Dentin-induced in vivo inflammatory response and in vitro activation of murine macrophages (2003)
- Authors:
- USP affiliated authors: LARA, VANESSA SOARES - FOB ; CUNHA, FERNANDO DE QUEIROZ - FMRP
- Unidades: FOB; FMRP
- Subjects: ÓXIDO NÍTRICO; CÉLULAS; RAIZ DENTÁRIA
- Language: Inglês
- Abstract: The activation of inflammatory cells and consequent release of mediators play an important role in the resorption of mineralized tissues. In the present study, we examined the ability of dentin extracts to induce inflammatory cell recruitment and activation. We showed here that dentin extracts triggered an intense cell migration and progressive cell maturation, in a time and dose dependent manner. Expression of interleukin-1 'beta' (IL-1'beta'), tumor necrosis factor-'alfa' (TNF-'alfa'), nitric oxide (NO), and hydrogen peroxide ('H IND.2''O IND.2') was also up-regulated by dentin extracts. These results show that inflammatory events can be elicited in response to dentin, which may suggest a possible involvement of dentin molecules in the inflammatory events, coupled with their release at the root resorption sites
- Imprenta:
- Source:
- Título: Journal of dental research
- ISSN: 0022-0345
- Volume/Número/Paginação/Ano: v. 82, n. 6, p. 460-465, 2003
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ABNT
LARA, Vanessa Soares et al. Dentin-induced in vivo inflammatory response and in vitro activation of murine macrophages. Journal of dental research, v. 82, n. 6, p. 460-465, 2003Tradução . . Acesso em: 13 fev. 2026. -
APA
Lara, V. S., Figueiredo, F., Silva, T. A. da, & Cunha, F. de Q. (2003). Dentin-induced in vivo inflammatory response and in vitro activation of murine macrophages. Journal of dental research, 82( 6), 460-465. -
NLM
Lara VS, Figueiredo F, Silva TA da, Cunha F de Q. Dentin-induced in vivo inflammatory response and in vitro activation of murine macrophages. Journal of dental research. 2003 ; 82( 6): 460-465.[citado 2026 fev. 13 ] -
Vancouver
Lara VS, Figueiredo F, Silva TA da, Cunha F de Q. Dentin-induced in vivo inflammatory response and in vitro activation of murine macrophages. Journal of dental research. 2003 ; 82( 6): 460-465.[citado 2026 fev. 13 ] - Mast cells produce nitric oxide along with phagocytosis of C. albicans
- Mast cells phagocyte Candida albicans and produce nitric oxide by mechanisms involving TLR2 and Dectin-1
- Differential expression of chemokines and chemokine receptors in inflammatory periapical diseases
- Dentin sialoprotein and phosphoprotein induce neutrophil recruitment a mechanism dependent on IL-1(beta), TNF-(alfa), and CXC chemokines
- Morphologic evaluation and expression of matrix metalloproteinases-2 and 9 and nitric oxide during experimental periodontal disease in rat
- Macrophages and mast cells control the neutrophil migration induced by dentin proteins
- Cytokine and chemokine response of bone cells after dentin challenge in vitro
- Equisetum Giganteum extract and denture stomatitis: study of anti-adherent action against Candida Albicans
- Unicystic ameloblastoma with diverse histological variants and hyaline ring granulomas
- Antimicrobial activity of Equisetum Giganteum extract against clinical strains of Candida Albicans, Escherichia Coli, and standard strain of Staphylococcus aureus
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