@inbook{inbookf2ed49bb, title = {Lead optimization in drug discovery}, author = {Barcelos, Mariana Pegrucci and Gomes, Suzane Quintana and Federico, Leonardo Bruno and Francischini, Isaque Antônio Galindo and Melim, Lorane Izabel da Silva Hage and Silva, Guilherme Martins da and Silva, Carlos Henrique Tomich de Paula da}, year = {2022}, doi = {10.1007/978-3-031-07622-0_19}, publisher = {Springer}, journal = {Research topics in bioactivity, environment and energy: experimental and theoretical tools} }