Autophagy and inflammasome activation are associated with poor response to FLT3 inhibitors in patients with FLT3-ITD acute myeloid leukemia (2024)
- Authors:
- USP affiliated authors: TRAINA, FABÍOLA - FMRP ; MACHADO NETO, JOÃO AGOSTINHO - ICB ; MACEDO, BRUNNO GILBERTO SANTOS DE - FMRP ; MELO, MANUELA ALBUQUERQUE DE - FMRP
- Unidades: FMRP; ICB
- DOI: 10.1038/s41598-024-74168-z
- Subjects: FARMACOLOGIA; LEUCEMIA MIELOIDE AGUDA; NEOPLASIAS POR TIPO HISTOLÓGICO; LISOSSOMOS; PROTEÍNAS QUINASES; INIBIDORES DE ENZIMAS; MEDICAMENTO; MUTAÇÃO GENÉTICA
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Source:
- Título: Scientific Reports
- ISSN: 2045-2322
- Volume/Número/Paginação/Ano: v. 14, n. 1, art. 23882, 25 p., 2024
- Status:
- Artigo publicado em periódico de acesso aberto (Gold Open Access)
- Versão do Documento:
- Versão publicada (Published version)
- Acessar versão aberta:
-
ABNT
MACEDO, Brunno Gilberto Santos et al. Autophagy and inflammasome activation are associated with poor response to FLT3 inhibitors in patients with FLT3-ITD acute myeloid leukemia. Scientific Reports, v. 14, n. 1, p. 25 , 2024Tradução . . Disponível em: https://doi.org/10.1038/s41598-024-74168-z. Acesso em: 01 abr. 2026. -
APA
Macedo, B. G. S., Melo, M. A. de, Pereira-Martins, D. A., Traina, F., & Machado Neto, J. A. (2024). Autophagy and inflammasome activation are associated with poor response to FLT3 inhibitors in patients with FLT3-ITD acute myeloid leukemia. Scientific Reports, 14( 1), 25 . doi:10.1038/s41598-024-74168-z -
NLM
Macedo BGS, Melo MA de, Pereira-Martins DA, Traina F, Machado Neto JA. Autophagy and inflammasome activation are associated with poor response to FLT3 inhibitors in patients with FLT3-ITD acute myeloid leukemia [Internet]. Scientific Reports. 2024 ; 14( 1): 25 .[citado 2026 abr. 01 ] Available from: https://doi.org/10.1038/s41598-024-74168-z -
Vancouver
Macedo BGS, Melo MA de, Pereira-Martins DA, Traina F, Machado Neto JA. Autophagy and inflammasome activation are associated with poor response to FLT3 inhibitors in patients with FLT3-ITD acute myeloid leukemia [Internet]. Scientific Reports. 2024 ; 14( 1): 25 .[citado 2026 abr. 01 ] Available from: https://doi.org/10.1038/s41598-024-74168-z - A common ground: an in silico assessment of the sources of intrinsic ex vivo resistance to venetoclax in acute myeloid leukemia
- The NLRP3 inflammasome and its role in acute myeloid leukemia onset and development
- An updated outlook on autophagy mechanism and how it supports acute myeloid leukemia maintenance
- Molecular mechanisms associated with autophagy inhibition to overcome resistance to FLT3 inhibitors
- Autophagy induction constitutes a targetable vulnerability in FLT3-mutant acute Myeloid Leukemia cells treated with FLT3-inhibitors
- De novo AML exhibits greater microenvironment dysregulation compared to AML with myelodysplasia-related changes
- Stathmin 1 expression in plasma cell neoplasms. [Carta]
- Increased levels of cyclin D1 negatively impacts on acute lymphoblastic leukemia overall survival
- DNMT3A is highly expressed in bone marrow cells from acute myeloid leukemia patients
- Effects of RhoA and RhoC upon the sensitivity of prostate cancer cells to glutamine deprivation
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