A novel 4-aminoquinoline chemotype with multistage antimalarial activity and lack of cross-resistance with PfCRT and PfMDR1 mutants (2024)
- Authors:
- Ferreira, Letícia Tiburcio
- Cassiano, Gustavo Capatti
- Alvarez, Luis Carlos Salazar
- Okombo, John
- Calit, Juliana
- Fontinha, Diana
- Gil-Iturbe, Eva
- Coyle, Rachael
- Andrade, Carolina Horta
- Prudencio, Miguel
- Quick, Matthias
- Cravo, Pedro Vitor Lemos
- Lee, Marcus C. S.
- Fidock, David A.
- Costa, Fabio Trindade Maranhão
- Bargieri, Daniel Youssef
- Ferreira, Letícia Tiburcio
- USP affiliated authors: BARGIERI, DANIEL YOUSSEF - ICB ; PAIM, JULIANA CALIT - ICB
- Unidade: ICB
- DOI: 10.1371/journal.ppat.1012627
- Subjects: PARASITOLOGIA; ANTIMALÁRICOS; ÓLEOS ESSENCIAIS; MALÁRIA; PLASMODIUM FALCIPARUM; PROTOZOA; PROTEÍNAS DA MEMBRANA; MUTAÇÃO GENÉTICA
- Agências de fomento:
- Financiamento pela Fundação Bill e Melinda Gates
- Financiamento pela Fundação para Cooperação Internacional em Pesquisa e Ensino Superior - STINT
- Financiamento pelo Conselho Sueco de Pesquisa - Vetenskapsrådet
- Financiamento pelo Horizonte da União Europeia Programa Europa
- Financiamento pelo Instituto Serrapilheira
- Financiamento pelo Institutos de Saúde – NIH
- Financiamento pelo CNPq
- Financiamento pela Fundação de Amparo à Pesquisa do Estado de Goiás
- Financiamento FAPESP
- Language: Inglês
- Imprenta:
- Publisher place: San Francisco, CA
- Date published: 2024
- Source:
- Título: PLoS Pathogens
- ISSN: 1553-7374
- Volume/Número/Paginação/Ano: v. 20, n. 10, art. e1012627, 25 p., 2024
- Este periódico é de acesso aberto
- Este artigo NÃO é de acesso aberto
-
ABNT
FERREIRA, Letícia Tiburcio et al. A novel 4-aminoquinoline chemotype with multistage antimalarial activity and lack of cross-resistance with PfCRT and PfMDR1 mutants. PLoS Pathogens, v. 20, n. 10, p. 25 , 2024Tradução . . Disponível em: https://doi.org/10.1371/journal.ppat.1012627. Acesso em: 09 fev. 2026. -
APA
Ferreira, L. T., Cassiano, G. C., Alvarez, L. C. S., Okombo, J., Calit, J., Fontinha, D., et al. (2024). A novel 4-aminoquinoline chemotype with multistage antimalarial activity and lack of cross-resistance with PfCRT and PfMDR1 mutants. PLoS Pathogens, 20( 10), 25 . doi:10.1371/journal.ppat.1012627 -
NLM
Ferreira LT, Cassiano GC, Alvarez LCS, Okombo J, Calit J, Fontinha D, Gil-Iturbe E, Coyle R, Andrade CH, Prudencio M, Quick M, Cravo PVL, Lee MCS, Fidock DA, Costa FTM, Bargieri DY. A novel 4-aminoquinoline chemotype with multistage antimalarial activity and lack of cross-resistance with PfCRT and PfMDR1 mutants [Internet]. PLoS Pathogens. 2024 ; 20( 10): 25 .[citado 2026 fev. 09 ] Available from: https://doi.org/10.1371/journal.ppat.1012627 -
Vancouver
Ferreira LT, Cassiano GC, Alvarez LCS, Okombo J, Calit J, Fontinha D, Gil-Iturbe E, Coyle R, Andrade CH, Prudencio M, Quick M, Cravo PVL, Lee MCS, Fidock DA, Costa FTM, Bargieri DY. A novel 4-aminoquinoline chemotype with multistage antimalarial activity and lack of cross-resistance with PfCRT and PfMDR1 mutants [Internet]. PLoS Pathogens. 2024 ; 20( 10): 25 .[citado 2026 fev. 09 ] Available from: https://doi.org/10.1371/journal.ppat.1012627 - Computational chemogenomics drug repositioning strategy enables the discovery of epirubicin as a new repurposed hit for Plasmodium Falciparum and P. vivax
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Informações sobre o DOI: 10.1371/journal.ppat.1012627 (Fonte: oaDOI API)
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