Uncoupling protein 2 and signal transducer and activator of transcription 1 are targets of human papillomavirus oncoproteins and may be prognostic markers for cervical cancer development (2025)
- Authors:
- Beldi, Mariana Carmezim

- Colunna, Fabiane Cristina

- Lorenzi, Noely Paula Cristina

- Larco, Jordy Alexander Lasso

- Sichero, Laura

- Lino, Vanesca de Souza

- Mota, Giana
- Villa, Luisa Lina

- Tacla, Maricy

- Kamilos, Marcia Farina
- Genta, Maria Luiza Nogueira Dias

- Boccardo, Enrique

- Baracat, Edmund Chada

- Lepique, Ana Paula

- Beldi, Mariana Carmezim
- USP affiliated authors: LORENZI, NOELY PAULA CRISTINA - HU ; BARACAT, EDMUND CHADA - HU ; PIERULIVO, ENRIQUE MARIO BOCCARDO - ICB ; VILLA, LUISA LINA - FM ; LEPIQUE, ANA PAULA - ICB ; GENTA, MARIA LUIZA NOGUEIRA DIAS - FM ; BELDI, MARIANA CARMEZIN - FM ; COLUNNA, FABIANE CRISTINA - ICB ; LINO, VANESCA DE SOUZA - ICB
- Unidades: HU; ICB; FM
- DOI: 10.3389/fonc.2025.1689058
- Subjects: HPV; INFLAMAÇÃO; ESTRESSE OXIDATIVO; ONCOPROTEÍNAS; TRANSDUÇÃO DE SINAL CELULAR; NEOPLASIAS DO COLO UTERINO
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Source:
- Título: Frontiers in Oncology
- ISSN: 2234-943X
- Volume/Número/Paginação/Ano: v. 15, art. 1689058, p. 1-13, 2025
- Este artigo possui versão em acesso aberto
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- PDF de acesso aberto
- Versão do Documento: Versão publicada (Published version)
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Status: Artigo publicado em periódico de acesso aberto (Gold Open Access) -
ABNT
BELDI, Mariana Carmezim et al. Uncoupling protein 2 and signal transducer and activator of transcription 1 are targets of human papillomavirus oncoproteins and may be prognostic markers for cervical cancer development. Frontiers in Oncology, v. 15, p. 1-13, 2025Tradução . . Disponível em: https://pmc.ncbi.nlm.nih.gov/articles/PMC12683336/pdf/fonc-15-1689058.pdf. Acesso em: 15 mar. 2026. -
APA
Beldi, M. C., Colunna, F. C., Lorenzi, N. P. C., Larco, J. A. L., Sichero, L., Lino, V. de S., et al. (2025). Uncoupling protein 2 and signal transducer and activator of transcription 1 are targets of human papillomavirus oncoproteins and may be prognostic markers for cervical cancer development. Frontiers in Oncology, 15, 1-13. doi:10.3389/fonc.2025.1689058 -
NLM
Beldi MC, Colunna FC, Lorenzi NPC, Larco JAL, Sichero L, Lino V de S, Mota G, Villa LL, Tacla M, Kamilos MF, Genta MLND, Boccardo E, Baracat EC, Lepique AP. Uncoupling protein 2 and signal transducer and activator of transcription 1 are targets of human papillomavirus oncoproteins and may be prognostic markers for cervical cancer development [Internet]. Frontiers in Oncology. 2025 ; 15 1-13.[citado 2026 mar. 15 ] Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC12683336/pdf/fonc-15-1689058.pdf -
Vancouver
Beldi MC, Colunna FC, Lorenzi NPC, Larco JAL, Sichero L, Lino V de S, Mota G, Villa LL, Tacla M, Kamilos MF, Genta MLND, Boccardo E, Baracat EC, Lepique AP. Uncoupling protein 2 and signal transducer and activator of transcription 1 are targets of human papillomavirus oncoproteins and may be prognostic markers for cervical cancer development [Internet]. Frontiers in Oncology. 2025 ; 15 1-13.[citado 2026 mar. 15 ] Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC12683336/pdf/fonc-15-1689058.pdf - HPV-mediated resistance to TNF and TRAIL is characterized by global alterations in apoptosis regulatory factors, dysregulation of death receptors, and induction of ROS/RNS
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- HPV16-associated tumors control myeloid cell homeostasis in lymphoid organs, generating a suppressor environment for T cells
- The role of inflammation in HPV carcinogenesis
- Lactate transporters and vascular factors in HPV-induced squamous cell carcinoma of the uterine cervix
- HPV-transformed cells exhibit altered HMGB1-TLR4/MyD88-SARM1 signaling axis
- HPV16 E6 regulates annexin 1 (ANXA1) protein expression in cervical carcinoma cell lines
- SOD2 immunoexpression predicts lymph node metastasis in penile cancer
- Self-sampling for HPV genotyping: a study of vaginal and urine collection in Brazilian women with high-grade lesions
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