Molecular design, synthesis and trypanocidal activity of dipeptidyl nitriles as cruzain inhibitors (2015)
- Authors:
- USP affiliated authors: ALBUQUERQUE, SÉRGIO DE - FCFRP ; LEITÃO, ANDREI - IQSC ; MONTANARI, CARLOS ALBERTO - IQSC
- Unidades: FCFRP; IQSC
- DOI: 10.1371/journal.pntd.0003916
- Assunto: QUÍMICA MÉDICA
- Language: Inglês
- Source:
- Título: PLOS Neglected Tropical Diseases
- ISSN: 1935-2735
- Volume/Número/Paginação/Ano: v. 9, n. 7, 24 p., 2015
- Este periódico é de acesso aberto
- Este artigo é de acesso aberto
- URL de acesso aberto
- Cor do Acesso Aberto: gold
- Licença: cc-by
-
ABNT
AVELAR, Leandro Antonio Alves et al. Molecular design, synthesis and trypanocidal activity of dipeptidyl nitriles as cruzain inhibitors. PLOS Neglected Tropical Diseases, v. 9, n. 7, p. 24 , 2015Tradução . . Disponível em: https://doi.org/10.1371/journal.pntd.0003916. Acesso em: 26 dez. 2025. -
APA
Avelar, L. A. A., Camilo, C. D., Albuquerque, S. de, Fernandes, W. B., Gonçalez, C., Kenny, P. W., et al. (2015). Molecular design, synthesis and trypanocidal activity of dipeptidyl nitriles as cruzain inhibitors. PLOS Neglected Tropical Diseases, 9( 7), 24 . doi:10.1371/journal.pntd.0003916 -
NLM
Avelar LAA, Camilo CD, Albuquerque S de, Fernandes WB, Gonçalez C, Kenny PW, Leitão A, McKerrow JH, Montanari CA, Orozco EVM, Ribeiro JFR, Rocha JR, Rosini F, Saidel MÉ. Molecular design, synthesis and trypanocidal activity of dipeptidyl nitriles as cruzain inhibitors [Internet]. PLOS Neglected Tropical Diseases. 2015 ; 9( 7): 24 .[citado 2025 dez. 26 ] Available from: https://doi.org/10.1371/journal.pntd.0003916 -
Vancouver
Avelar LAA, Camilo CD, Albuquerque S de, Fernandes WB, Gonçalez C, Kenny PW, Leitão A, McKerrow JH, Montanari CA, Orozco EVM, Ribeiro JFR, Rocha JR, Rosini F, Saidel MÉ. Molecular design, synthesis and trypanocidal activity of dipeptidyl nitriles as cruzain inhibitors [Internet]. PLOS Neglected Tropical Diseases. 2015 ; 9( 7): 24 .[citado 2025 dez. 26 ] Available from: https://doi.org/10.1371/journal.pntd.0003916 - Dipeptidyl nitrile derivatives have cytostatic effects against Leishmania spp. promastigotes
- Anti-trypanosomal activity of non-peptidic nitrile-based cysteine protease inhibitors
- Discovery of 2-aminopyridine Derivatives with Antichagasic and Antileishmanial Activity Using Phenotypic Assays
- Planejamento molecular baseado na estrutura do ligante
- Desenvolvimento de fármacos
- Proteolytic activity inhibition inside the living cells from leishmania species by Dipeptidyl nitriles derivates
- Targeting the Shc-EGFR interaction with indomethacin inhibits MAP kinase pathway signalling
- In silico selection and cell-based characterization of selective and bioactive compounds for androgen-dependent prostate cancer cell
- On the study of halogen bond interaction to increase cruzain affinity of covalently boundd reversible inhibitors
- Ligand efficiency metrics considered harmful
Informações sobre o DOI: 10.1371/journal.pntd.0003916 (Fonte: oaDOI API)
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