Design, synthesis and antitrypanosomatid activity of 2-nitroimidazole-3,5-disubstituted isoxazole compounds based on benznidazole (2023)
- Authors:
- Carvalho, Diego B.
- Costa, Pedro A. N.
- Portapilla, Gisele B.
- Neves, Amarith R. das
- Shiguemoto, Cristiane Y. K.
- Pelizaro, Bruno I.
- Silva, Fernanda
- Piranda, Eliane M.
- Arruda, Carla C. P.
- Gaspari, Priscyla Daniely Marcato
- Cardoso, Iara A.
- Luccas, Pedro H.
- Nonato, Maria Cristina
- Lopes, Norberto Peporine
- Albuquerque, Sérgio de
- Baroni, Adriano C. M.
- USP affiliated authors: GASPARI, PRISCYLA DANIELY MARCATO - FCFRP ; NONATO, MARIA CRISTINA - FCFRP ; LOPES, NORBERTO PEPORINE - FCFRP ; ALBUQUERQUE, SÉRGIO DE - FCFRP
- Unidade: FCFRP
- DOI: 10.1016/j.ejmech.2023.115451
- Subjects: ANTIPROTOZOÁRIOS; DOENÇA DE CHAGAS; FARMACOTERAPIA; TRYPANOSOMA CRUZI
- Keywords: Bioisosterism; Antichagasic activity; Nitroredutases; In vivo therapeutic effect; Antileishmanial activity
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Publisher place: Issy les Moulineaux
- Date published: 2023
- Source:
- Título: European Journal of Medicinal Chemistry
- ISSN: 0223-5234
- Volume/Número/Paginação/Ano: v. 260, art. 115451, p. 1-25, 2023
- Este periódico é de assinatura
- Este artigo NÃO é de acesso aberto
- Cor do Acesso Aberto: closed
-
ABNT
CARVALHO, Diego B. et al. Design, synthesis and antitrypanosomatid activity of 2-nitroimidazole-3,5-disubstituted isoxazole compounds based on benznidazole. European Journal of Medicinal Chemistry, v. 260, p. 1-25, 2023Tradução . . Disponível em: https://doi.org/10.1016/j.ejmech.2023.115451. Acesso em: 29 dez. 2025. -
APA
Carvalho, D. B., Costa, P. A. N., Portapilla, G. B., Neves, A. R. das, Shiguemoto, C. Y. K., Pelizaro, B. I., et al. (2023). Design, synthesis and antitrypanosomatid activity of 2-nitroimidazole-3,5-disubstituted isoxazole compounds based on benznidazole. European Journal of Medicinal Chemistry, 260, 1-25. doi:10.1016/j.ejmech.2023.115451 -
NLM
Carvalho DB, Costa PAN, Portapilla GB, Neves AR das, Shiguemoto CYK, Pelizaro BI, Silva F, Piranda EM, Arruda CCP, Gaspari PDM, Cardoso IA, Luccas PH, Nonato MC, Lopes NP, Albuquerque S de, Baroni ACM. Design, synthesis and antitrypanosomatid activity of 2-nitroimidazole-3,5-disubstituted isoxazole compounds based on benznidazole [Internet]. European Journal of Medicinal Chemistry. 2023 ; 260 1-25.[citado 2025 dez. 29 ] Available from: https://doi.org/10.1016/j.ejmech.2023.115451 -
Vancouver
Carvalho DB, Costa PAN, Portapilla GB, Neves AR das, Shiguemoto CYK, Pelizaro BI, Silva F, Piranda EM, Arruda CCP, Gaspari PDM, Cardoso IA, Luccas PH, Nonato MC, Lopes NP, Albuquerque S de, Baroni ACM. Design, synthesis and antitrypanosomatid activity of 2-nitroimidazole-3,5-disubstituted isoxazole compounds based on benznidazole [Internet]. European Journal of Medicinal Chemistry. 2023 ; 260 1-25.[citado 2025 dez. 29 ] Available from: https://doi.org/10.1016/j.ejmech.2023.115451 - Avaliação in vitro da atividade leishmanicida de triterpenos ácidos isolados de Miconia pepericarpa (Melastomataceae)
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Informações sobre o DOI: 10.1016/j.ejmech.2023.115451 (Fonte: oaDOI API)
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