Evaluation of different solvents and solubility parameters on the morphology and diameter of electrospun pullulan nanofibers for curcumin entrapment (2021)
- Authors:
- Autor USP: SANTOS, AMILTON MARTINS DOS - EEL
- Unidade: EEL
- DOI: 10.1016/j.carbpol.2020.117127
- Assunto: POLÍMEROS (QUÍMICA ORGÂNICA)
- Keywords: Pullulan; Curcumin; Electrospinning; Solvent mixture; Hansen solubility parameter
- Agências de fomento:
- Language: Inglês
- Abstract: In this work, the effect of different solvents and solvent binary mixtures on the morphology of electrospun pullulan (Pull) nanofibers was evaluated. The solution viscosities, interactions between solvent and polymer, as well as, solvent vapor pressure, were correlated to the morphology and diameters of the nanofibers. Water, dimethylformamide (DMF) and dimethyl sulfoxide (DMSO) and Teas graphs that rely on the use of Hildebrand solubility parameters were used to identify the most suitable mixtures of solvents. The best binary mixture of solvents to produce Pull nanofibers without defects and with small diameters (203±32 nm) was DMF/DMSO in the ratio of 70/30 wt.%. Pull nanofibers containing 3 and 5 wt. % of curcumin (Curc) in a mixture of DMF/DMSO (70/30 wt.%) were then obtained, and the entrapment efficiency was evaluated using 1H NMR and a UV-–vis spectrophotometer. The results obtained in this work create a new approach for the production of Pull nanofibers for drug delivery systems.
- Imprenta:
- Source:
- Título: Carbohydrate polymers
- ISSN: 0144-8617
- Volume/Número/Paginação/Ano: v.251, p.1-8, art. n. 117-127, 2021
- Este periódico é de assinatura
- Este artigo é de acesso aberto
- URL de acesso aberto
- Cor do Acesso Aberto: green
- Licença: cc-by-nc-nd
-
ABNT
GUERRINI, Lilia Muller et al. Evaluation of different solvents and solubility parameters on the morphology and diameter of electrospun pullulan nanofibers for curcumin entrapment. Carbohydrate polymers, v. 251, n. art. 117-127, p. 1-8, 2021Tradução . . Disponível em: https://doi.org/10.1016/j.carbpol.2020.117127. Acesso em: 28 abr. 2025. -
APA
Guerrini, L. M., Oliveira, M. P., Stapait, C. C., Maric, M., Santos, A. M. dos, & Demarquette, N. R. (2021). Evaluation of different solvents and solubility parameters on the morphology and diameter of electrospun pullulan nanofibers for curcumin entrapment. Carbohydrate polymers, 251( art. 117-127), 1-8. doi:10.1016/j.carbpol.2020.117127 -
NLM
Guerrini LM, Oliveira MP, Stapait CC, Maric M, Santos AM dos, Demarquette NR. Evaluation of different solvents and solubility parameters on the morphology and diameter of electrospun pullulan nanofibers for curcumin entrapment [Internet]. Carbohydrate polymers. 2021 ;251( art. 117-127): 1-8.[citado 2025 abr. 28 ] Available from: https://doi.org/10.1016/j.carbpol.2020.117127 -
Vancouver
Guerrini LM, Oliveira MP, Stapait CC, Maric M, Santos AM dos, Demarquette NR. Evaluation of different solvents and solubility parameters on the morphology and diameter of electrospun pullulan nanofibers for curcumin entrapment [Internet]. Carbohydrate polymers. 2021 ;251( art. 117-127): 1-8.[citado 2025 abr. 28 ] Available from: https://doi.org/10.1016/j.carbpol.2020.117127 - Adsorption study of a macro-RAFT agent onto SiO2-coated Gd2O3:Eu3+ nanorods Requirements and limitations: rquirements and limitation
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Informações sobre o DOI: 10.1016/j.carbpol.2020.117127 (Fonte: oaDOI API)
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