] Available from: https://doi.org/10.1590/s1984-82502012000100004

  • Artigo de periodico

    Structure-activity relationships of hypervalent organochalcogenanes as inhibitors of cysteine cathepsins 'V' and 'S' (2011)

    Piovan, Leandro; Alves, Márcio Fernando Madureira; Juliano, Luiz; Brömme, Dieter; Cunha, Rodrigo Luiz Oliveira Rodrigues; Andrade, Leandro Helgueira

    Source: Bioorganic & Medicinal Chemistry. Unidade: IQ

    Subjects: TELÚRIO, SELÊNIO, ADJUVANTES IMUNOLÓGICOS

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    • ABNT

      PIOVAN, Leandro et al. Structure-activity relationships of hypervalent organochalcogenanes as inhibitors of cysteine cathepsins 'V' and 'S'. Bioorganic & Medicinal Chemistry, v. 19, n. 6, p. 2009-2014 : + supplementary data ( S1-S5), 2011Tradução . . Disponível em: https://doi.org/10.1016/j.bmc.2011.01.054. Acesso em: 01 nov. 2025.

    • APA

      Piovan, L., Alves, M. F. M., Juliano, L., Brömme, D., Cunha, R. L. O. R., & Andrade, L. H. (2011). Structure-activity relationships of hypervalent organochalcogenanes as inhibitors of cysteine cathepsins 'V' and 'S'. Bioorganic & Medicinal Chemistry, 19( 6), 2009-2014 : + supplementary data ( S1-S5). doi:10.1016/j.bmc.2011.01.054

    • NLM

      Piovan L, Alves MFM, Juliano L, Brömme D, Cunha RLOR, Andrade LH. Structure-activity relationships of hypervalent organochalcogenanes as inhibitors of cysteine cathepsins 'V' and 'S' [Internet]. Bioorganic & Medicinal Chemistry. 2011 ; 19( 6): 2009-2014 : + supplementary data ( S1-S5).[citado 2025 nov. 01 ] Available from: https://doi.org/10.1016/j.bmc.2011.01.054

    • Vancouver

      Piovan L, Alves MFM, Juliano L, Brömme D, Cunha RLOR, Andrade LH. Structure-activity relationships of hypervalent organochalcogenanes as inhibitors of cysteine cathepsins 'V' and 'S' [Internet]. Bioorganic & Medicinal Chemistry. 2011 ; 19( 6): 2009-2014 : + supplementary data ( S1-S5).[citado 2025 nov. 01 ] Available from: https://doi.org/10.1016/j.bmc.2011.01.054

  • Artigo de periodico

    Acridone alkaloids as potent inhibitors of cathepsin V (2011)

    Severino, Richele P.; Guido, Rafael Victorio Carvalho ; Marques, Emerson Finco ; Brömme, Dieter; Silva, M. Fátima G. F.; Fernandes, Joáo B.; Andricopulo, Adriano Defini ; Vieira, Paulo C.

    Source: Bioorganic and Medicinal Chemistry. Unidade: IFSC

    Subjects: INIBIDORES DE ENZIMAS, PRODUTOS NATURAIS, ALCALOIDES

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    • ABNT

      SEVERINO, Richele P. et al. Acridone alkaloids as potent inhibitors of cathepsin V. Bioorganic and Medicinal Chemistry, v. 19, n. 4, p. 1477-1481, 2011Tradução . . Disponível em: https://doi.org/10.1016/j.bmc.2010.12.056. Acesso em: 01 nov. 2025.

    • APA

      Severino, R. P., Guido, R. V. C., Marques, E. F., Brömme, D., Silva, M. F. G. F., Fernandes, J. B., et al. (2011). Acridone alkaloids as potent inhibitors of cathepsin V. Bioorganic and Medicinal Chemistry, 19( 4), 1477-1481. doi:10.1016/j.bmc.2010.12.056

    • NLM

      Severino RP, Guido RVC, Marques EF, Brömme D, Silva MFGF, Fernandes JB, Andricopulo AD, Vieira PC. Acridone alkaloids as potent inhibitors of cathepsin V [Internet]. Bioorganic and Medicinal Chemistry. 2011 ; 19( 4): 1477-1481.[citado 2025 nov. 01 ] Available from: https://doi.org/10.1016/j.bmc.2010.12.056

    • Vancouver

      Severino RP, Guido RVC, Marques EF, Brömme D, Silva MFGF, Fernandes JB, Andricopulo AD, Vieira PC. Acridone alkaloids as potent inhibitors of cathepsin V [Internet]. Bioorganic and Medicinal Chemistry. 2011 ; 19( 4): 1477-1481.[citado 2025 nov. 01 ] Available from: https://doi.org/10.1016/j.bmc.2010.12.056

  • Artigo de periodico

    Chemoenzymatic synthesis of organoselenium(IV) compounds and their evaluation as cysteine protease inhibitors (2010)

    Piovan, Leandro; Alves, Márcio Fernando Madureira; Juliano, Luiz; Brömme, Dieter; Cunha, Rodrigo Luiz Oliveira Rodrigues; Andrade, Leandro Helgueira

    Source: Journal of the Brazilian Chemical Society. Unidade: IQ

    Subjects: SELÊNIO, ESTEREOQUÍMICA

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    • ABNT

      PIOVAN, Leandro et al. Chemoenzymatic synthesis of organoselenium(IV) compounds and their evaluation as cysteine protease inhibitors. Journal of the Brazilian Chemical Society, v. 21, n. 11, p. 2108-2118 : + Supplementary Information ( S1-S26), 2010Tradução . . Disponível em: https://doi.org/10.1590/s0103-50532010001100012. Acesso em: 01 nov. 2025.

    • APA

      Piovan, L., Alves, M. F. M., Juliano, L., Brömme, D., Cunha, R. L. O. R., & Andrade, L. H. (2010). Chemoenzymatic synthesis of organoselenium(IV) compounds and their evaluation as cysteine protease inhibitors. Journal of the Brazilian Chemical Society, 21( 11), 2108-2118 : + Supplementary Information ( S1-S26). doi:10.1590/s0103-50532010001100012

    • NLM

      Piovan L, Alves MFM, Juliano L, Brömme D, Cunha RLOR, Andrade LH. Chemoenzymatic synthesis of organoselenium(IV) compounds and their evaluation as cysteine protease inhibitors [Internet]. Journal of the Brazilian Chemical Society. 2010 ; 21( 11): 2108-2118 : + Supplementary Information ( S1-S26).[citado 2025 nov. 01 ] Available from: https://doi.org/10.1590/s0103-50532010001100012

    • Vancouver

      Piovan L, Alves MFM, Juliano L, Brömme D, Cunha RLOR, Andrade LH. Chemoenzymatic synthesis of organoselenium(IV) compounds and their evaluation as cysteine protease inhibitors [Internet]. Journal of the Brazilian Chemical Society. 2010 ; 21( 11): 2108-2118 : + Supplementary Information ( S1-S26).[citado 2025 nov. 01 ] Available from: https://doi.org/10.1590/s0103-50532010001100012

  • Artigo de periodico

    Irreversible inhibition of human cathepsins B, L, S and K by hypervalent tellurium compounds (2009)

    Cunha, Rodrigo Luiz Oliveira Rodrigues; Gouvêa, Iuri E; Feitosa, Geovana Prado Vaz; Alves, Márcio Fernando Madureira; Brömme, Dieter; Comasseto, João Valdir; Tersariol, Ivarne Luis dos Santos; Juliano, Luiz

    Source: Biological Chemistry. Unidade: IQ

    Subjects: SÍNTESE ORGÂNICA, TELÚRIO

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    • ABNT

      CUNHA, Rodrigo Luiz Oliveira Rodrigues et al. Irreversible inhibition of human cathepsins B, L, S and K by hypervalent tellurium compounds. Biological Chemistry, v. 390, n. 11, p. 1205-1212, 2009Tradução . . Disponível em: https://doi.org/10.1515/bc.2009.125. Acesso em: 01 nov. 2025.

    • APA

      Cunha, R. L. O. R., Gouvêa, I. E., Feitosa, G. P. V., Alves, M. F. M., Brömme, D., Comasseto, J. V., et al. (2009). Irreversible inhibition of human cathepsins B, L, S and K by hypervalent tellurium compounds. Biological Chemistry, 390( 11), 1205-1212. doi:10.1515/bc.2009.125

    • NLM

      Cunha RLOR, Gouvêa IE, Feitosa GPV, Alves MFM, Brömme D, Comasseto JV, Tersariol IL dos S, Juliano L. Irreversible inhibition of human cathepsins B, L, S and K by hypervalent tellurium compounds [Internet]. Biological Chemistry. 2009 ; 390( 11): 1205-1212.[citado 2025 nov. 01 ] Available from: https://doi.org/10.1515/bc.2009.125

    • Vancouver

      Cunha RLOR, Gouvêa IE, Feitosa GPV, Alves MFM, Brömme D, Comasseto JV, Tersariol IL dos S, Juliano L. Irreversible inhibition of human cathepsins B, L, S and K by hypervalent tellurium compounds [Internet]. Biological Chemistry. 2009 ; 390( 11): 1205-1212.[citado 2025 nov. 01 ] Available from: https://doi.org/10.1515/bc.2009.125

  • Trabalho de evento-resumo

    Natural products as inhibitiors of cathepsin V: identification, biological activity and molecular modeling (2007)

    Severino, Richele P.; Guido, Rafael Victorio Carvalho ; Vieira, Paulo Cezar; Fernandes, João Batista; Silva, M. Fátima das G. F da; Andricopulo, Adriano Defini ; Brömme, Dieter

    Source: Book of abstracts. Conference titles: Brazilian Conference on Natural Products - BCNP. Unidade: IFSC

    Subjects: PRODUTOS NATURAIS, INIBIDORES DE ENZIMAS, LIGAÇÕES ESTRUTURAIS

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    • ABNT

      SEVERINO, Richele P. et al. Natural products as inhibitiors of cathepsin V: identification, biological activity and molecular modeling. 2007, Anais.. São Paulo: Sociedade Brasileira de Química - SBQ, 2007. Disponível em: http://dell.nossosite.com.br/bcnp2007/media/pub/abst_book.pdf. Acesso em: 01 nov. 2025.

    • APA

      Severino, R. P., Guido, R. V. C., Vieira, P. C., Fernandes, J. B., Silva, M. F. das G. F. da, Andricopulo, A. D., & Brömme, D. (2007). Natural products as inhibitiors of cathepsin V: identification, biological activity and molecular modeling. In Book of abstracts. São Paulo: Sociedade Brasileira de Química - SBQ. Recuperado de http://dell.nossosite.com.br/bcnp2007/media/pub/abst_book.pdf

    • NLM

      Severino RP, Guido RVC, Vieira PC, Fernandes JB, Silva MF das GF da, Andricopulo AD, Brömme D. Natural products as inhibitiors of cathepsin V: identification, biological activity and molecular modeling [Internet]. Book of abstracts. 2007 ;[citado 2025 nov. 01 ] Available from: http://dell.nossosite.com.br/bcnp2007/media/pub/abst_book.pdf

    • Vancouver

      Severino RP, Guido RVC, Vieira PC, Fernandes JB, Silva MF das GF da, Andricopulo AD, Brömme D. Natural products as inhibitiors of cathepsin V: identification, biological activity and molecular modeling [Internet]. Book of abstracts. 2007 ;[citado 2025 nov. 01 ] Available from: http://dell.nossosite.com.br/bcnp2007/media/pub/abst_book.pdf
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