Anti-cancer activity of a new dihydropyridine derivative, VdiE-2N, in head and neck squamous cell carcinoma (2018)
- Authors:
- USP affiliated authors: SOUSA, LUCAS OLIVEIRA - FCFRP ; GARCIA, CRISTIANA BERNADELLI - FCFRP ; LOPES, NORBERTO PEPORINE - FCFRP ; CURTI, CARLOS - FCFRP ; LEOPOLDINO, ANDRÉIA MACHADO - FCFRP ; GOTO, RENATA NISHIDA - FCFRP ; SOBRAL, LAYS MARTIN - FCFRP
- Unidade: FCFRP
- DOI: 10.1016/j.ejphar.2017.12.009
- Subjects: ANTINEOPLÁSICOS; APOPTOSE; NEOPLASIAS DE CABEÇA E PESCOÇO; MITOCÔNDRIAS; NEOVASCULARIZAÇÃO PATOLÓGICA
- Keywords: Head and Neck cancer; Mitochondria; Antitumor drug; Dihydropyridine
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Source:
- Título: European Journal of Pharmacology
- ISSN: 0014-2999
- Volume/Número/Paginação/Ano: v. 819, p. 198-206, 2018
- Status:
- Artigo possui versão em acesso aberto em repositório (Green Open Access)
- Versão do Documento:
- Versão submetida (Pré-print)
- Acessar versão aberta:
-
ABNT
GOTO, Renata Nishida et al. Anti-cancer activity of a new dihydropyridine derivative, VdiE-2N, in head and neck squamous cell carcinoma. European Journal of Pharmacology, v. 819, p. 198-206, 2018Tradução . . Disponível em: https://doi.org/10.1016/j.ejphar.2017.12.009. Acesso em: 02 abr. 2026. -
APA
Goto, R. N., Sobral, L. M., Sousa, L. O., Garcia, C. B., Lopes, N. P., Marín-Prida, J., et al. (2018). Anti-cancer activity of a new dihydropyridine derivative, VdiE-2N, in head and neck squamous cell carcinoma. European Journal of Pharmacology, 819, 198-206. doi:10.1016/j.ejphar.2017.12.009 -
NLM
Goto RN, Sobral LM, Sousa LO, Garcia CB, Lopes NP, Marín-Prida J, Ochoa-Rodríguez E, Verdecia-Reyes Y, Pardo-Andreu GL, Curti C, Leopoldino AM. Anti-cancer activity of a new dihydropyridine derivative, VdiE-2N, in head and neck squamous cell carcinoma [Internet]. European Journal of Pharmacology. 2018 ; 819 198-206.[citado 2026 abr. 02 ] Available from: https://doi.org/10.1016/j.ejphar.2017.12.009 -
Vancouver
Goto RN, Sobral LM, Sousa LO, Garcia CB, Lopes NP, Marín-Prida J, Ochoa-Rodríguez E, Verdecia-Reyes Y, Pardo-Andreu GL, Curti C, Leopoldino AM. Anti-cancer activity of a new dihydropyridine derivative, VdiE-2N, in head and neck squamous cell carcinoma [Internet]. European Journal of Pharmacology. 2018 ; 819 198-206.[citado 2026 abr. 02 ] Available from: https://doi.org/10.1016/j.ejphar.2017.12.009 - Set/I2PPA2 plays relevant function in oral tumorigenesis by transcription and signaling regulation
- Accumulated SET protein up-regulates and interacts with hnRNPK, increasing its binding to nucleic acids, the Bcl-xS repression, and cellular proliferation
- SET overexpression in HEK293 cells regulates mitochondrial uncoupling proteins levels within a mitochondrial fission/reduced autophagic flux scenario
- SET oncoprotein accumulation regulates transcription through DNA demethylation and histone hypoacetylation
- Autoantibodies against set protein as a potential serum marker in cervical, breast and head and neck cancer patients: detection by ELISA assay
- New insights into heterogenous ribonucleoprotein K expression and accumulation in oral squamous cell carcinoma
- SET protein modulates H4 histone methylation status and regulates miR-137 level in oral squamous cell carcinoma
- Proteomic approaches identify members of cofilin pathway involved in oral tumorigenesis
- Different responses of two HNSCC cell lineages to oxidative stress
- Knockdown of SET protein sensitizes HNSCC-HN12 cells to UCN-01
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