A novel Ruthenium(II) complex with lapachol induces G2/M phase arrest through Aurora-B kinase down-regulation and ROS-mediated apoptosis in human prostate adenocarcinoma cells (2021)
- Authors:
- Autor USP: SANTOS, PATRICK WELLINGTON DA SILVA DOS - FMRP
- Unidade: FMRP
- DOI: 10.3389/fonc.2021.682968
- Subjects: APOPTOSE; ADENOCARCINOMA; PRÓSTATA; NEOPLASIAS DOS GENITAIS MASCULINOS
- Keywords: 3D-cell culture; DNA damage (comet assay); ROS - reactive oxygen species; Apoptosis; Lapachol; Naphtoquinones
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Source:
- Título: Frontiers in Oncology
- ISSN: 2234-943X
- Volume/Número/Paginação/Ano: v. 11, art. 682968, [18] p, 2021
- Este periódico é de acesso aberto
- Este artigo é de acesso aberto
- URL de acesso aberto
- Cor do Acesso Aberto: gold
- Licença: cc-by
-
ABNT
DE GRANDIS, Rone A et al. A novel Ruthenium(II) complex with lapachol induces G2/M phase arrest through Aurora-B kinase down-regulation and ROS-mediated apoptosis in human prostate adenocarcinoma cells. Frontiers in Oncology, v. 11, 2021Tradução . . Disponível em: https://doi.org/10.3389/fonc.2021.682968. Acesso em: 28 dez. 2025. -
APA
De Grandis, R. A., Oliveira, K. M., Guedes, A. P. M., Santos, P. W. da S. dos, Aissa, A. F., Batista, A. A., & Pavan, F. R. (2021). A novel Ruthenium(II) complex with lapachol induces G2/M phase arrest through Aurora-B kinase down-regulation and ROS-mediated apoptosis in human prostate adenocarcinoma cells. Frontiers in Oncology, 11. doi:10.3389/fonc.2021.682968 -
NLM
De Grandis RA, Oliveira KM, Guedes APM, Santos PW da S dos, Aissa AF, Batista AA, Pavan FR. A novel Ruthenium(II) complex with lapachol induces G2/M phase arrest through Aurora-B kinase down-regulation and ROS-mediated apoptosis in human prostate adenocarcinoma cells [Internet]. Frontiers in Oncology. 2021 ; 11[citado 2025 dez. 28 ] Available from: https://doi.org/10.3389/fonc.2021.682968 -
Vancouver
De Grandis RA, Oliveira KM, Guedes APM, Santos PW da S dos, Aissa AF, Batista AA, Pavan FR. A novel Ruthenium(II) complex with lapachol induces G2/M phase arrest through Aurora-B kinase down-regulation and ROS-mediated apoptosis in human prostate adenocarcinoma cells [Internet]. Frontiers in Oncology. 2021 ; 11[citado 2025 dez. 28 ] Available from: https://doi.org/10.3389/fonc.2021.682968 - Influência do sulforafano, um inibidor de histonas desacetilases, sobre a instabilidade genômica e mecanismos epigenéticos em linhagens celulares humanas
- Role of exosomal miRNAs and the tumor microenvironment in drug resistance
- Sulforaphane combined with vitamin D induces cytotoxicity mediated by oxidative stress, DNA damage, autophagy, and JNK/MAPK pathway modulation in human prostate tumor cells
- Diallyl disulfide induces chemosensitization to sorafenib, autophagy, and cell cycle arrest and inhibits invasion in hepatocellular carcinoma
- Epigenetic changes induced in mice liver by methionine-supplemented and methionine-deficient diets
- Novel lawsone-containing ruthenium(II) complexes: synthesis, characterization and anticancer activity on 2D and 3D spheroid models of prostate cancer cells
- p-Synephrine induces transcriptional changes via the cAMP/PKA pathway but not cytotoxicity or mutagenicity in human gastrointestinal cells
- Analysis of the cytotoxic, genotoxic, mutagenic, and pro-oxidant effect of synephrine, a component of thermogenic supplements, in human hepatic cells in vitro
- Effects of sulforaphane on the oxidative response, apoptosis, and the transcriptional profile of human stomach mucosa cells in vitro
- Transcriptome and DNA methylation changes modulated by sulforaphane induce cell cycle arrest, apoptosis, DNA damage, and suppression of proliferation in human liver cancer cells
Informações sobre o DOI: 10.3389/fonc.2021.682968 (Fonte: oaDOI API)
Download do texto completo
| Tipo | Nome | Link | |
|---|---|---|---|
 |
003228734.pdf | Direct link |
How to cite
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
