@article{article445678b1, title = {Reconstructed ancestral enzymes reveal that negative selection drove the evolution of substrate specificity in ADP-dependent kinases}, author = {Castro-Fernandez, Víctor and Herrera-Morande, Alejandra and Zamora, Ricardo and Merino, Felipe and Gonzalez-Ordenes, Felipe and Padilla-Salinas, Felipe and Pereira, Humberto d'Muniz and Brandão-Neto, José and Garratt, Richard Charles and Guixe, Victoria}, year = {2017}, doi = {10.1074/jbc.M117.790865}, journal = {Journal of Biological Chemistry} }