Synthesis and matched molecular pair analysis of covalent reversible inhibitors of the cysteine protease CPB (2020)
- Authors:
- USP affiliated authors: MONTANARI, CARLOS ALBERTO - IQSC ; LEITÃO, ANDREI - IQSC ; MATOS, THIAGO KELVIN BRITO - IQSC ; BATISTA, PEDRO HENRIQUE JATAI - IQSC ; ROCHO, FERNANDA DOS REIS - IQSC ; VITA, DANIELA DE - IQSC
- Unidade: IQSC
- DOI: 10.1016/j.bmcl.2020.127439
- Subjects: QUÍMICA ORGÂNICA; MEDICAMENTO; INIBIDORES DE ENZIMAS
- Keywords: Dipeptidyl nitrile derivatives; Enzymatic inhibitors; Additive effect; SAR; Crystallographic structure
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Source:
- Título: Bioorganic & Medicinal Chemistry Letters
- ISSN: 0960-894X
- Volume/Número/Paginação/Ano: v. 30, n. 18, p.127439, September 2020
- Este periódico é de assinatura
- Este artigo NÃO é de acesso aberto
- Cor do Acesso Aberto: closed
-
ABNT
MATOS, Thiago Kelvin Brito et al. Synthesis and matched molecular pair analysis of covalent reversible inhibitors of the cysteine protease CPB. Bioorganic & Medicinal Chemistry Letters, v. 30, n. 18, p. 127439, 2020Tradução . . Disponível em: https://doi.org/10.1016/j.bmcl.2020.127439. Acesso em: 28 dez. 2025. -
APA
Matos, T. K. B., Batista, P. H. J., Rocho, F. dos R., Vita, D. de, Pearce, N., Kellam, B., et al. (2020). Synthesis and matched molecular pair analysis of covalent reversible inhibitors of the cysteine protease CPB. Bioorganic & Medicinal Chemistry Letters, 30( 18), 127439. doi:10.1016/j.bmcl.2020.127439 -
NLM
Matos TKB, Batista PHJ, Rocho F dos R, Vita D de, Pearce N, Kellam B, Montanari CA, Leitão A. Synthesis and matched molecular pair analysis of covalent reversible inhibitors of the cysteine protease CPB [Internet]. Bioorganic & Medicinal Chemistry Letters. 2020 ; 30( 18): 127439.[citado 2025 dez. 28 ] Available from: https://doi.org/10.1016/j.bmcl.2020.127439 -
Vancouver
Matos TKB, Batista PHJ, Rocho F dos R, Vita D de, Pearce N, Kellam B, Montanari CA, Leitão A. Synthesis and matched molecular pair analysis of covalent reversible inhibitors of the cysteine protease CPB [Internet]. Bioorganic & Medicinal Chemistry Letters. 2020 ; 30( 18): 127439.[citado 2025 dez. 28 ] Available from: https://doi.org/10.1016/j.bmcl.2020.127439 - N-Sulfonyl dipeptide nitriles as inhibitors of human cathepsin S: In silico design, synthesis and biochemical characterization
- Assessment of the Cruzain Cysteine Protease Reversible and Irreversible Covalent Inhibition Mechanism
- Synthesis of Covalent Reversible Inhibitors of Cysteine Protease CPB
- Novel selective proline-based peptidomimetics for human cathepsin K inhibition
- Development and validation of an analytical method for the quantification of a dipeptidyl nitrile in the extracellular medium using HPLC-UV
- Apoferritin encapsulation of cysteine protease inhibitors for cathepsin L inhibition in cancer cells
- Putative in silico binding modes of nitrile-based peptoids as cysteine protease inhibitors
- Nitrile-based peptoids as cysteine protease inhibitors
- Planejamento molecular baseado na estrutura do ligante
- Desenvolvimento de fármacos
Informações sobre o DOI: 10.1016/j.bmcl.2020.127439 (Fonte: oaDOI API)
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