The effect of memantine, an antagonist of the NMDA glutamate receptor, in in vitro and in vivo infections by Trypanosoma cruzi (2019)
- Authors:
- USP affiliated authors: PRAL, ELIZABETH MIEKO FURUSHO - ICB ; MARINHO, CLAUDIO ROMERO FARIAS - ICB ; SILBER, ARIEL MARIANO - ICB ; SOUZA, HIGO FERNANDO SANTOS - ICB ; ROCHA, SANDRA CARLA - ICB ; DAMASCENO, FLÁVIA SILVA - ICB ; RAPADO, LUDMILA NAKAMURA - ICB
- Unidade: ICB
- DOI: 10.1371/journal.pntd.0007226
- Subjects: PARASITOLOGIA; TRYPANOSOMA CRUZI; DOENÇA DE CHAGAS
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Publisher place: San Francisco
- Date published: 2019
- Source:
- Título: PLoS Neglected Tropical Diseases
- ISSN: 1935-2735
- Volume/Número/Paginação/Ano: v. 13, n. 9, e0007226, p. 1-13, 2019
- Este periódico é de acesso aberto
- Este artigo é de acesso aberto
- URL de acesso aberto
- Cor do Acesso Aberto: gold
- Licença: cc-by
-
ABNT
SOUZA, Higo Fernando Santos et al. The effect of memantine, an antagonist of the NMDA glutamate receptor, in in vitro and in vivo infections by Trypanosoma cruzi. PLoS Neglected Tropical Diseases, v. 13, n. 9, p. 1-13, 2019Tradução . . Disponível em: https://doi.org/10.1371/journal.pntd.0007226. Acesso em: 30 dez. 2025. -
APA
Souza, H. F. S., Rocha, S. C., Damasceno, F. S., Rapado, L. N., Pral, E. M. F., Marinho, C. R. F., & Silber, A. M. (2019). The effect of memantine, an antagonist of the NMDA glutamate receptor, in in vitro and in vivo infections by Trypanosoma cruzi. PLoS Neglected Tropical Diseases, 13( 9), 1-13. doi:10.1371/journal.pntd.0007226 -
NLM
Souza HFS, Rocha SC, Damasceno FS, Rapado LN, Pral EMF, Marinho CRF, Silber AM. The effect of memantine, an antagonist of the NMDA glutamate receptor, in in vitro and in vivo infections by Trypanosoma cruzi [Internet]. PLoS Neglected Tropical Diseases. 2019 ; 13( 9): 1-13.[citado 2025 dez. 30 ] Available from: https://doi.org/10.1371/journal.pntd.0007226 -
Vancouver
Souza HFS, Rocha SC, Damasceno FS, Rapado LN, Pral EMF, Marinho CRF, Silber AM. The effect of memantine, an antagonist of the NMDA glutamate receptor, in in vitro and in vivo infections by Trypanosoma cruzi [Internet]. PLoS Neglected Tropical Diseases. 2019 ; 13( 9): 1-13.[citado 2025 dez. 30 ] Available from: https://doi.org/10.1371/journal.pntd.0007226 - Diminished prolinemia in chronic chagasic patients: a new clue for disease pathology?
- Memantine, an antagonist of the NMDA glutamate receptor, affects cell proliferation, differentiation and the intracellular cycle and induces apoptosis in Trypanosoma cruzi
- The involvement of glutamate metabolism in the resistance to thermal, nutritional, and oxidative stress in Trypanosoma cruzi
- Evaluation of the anti-Trypanosoma cruzi effects of the antipsychotic drug levomepromazine
- Protein kinases on carbon metabolism: potential targets for alternative chemotherapies against toxoplasmosis
- Glutamine analogues impair cell proliferation, the intracellular cycle and metacyclogenesis in Trypanosoma cruzi
- Branched chain amino acids catabolism as a source of new drug targets in pathogenic protists
- Fatty acid oxidation participates in resistance to nutrient-depleted environments in the insect stages of Trypanosoma cruzi
- Branched-chain amino acids modulate the proteomic profile of Trypanosoma cruzi metacyclogenesis induced by proline
- Trypanosoma cruzi synthesizes proline via a Δ1-pyrroline-5-carboxylate reductase whose activity is fine-tuned by NADPH cytosolic pools
Informações sobre o DOI: 10.1371/journal.pntd.0007226 (Fonte: oaDOI API)
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