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  • Source: Purinergic Signalling. Unidade: ICB

    Assunto: PARASITOLOGIA

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      BORGES-PEREIRA, Lucas et al. Plasmodium falciparum GFP-E-NTPDase expression at the intraerythrocytic stages and its inhibition blocks the development of the human malaria parasite. Purinergic Signalling, v. 13, n. 3, p. 267-277, 2017Tradução . . Disponível em: https://doi.org/10.1007/s11302-017-9557-4. Acesso em: 02 nov. 2024.
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      Borges-Pereira, L., Meissner, K. A., Wrenger, C., & Garcia, C. R. da S. (2017). Plasmodium falciparum GFP-E-NTPDase expression at the intraerythrocytic stages and its inhibition blocks the development of the human malaria parasite. Purinergic Signalling, 13( 3), 267-277. doi:10.1007/s11302-017-9557-4
    • NLM

      Borges-Pereira L, Meissner KA, Wrenger C, Garcia CR da S. Plasmodium falciparum GFP-E-NTPDase expression at the intraerythrocytic stages and its inhibition blocks the development of the human malaria parasite [Internet]. Purinergic Signalling. 2017 ; 13( 3): 267-277.[citado 2024 nov. 02 ] Available from: https://doi.org/10.1007/s11302-017-9557-4
    • Vancouver

      Borges-Pereira L, Meissner KA, Wrenger C, Garcia CR da S. Plasmodium falciparum GFP-E-NTPDase expression at the intraerythrocytic stages and its inhibition blocks the development of the human malaria parasite [Internet]. Purinergic Signalling. 2017 ; 13( 3): 267-277.[citado 2024 nov. 02 ] Available from: https://doi.org/10.1007/s11302-017-9557-4
  • Source: BioMed Research International. Unidade: ICB

    Subjects: PARASITOLOGIA, ESTRESSE OXIDATIVO

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      BOSCH, Soraya Soledad et al. Oxidative stress control by apicomplexan parasites. BioMed Research International, v. 2015, p. 1-10, 2015Tradução . . Disponível em: https://doi.org/10.1155/2015/351289. Acesso em: 02 nov. 2024.
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      Bosch, S. S., Kronenberger, T., Meissner, K. A., Zimbres, F. M., Stegehake, D., Izui, N. M., et al. (2015). Oxidative stress control by apicomplexan parasites. BioMed Research International, 2015, 1-10. doi:10.1155/2015/351289
    • NLM

      Bosch SS, Kronenberger T, Meissner KA, Zimbres FM, Stegehake D, Izui NM, Schettert I, Liebau E, Wrenger C. Oxidative stress control by apicomplexan parasites [Internet]. BioMed Research International. 2015 ; 2015 1-10.[citado 2024 nov. 02 ] Available from: https://doi.org/10.1155/2015/351289
    • Vancouver

      Bosch SS, Kronenberger T, Meissner KA, Zimbres FM, Stegehake D, Izui NM, Schettert I, Liebau E, Wrenger C. Oxidative stress control by apicomplexan parasites [Internet]. BioMed Research International. 2015 ; 2015 1-10.[citado 2024 nov. 02 ] Available from: https://doi.org/10.1155/2015/351289
  • Source: Current Medicinal Chemistry. Unidade: ICB

    Assunto: PARASITOLOGIA

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      PEREIRA, C. A. et al. Metabolite transporters in trypanosomatid parasites: promising therapeutic targets but.. how to deal with them?. Current Medicinal Chemistry, v. 21, n. 15, p. 1707-1712, 2014Tradução . . Acesso em: 02 nov. 2024.
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      Pereira, C. A., Mayé, M., Wrenger, C., & Miranda, M. R. (2014). Metabolite transporters in trypanosomatid parasites: promising therapeutic targets but.. how to deal with them? Current Medicinal Chemistry, 21( 15), 1707-1712.
    • NLM

      Pereira CA, Mayé M, Wrenger C, Miranda MR. Metabolite transporters in trypanosomatid parasites: promising therapeutic targets but.. how to deal with them? Current Medicinal Chemistry. 2014 ; 21( 15): 1707-1712.[citado 2024 nov. 02 ]
    • Vancouver

      Pereira CA, Mayé M, Wrenger C, Miranda MR. Metabolite transporters in trypanosomatid parasites: promising therapeutic targets but.. how to deal with them? Current Medicinal Chemistry. 2014 ; 21( 15): 1707-1712.[citado 2024 nov. 02 ]
  • Source: Current Medicinal Chemistry. Unidade: ICB

    Assunto: PARASITOLOGIA

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      SILBER, Ariel Mariano e PEREIRA, Claudio A. e WRENGER, Carsten. Drug discovery for infectious agents causing neglected diseases. Current Medicinal Chemistry. Schiphol: Instituto de Ciências Biomédicas, Universidade de São Paulo. . Acesso em: 02 nov. 2024. , 2014
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      Silber, A. M., Pereira, C. A., & Wrenger, C. (2014). Drug discovery for infectious agents causing neglected diseases. Current Medicinal Chemistry. Schiphol: Instituto de Ciências Biomédicas, Universidade de São Paulo.
    • NLM

      Silber AM, Pereira CA, Wrenger C. Drug discovery for infectious agents causing neglected diseases. Current Medicinal Chemistry. 2014 ; 21( 15): 1667.[citado 2024 nov. 02 ]
    • Vancouver

      Silber AM, Pereira CA, Wrenger C. Drug discovery for infectious agents causing neglected diseases. Current Medicinal Chemistry. 2014 ; 21( 15): 1667.[citado 2024 nov. 02 ]
  • Source: BioMed Research International. Unidade: ICB

    Assunto: PARASITOLOGIA

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      DITGEN, Dana et al. Harnessing the helminth secretome for therapeutic immunomodulators. BioMed Research International, v. 2014, p. 1-14, 2014Tradução . . Disponível em: https://doi.org/10.1155/2014/964350. Acesso em: 02 nov. 2024.
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      Ditgen, D., Anandarajah, E. M., Meissner, K. A., Bratting, N., Wrenger, C., & Liebau, E. (2014). Harnessing the helminth secretome for therapeutic immunomodulators. BioMed Research International, 2014, 1-14. doi:10.1155/2014/964350
    • NLM

      Ditgen D, Anandarajah EM, Meissner KA, Bratting N, Wrenger C, Liebau E. Harnessing the helminth secretome for therapeutic immunomodulators [Internet]. BioMed Research International. 2014 ; 2014 1-14.[citado 2024 nov. 02 ] Available from: https://doi.org/10.1155/2014/964350
    • Vancouver

      Ditgen D, Anandarajah EM, Meissner KA, Bratting N, Wrenger C, Liebau E. Harnessing the helminth secretome for therapeutic immunomodulators [Internet]. BioMed Research International. 2014 ; 2014 1-14.[citado 2024 nov. 02 ] Available from: https://doi.org/10.1155/2014/964350
  • Source: Current Medicinal Chemistry. Unidade: ICB

    Assunto: PARASITOLOGIA

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      DREBES, Julia et al. MRSA infections: from classical treatment to suicide drugs. Current Medicinal Chemistry, v. 21, n. 15, p. 1809-1819, 2014Tradução . . Acesso em: 02 nov. 2024.
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      Drebes, J., Künz, M., Pereira, C. A., Betzel, C., & Wrenger, C. (2014). MRSA infections: from classical treatment to suicide drugs. Current Medicinal Chemistry, 21( 15), 1809-1819.
    • NLM

      Drebes J, Künz M, Pereira CA, Betzel C, Wrenger C. MRSA infections: from classical treatment to suicide drugs. Current Medicinal Chemistry. 2014 ; 21( 15): 1809-1819.[citado 2024 nov. 02 ]
    • Vancouver

      Drebes J, Künz M, Pereira CA, Betzel C, Wrenger C. MRSA infections: from classical treatment to suicide drugs. Current Medicinal Chemistry. 2014 ; 21( 15): 1809-1819.[citado 2024 nov. 02 ]
  • Source: Acta Crystallographica Section F, Structural Biology Communications. Unidade: ICB

    Subjects: PARASITOLOGIA, PLASMODIUM FALCIPARUM

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      KRONENBERGER, Thales et al. Purification, crystallization and preliminary X-ray diffraction analysis of pyridoxal kinase from Plasmodium falciparum (PfPdxK). Acta Crystallographica Section F, Structural Biology Communications, v. 70, p. 1550-1555, 2014Tradução . . Disponível em: https://doi.org/10.1107/S2053230X14019864. Acesso em: 02 nov. 2024.
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      Kronenberger, T., Lunev, S., Wrenger, C., & Groves, M. R. (2014). Purification, crystallization and preliminary X-ray diffraction analysis of pyridoxal kinase from Plasmodium falciparum (PfPdxK). Acta Crystallographica Section F, Structural Biology Communications, 70, 1550-1555. doi:10.1107/S2053230X14019864
    • NLM

      Kronenberger T, Lunev S, Wrenger C, Groves MR. Purification, crystallization and preliminary X-ray diffraction analysis of pyridoxal kinase from Plasmodium falciparum (PfPdxK) [Internet]. Acta Crystallographica Section F, Structural Biology Communications. 2014 ; 70 1550-1555.[citado 2024 nov. 02 ] Available from: https://doi.org/10.1107/S2053230X14019864
    • Vancouver

      Kronenberger T, Lunev S, Wrenger C, Groves MR. Purification, crystallization and preliminary X-ray diffraction analysis of pyridoxal kinase from Plasmodium falciparum (PfPdxK) [Internet]. Acta Crystallographica Section F, Structural Biology Communications. 2014 ; 70 1550-1555.[citado 2024 nov. 02 ] Available from: https://doi.org/10.1107/S2053230X14019864
  • Source: Biomed Research International. Unidade: ICB

    Assunto: PARASITOLOGIA

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      KRONENBERGER, Thales et al. Vitamin B6-dependent enzymes in the human malaria parasite Plasmodium falciparum: a druggable target?. Biomed Research International, v. 2014, p. 1-11, 2014Tradução . . Disponível em: https://doi.org/10.1155/2014/108516. Acesso em: 02 nov. 2024.
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      Kronenberger, T., Lindner, J., Meissner, K. A., Zimbres, F. M., Coronado, M. A., Sauer, F. M., et al. (2014). Vitamin B6-dependent enzymes in the human malaria parasite Plasmodium falciparum: a druggable target? Biomed Research International, 2014, 1-11. doi:10.1155/2014/108516
    • NLM

      Kronenberger T, Lindner J, Meissner KA, Zimbres FM, Coronado MA, Sauer FM, Schettert I, Wrenger C. Vitamin B6-dependent enzymes in the human malaria parasite Plasmodium falciparum: a druggable target? [Internet]. Biomed Research International. 2014 ; 2014 1-11.[citado 2024 nov. 02 ] Available from: https://doi.org/10.1155/2014/108516
    • Vancouver

      Kronenberger T, Lindner J, Meissner KA, Zimbres FM, Coronado MA, Sauer FM, Schettert I, Wrenger C. Vitamin B6-dependent enzymes in the human malaria parasite Plasmodium falciparum: a druggable target? [Internet]. Biomed Research International. 2014 ; 2014 1-11.[citado 2024 nov. 02 ] Available from: https://doi.org/10.1155/2014/108516
  • Source: International Journal of Molecular Sciences. Unidade: ICB

    Assunto: PARASITOLOGIA

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      NDJONKA, Dieudonné et al. Natural products as a source for treating neglected parasitic diseases. International Journal of Molecular Sciences, v. 14, n. 2, p. 3395-3439, 2013Tradução . . Disponível em: https://doi.org/10.3390/ijms14023395. Acesso em: 02 nov. 2024.
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      Ndjonka, D., Rapado, L. N., Silber, A. M., Liebau, E., & Wrenger, C. (2013). Natural products as a source for treating neglected parasitic diseases. International Journal of Molecular Sciences, 14( 2), 3395-3439. doi:10.3390/ijms14023395
    • NLM

      Ndjonka D, Rapado LN, Silber AM, Liebau E, Wrenger C. Natural products as a source for treating neglected parasitic diseases [Internet]. International Journal of Molecular Sciences. 2013 ; 14( 2): 3395-3439.[citado 2024 nov. 02 ] Available from: https://doi.org/10.3390/ijms14023395
    • Vancouver

      Ndjonka D, Rapado LN, Silber AM, Liebau E, Wrenger C. Natural products as a source for treating neglected parasitic diseases [Internet]. International Journal of Molecular Sciences. 2013 ; 14( 2): 3395-3439.[citado 2024 nov. 02 ] Available from: https://doi.org/10.3390/ijms14023395
  • Source: Nature Communications. Unidade: ICB

    Subjects: PARASITOLOGIA, ANTIMALÁRICOS, ANIMAIS PARASITOS, ERITRÓCITOS, PLASMODIUM FALCIPARUM, RNA MENSAGEIRO, CROMATOGRAFIA LÍQUIDA DE ALTA PRESSÃO, EXPRESSÃO GÊNICA, REGULAÇÃO GÊNICA, PROTEÍNAS RECOMBINANTES

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      CHAN, Xie Wah Audrey et al. Chemical and genetic validation of thiamine utilization as an antimalarial drug target. Nature Communications, v. 4, p. 1-11, 2013Tradução . . Disponível em: https://doi.org/10.1038/ncomms3060. Acesso em: 02 nov. 2024.
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      Chan, X. W. A., Wrenger, C., Stahl, K., Bärbel Bergmann,, Winterberg, M., Müller, I. B., & Saliba, K. J. (2013). Chemical and genetic validation of thiamine utilization as an antimalarial drug target. Nature Communications, 4, 1-11. doi:10.1038/ncomms3060
    • NLM

      Chan XWA, Wrenger C, Stahl K, Bärbel Bergmann, Winterberg M, Müller IB, Saliba KJ. Chemical and genetic validation of thiamine utilization as an antimalarial drug target [Internet]. Nature Communications. 2013 ; 4 1-11.[citado 2024 nov. 02 ] Available from: https://doi.org/10.1038/ncomms3060
    • Vancouver

      Chan XWA, Wrenger C, Stahl K, Bärbel Bergmann, Winterberg M, Müller IB, Saliba KJ. Chemical and genetic validation of thiamine utilization as an antimalarial drug target [Internet]. Nature Communications. 2013 ; 4 1-11.[citado 2024 nov. 02 ] Available from: https://doi.org/10.1038/ncomms3060
  • Source: Biochemical Journal. Unidade: ICB

    Subjects: PARASITOLOGIA, MALARIA, PLASMODIUM

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      REEKSTING, Shaun B. et al. Exploring inhibition of Pdx1, a component of the PLP synthase complex of the human malaria parasite Plasmodium falciparum. Biochemical Journal, v. 449, n. Ja 2013, p. 175-1871, 2013Tradução . . Disponível em: http://www.biochemj.org/bj/449/0175/bj4490175.htm. Acesso em: 02 nov. 2024.
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      Reeksting, S. B., Müller, I. B., Burger, P. B., Burgos, E. S., Salmon, L., Louw, A. I., et al. (2013). Exploring inhibition of Pdx1, a component of the PLP synthase complex of the human malaria parasite Plasmodium falciparum. Biochemical Journal, 449( Ja 2013), 175-1871. doi:10.1042/BJ20120925
    • NLM

      Reeksting SB, Müller IB, Burger PB, Burgos ES, Salmon L, Louw AI, Birkholtz L-M, Wrenger C. Exploring inhibition of Pdx1, a component of the PLP synthase complex of the human malaria parasite Plasmodium falciparum [Internet]. Biochemical Journal. 2013 ; 449( Ja 2013): 175-1871.[citado 2024 nov. 02 ] Available from: http://www.biochemj.org/bj/449/0175/bj4490175.htm
    • Vancouver

      Reeksting SB, Müller IB, Burger PB, Burgos ES, Salmon L, Louw AI, Birkholtz L-M, Wrenger C. Exploring inhibition of Pdx1, a component of the PLP synthase complex of the human malaria parasite Plasmodium falciparum [Internet]. Biochemical Journal. 2013 ; 449( Ja 2013): 175-1871.[citado 2024 nov. 02 ] Available from: http://www.biochemj.org/bj/449/0175/bj4490175.htm
  • Source: International Journal of Cell Biology. Unidade: ICB

    Assunto: PARASITOLOGIA

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      LINDNER, Jasmin et al. Trafficked Proteins—Druggable in Plasmodium falciparum?. International Journal of Cell Biology, v. 2013, p. 1-13, 2013Tradução . . Disponível em: https://doi.org/10.1155/2013/435981. Acesso em: 02 nov. 2024.
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      Lindner, J., Meissner, K. A., Schettert, I., & Wrenger, C. (2013). Trafficked Proteins—Druggable in Plasmodium falciparum? International Journal of Cell Biology, 2013, 1-13. doi:10.1155/2013/435981
    • NLM

      Lindner J, Meissner KA, Schettert I, Wrenger C. Trafficked Proteins—Druggable in Plasmodium falciparum? [Internet]. International Journal of Cell Biology. 2013 ; 2013 1-13.[citado 2024 nov. 02 ] Available from: https://doi.org/10.1155/2013/435981
    • Vancouver

      Lindner J, Meissner KA, Schettert I, Wrenger C. Trafficked Proteins—Druggable in Plasmodium falciparum? [Internet]. International Journal of Cell Biology. 2013 ; 2013 1-13.[citado 2024 nov. 02 ] Available from: https://doi.org/10.1155/2013/435981
  • Source: Acta Crystallographica Section D, Biological Crystallography. Unidade: ICB

    Assunto: PARASITOLOGIA

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      BEGUM, Afshan et al. Staphylococcus aureus thiaminase II: oligomerization warrants proteolytic protection against serine proteases. Acta Crystallographica Section D, Biological Crystallography, v. 69, p. 2320-2329, 2013Tradução . . Disponível em: https://doi.org/10.1107/S0907444913021550. Acesso em: 02 nov. 2024.
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      Begum, A., Drebes, J., Kikhney, A., Müller, I. B., Perbandt, M., Svergun, D., et al. (2013). Staphylococcus aureus thiaminase II: oligomerization warrants proteolytic protection against serine proteases. Acta Crystallographica Section D, Biological Crystallography, 69, 2320-2329. doi:10.1107/S0907444913021550
    • NLM

      Begum A, Drebes J, Kikhney A, Müller IB, Perbandt M, Svergun D, Wrenger C, Betzel C. Staphylococcus aureus thiaminase II: oligomerization warrants proteolytic protection against serine proteases [Internet]. Acta Crystallographica Section D, Biological Crystallography. 2013 ; 69 2320-2329.[citado 2024 nov. 02 ] Available from: https://doi.org/10.1107/S0907444913021550
    • Vancouver

      Begum A, Drebes J, Kikhney A, Müller IB, Perbandt M, Svergun D, Wrenger C, Betzel C. Staphylococcus aureus thiaminase II: oligomerization warrants proteolytic protection against serine proteases [Internet]. Acta Crystallographica Section D, Biological Crystallography. 2013 ; 69 2320-2329.[citado 2024 nov. 02 ] Available from: https://doi.org/10.1107/S0907444913021550
  • Source: Future Medicinal Chemistry. Unidade: ICB

    Assunto: PARASITOLOGIA

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      KRONENBERGER, Thales e SCHETTERT, Isolmar e WRENGER, Carsten. Targeting the vitamin biosynthesis pathways for the treatment of malaria. Future Medicinal Chemistry, v. 5, n. 7, p. 769-779, 2013Tradução . . Disponível em: https://doi.org/10.4155/FMC.13.43. Acesso em: 02 nov. 2024.
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      Kronenberger, T., Schettert, I., & Wrenger, C. (2013). Targeting the vitamin biosynthesis pathways for the treatment of malaria. Future Medicinal Chemistry, 5( 7), 769-779. doi:10.4155/FMC.13.43
    • NLM

      Kronenberger T, Schettert I, Wrenger C. Targeting the vitamin biosynthesis pathways for the treatment of malaria [Internet]. Future Medicinal Chemistry. 2013 ; 5( 7): 769-779.[citado 2024 nov. 02 ] Available from: https://doi.org/10.4155/FMC.13.43
    • Vancouver

      Kronenberger T, Schettert I, Wrenger C. Targeting the vitamin biosynthesis pathways for the treatment of malaria [Internet]. Future Medicinal Chemistry. 2013 ; 5( 7): 769-779.[citado 2024 nov. 02 ] Available from: https://doi.org/10.4155/FMC.13.43
  • Source: Acta Crystallographica Section F. Structural Biology and Crystallization Communications. Unidade: ICB

    Assunto: PARASITOLOGIA

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      WRENGER, Carsten et al. Crystallization and preliminary X-ray diffraction of malate dehydrogenase from Plasmodium falciparum. Acta Crystallographica Section F. Structural Biology and Crystallization Communications, v. 68, p. 659-662, 2012Tradução . . Disponível em: https://doi.org/10.1107/S1744309112014571. Acesso em: 02 nov. 2024.
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      Wrenger, C., Müller, I. B., Butzloff, S., Jordanova, R., Lunev, S., & Groves, M. R. (2012). Crystallization and preliminary X-ray diffraction of malate dehydrogenase from Plasmodium falciparum. Acta Crystallographica Section F. Structural Biology and Crystallization Communications, 68, 659-662. doi:10.1107/S1744309112014571
    • NLM

      Wrenger C, Müller IB, Butzloff S, Jordanova R, Lunev S, Groves MR. Crystallization and preliminary X-ray diffraction of malate dehydrogenase from Plasmodium falciparum [Internet]. Acta Crystallographica Section F. Structural Biology and Crystallization Communications. 2012 ; 68 659-662.[citado 2024 nov. 02 ] Available from: https://doi.org/10.1107/S1744309112014571
    • Vancouver

      Wrenger C, Müller IB, Butzloff S, Jordanova R, Lunev S, Groves MR. Crystallization and preliminary X-ray diffraction of malate dehydrogenase from Plasmodium falciparum [Internet]. Acta Crystallographica Section F. Structural Biology and Crystallization Communications. 2012 ; 68 659-662.[citado 2024 nov. 02 ] Available from: https://doi.org/10.1107/S1744309112014571
  • Source: Cytometry Part A. Unidade: ICB

    Assunto: PARASITOLOGIA

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      BUTZLOFF, Sabine et al. Cytometric quantification of singlet oxygen in the human malaria parasite Plasmodium falciparum. Cytometry Part A, v. 81, n. 8, p. 698-703, 2012Tradução . . Disponível em: https://doi.org/10.1002/cyto.a.22081. Acesso em: 02 nov. 2024.
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      Butzloff, S., Groves, M. R., Wrenger, C., & Müller, I. B. (2012). Cytometric quantification of singlet oxygen in the human malaria parasite Plasmodium falciparum. Cytometry Part A, 81( 8), 698-703. doi:10.1002/cyto.a.22081
    • NLM

      Butzloff S, Groves MR, Wrenger C, Müller IB. Cytometric quantification of singlet oxygen in the human malaria parasite Plasmodium falciparum [Internet]. Cytometry Part A. 2012 ; 81( 8): 698-703.[citado 2024 nov. 02 ] Available from: https://doi.org/10.1002/cyto.a.22081
    • Vancouver

      Butzloff S, Groves MR, Wrenger C, Müller IB. Cytometric quantification of singlet oxygen in the human malaria parasite Plasmodium falciparum [Internet]. Cytometry Part A. 2012 ; 81( 8): 698-703.[citado 2024 nov. 02 ] Available from: https://doi.org/10.1002/cyto.a.22081
  • Source: Current Drug Metabolism. Unidade: ICB

    Assunto: PARASITOLOGIA

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      WRENGER, Carsten et al. Aspartate aminotransferase - bridging carbohydrate and energy metabolism in Plasmodium Falciparum. Current Drug Metabolism, v. 13, n. 03, p. 332-336, 2012Tradução . . Disponível em: https://doi.org/10.2174/138920012799320400. Acesso em: 02 nov. 2024.
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      Wrenger, C., Müller, I. B., Silber, A. M., Jordanova, R., Lamzin, V. S., & Groves, M. R. (2012). Aspartate aminotransferase - bridging carbohydrate and energy metabolism in Plasmodium Falciparum. Current Drug Metabolism, 13( 03), 332-336. doi:10.2174/138920012799320400
    • NLM

      Wrenger C, Müller IB, Silber AM, Jordanova R, Lamzin VS, Groves MR. Aspartate aminotransferase - bridging carbohydrate and energy metabolism in Plasmodium Falciparum [Internet]. Current Drug Metabolism. 2012 ; 13( 03): 332-336.[citado 2024 nov. 02 ] Available from: https://doi.org/10.2174/138920012799320400
    • Vancouver

      Wrenger C, Müller IB, Silber AM, Jordanova R, Lamzin VS, Groves MR. Aspartate aminotransferase - bridging carbohydrate and energy metabolism in Plasmodium Falciparum [Internet]. Current Drug Metabolism. 2012 ; 13( 03): 332-336.[citado 2024 nov. 02 ] Available from: https://doi.org/10.2174/138920012799320400

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