Effects of treadmill running on sensorial and motor behaviour of spinal cord contused rats (2002)
- Authors:
- Autor USP: CHADI, GERSON - ICB
- Unidade: ICB
- Assunto: ANATOMIA
- Language: Inglês
- Abstract: Objective: Physical activity exerts effects on central nervous system (CNS) since exercise triggers expression of neurotrophic molecules and stimulates CNS plasticity. Furthermore, it is possible that potential protective effects promoted by physical activity on lesioned CNS depend on the injury type. Methods and Results: Adult rats, trained on a treadmill for 4 weeks, and sedentary rats were submitted to a moderate spinal cord injury by dropping a 10g rod (25mm distance) using the NYU Impactor. A group of sedentary rats were submitted to a sham operation. Rats received methypredinisolone just after the contusion and 2 hours later. Trained group has continued running on treadmill after spinal cord lesion for 4 weeks. The motor behavior was evaluated by BBB score and by a computerized infrared motion sensor activity monitor. Decreased BBB scores were found in lesioned rats at the time-points, however a spontaneous recovery occurred post surgery. BBB score was smaller in the sedentary group compared to trained rats by 7 days post lesion, however no further differences were found between lesioned groups after 7 days. The infrared monitor also showed significant differences between lesioned sedentary and trained rats only at 7 days post spinal cord lesion. Conclusion: Physical activity may be important for functional recovery after a spinal cord contuse injury
- Imprenta:
- Publisher: Comissão de Cultura e Extensão Universitária do ICB/USP
- Publisher place: São Paulo
- Date published: 2002
- Source:
- Título: Resumos
- Conference titles: Congresso Instituto Ciências Biomédicas, IV
-
ABNT
ANDRADE, M S R e LEME, R J A e CHADI, G. Effects of treadmill running on sensorial and motor behaviour of spinal cord contused rats. 2002, Anais.. São Paulo: Comissão de Cultura e Extensão Universitária do ICB/USP, 2002. . Acesso em: 13 jan. 2026. -
APA
Andrade, M. S. R., Leme, R. J. A., & Chadi, G. (2002). Effects of treadmill running on sensorial and motor behaviour of spinal cord contused rats. In Resumos. São Paulo: Comissão de Cultura e Extensão Universitária do ICB/USP. -
NLM
Andrade MSR, Leme RJA, Chadi G. Effects of treadmill running on sensorial and motor behaviour of spinal cord contused rats. Resumos. 2002 ;[citado 2026 jan. 13 ] -
Vancouver
Andrade MSR, Leme RJA, Chadi G. Effects of treadmill running on sensorial and motor behaviour of spinal cord contused rats. Resumos. 2002 ;[citado 2026 jan. 13 ] - On the presence of the bfgf immunoreactivity in the spinal cord and dorsal root ganglia of the adult rat
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