Transcriptome and DNA methylation changes modulated by sulforaphane induce cell cycle arrest, apoptosis, DNA damage, and suppression of proliferation in human liver cancer cells (2020)
- Authors:
- USP affiliated authors: AISSA, ALEXANDRE FERRO - FCFRP ; ANTUNES, LUSANIA MARIA GREGGI - FCFRP ; RODRIGUES, KATIUSKA TUTTIS - FCFRP ; SANTOS, PATRICK WELLINGTON DA SILVA DOS - FMRP ; MACHADO, ANA RITA THOMAZELA - FCFRP ; RIBEIRO, DIEGO LUÍS - FMRP
- Unidades: FCFRP; FMRP
- DOI: 10.1016/j.fct.2019.111047
- Subjects: APOPTOSE; PROLIFERAÇÃO CELULAR; DANO AO DNA; METILAÇÃO DE DNA; EXPRESSÃO GÊNICA; TRANSDUÇÃO DE SINAL CELULAR
- Keywords: Active compound; Chemoprevention; Epigenetics; Isothiocyanate; Sequencing
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Source:
- Título: Food and Chemical Toxicology
- ISSN: 0278-6915
- Volume/Número/Paginação/Ano: v. 136, art. 111047, 2020
- Este periódico é de assinatura
- Este artigo NÃO é de acesso aberto
- Cor do Acesso Aberto: closed
-
ABNT
SANTOS, Patrick Wellington da Silva et al. Transcriptome and DNA methylation changes modulated by sulforaphane induce cell cycle arrest, apoptosis, DNA damage, and suppression of proliferation in human liver cancer cells. Food and Chemical Toxicology, v. 136, 2020Tradução . . Disponível em: https://doi.org/10.1016/j.fct.2019.111047. Acesso em: 28 dez. 2025. -
APA
Santos, P. W. da S., Machado, A. R. T., De Grandis, R. A., Ribeiro, D. L., Tuttis, K., Morselli, M., et al. (2020). Transcriptome and DNA methylation changes modulated by sulforaphane induce cell cycle arrest, apoptosis, DNA damage, and suppression of proliferation in human liver cancer cells. Food and Chemical Toxicology, 136. doi:10.1016/j.fct.2019.111047 -
NLM
Santos PW da S, Machado ART, De Grandis RA, Ribeiro DL, Tuttis K, Morselli M, Aissa AF, Pellegrini M, Antunes LMG. Transcriptome and DNA methylation changes modulated by sulforaphane induce cell cycle arrest, apoptosis, DNA damage, and suppression of proliferation in human liver cancer cells [Internet]. Food and Chemical Toxicology. 2020 ; 136[citado 2025 dez. 28 ] Available from: https://doi.org/10.1016/j.fct.2019.111047 -
Vancouver
Santos PW da S, Machado ART, De Grandis RA, Ribeiro DL, Tuttis K, Morselli M, Aissa AF, Pellegrini M, Antunes LMG. Transcriptome and DNA methylation changes modulated by sulforaphane induce cell cycle arrest, apoptosis, DNA damage, and suppression of proliferation in human liver cancer cells [Internet]. Food and Chemical Toxicology. 2020 ; 136[citado 2025 dez. 28 ] Available from: https://doi.org/10.1016/j.fct.2019.111047 - Epigenetic changes induced in mice liver by methionine-supplemented and methionine-deficient diets
- Effects of sulforaphane on the oxidative response, apoptosis, and the transcriptional profile of human stomach mucosa cells in vitro
- Diallyl disulfide induces chemosensitization to sorafenib, autophagy, and cell cycle arrest and inhibits invasion in hepatocellular carcinoma
- Caffeic acid and chlorogenic acid cytotoxicity, genotoxicity and impact on global DNA methylation in human leukemic cell lines
- p-Synephrine induces transcriptional changes via the cAMP/PKA pathway but not cytotoxicity or mutagenicity in human gastrointestinal cells
- Analysis of the cytotoxic, genotoxic, mutagenic, and pro-oxidant effect of synephrine, a component of thermogenic supplements, in human hepatic cells in vitro
- Novel lawsone-containing ruthenium(II) complexes: synthesis, characterization and anticancer activity on 2D and 3D spheroid models of prostate cancer cells
- Vitamin D supplementation alters the expression of genes associated with hypertension and did not induce DNA damage in rats
- BjussuLAAO-II induces cytotoxicity and alters DNA methylation of cell-cycle genes in monocultured/co-cultured HepG2 cells
- Comparison of the effects of flavone cirsimarin on the proliferation, migration, and invasion of MCF-7 cells grown in 2D monolayer and 3D multicellular tumor spheroids
Informações sobre o DOI: 10.1016/j.fct.2019.111047 (Fonte: oaDOI API)
Download do texto completo
| Tipo | Nome | Link | |
|---|---|---|---|
| 003032464.pdf |
How to cite
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
