Common genetic causes of holoprosencephaly are limited to a small set of evolutionarily conserved driver genes of midline development coordinated by TGF-β, hedgehog, and FGF signaling - Roessler, Erich; Hu, Ping; Marino, Juliana; Hong, Sungkook; Hart, Rachel; Berger, Seth; Martinez, Ariel; Abe, Yu; Kruszka, Paul; Thomas, James W; Mullikin, James C; NISC Comparative Sequencing Program; et al. (Human Mutation, 2018)