Resistance to ambruticin in mediated by a remodeling of the fungal cell wall and the exposure to this drug in an ex vivo skin model leads to the inhibition of the expression of subtilisin protease 5 gene in the dermatophyte Trichophyton rubrum - Peres, N. T. A.; Gras, D. E.; Martins, M. D.; Rossi Filho, Antonio; Prade, R. A.; Martinez-Rossi, Nilce Maria (Reunião de Genética de Microrganismos (REGEM), 2010)