Photobiomodulation therapy in Burning Mouth Syndrome: a randomized double-blind controlled trial (2021)
- Authors:
- Autor USP: GALLO, CAMILA DE BARROS - FO
- Unidade: FO
- Assunto: SÍNDROME DA ARDÊNCIA BUCAL
- Language: Português
- Abstract: Burning Mouth Syndrome (BMS) is characterized by a burning sensation despite the absence of clinical signs and topical clonazepam is considered the gold-standard therapy. This randomized double-blind controlled trial compared the effect of photobiomodulation therapy (PBM) and topical clonazepam for symptom relief in BMS patients. Fifteen patients were eligible and randomly allocated in the intervention or control group. The intervention group underwent 6 sessions of PBM with infrared low power laser (880nm, 90mW, 6J/cm2), which was simulated in the control group turning down the device and reproducing its signaling sounds. The control group rinsed 5 ml of 0.5mg/ml clonazepam solution 3 times a day for 21 days, simulated in the intervention group by rinsing a solution without clonazepam, to ensure the blindness of the received intervention. All patients were evaluated according the IMMPACT-II recommendations for outcome assessment in pain clinical trials, by a blinded research, at the baseline, end of treatment, 30 and 60 days of follow-up. Both treatments offered a significant symptom relief in BMS patients, according the numerical rating scale, without a significant difference between them. PBM provided an earlier effect, maintained for at least 30 days. And topical clonazepam had a slightly higher long-term effect at the 60 day follow-up at other outcomes measures, such as brief pain inventory and oral related quality of life
- Imprenta:
- Source:
- Título: Brazilian Oral Research
- ISSN: 1807-3107
- Volume/Número/Paginação/Ano: v. 35, supl. 3, p. 75, res. HA014, 2021
- Conference titles: Proceedings of the SBPqO Annual Meeting
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ABNT
MAROTTA, B. M et al. Photobiomodulation therapy in Burning Mouth Syndrome: a randomized double-blind controlled trial. Brazilian Oral Research. São Paulo: SBPqO. . Acesso em: 27 dez. 2025. , 2021 -
APA
Marotta, B. M., Freitas, G. D. H., Hanna, R., & Gallo, C. de B. (2021). Photobiomodulation therapy in Burning Mouth Syndrome: a randomized double-blind controlled trial. Brazilian Oral Research. São Paulo: SBPqO. -
NLM
Marotta BM, Freitas GDH, Hanna R, Gallo C de B. Photobiomodulation therapy in Burning Mouth Syndrome: a randomized double-blind controlled trial. Brazilian Oral Research. 2021 ; 35 75.[citado 2025 dez. 27 ] -
Vancouver
Marotta BM, Freitas GDH, Hanna R, Gallo C de B. Photobiomodulation therapy in Burning Mouth Syndrome: a randomized double-blind controlled trial. Brazilian Oral Research. 2021 ; 35 75.[citado 2025 dez. 27 ] - Photobiomodulation is effective in oral lichen planus: a randomized, controlled, double-blind study
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