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Artigo de periodico
Indole-2-carboxamides optimization for antiplasmodial activity (2025)
Kumar, Malkeet; Ahmad, Anees ; Aguiar, Anna Caroline Campos ; Maluf, Sarah El Chamy ; Shamim, Anwar ; Ferrer, Mariana Casal ; Souza, Guilherme Eduardo de ; Gazarini, Marcos Leoni ; Pereira, Dhelio Batista ; Geldern, Thomas W. von ; Baud, Delphine ; Jones, Barry; Mondal, Susanta Kumar; Willis, Paul A. ; Guido, Rafael Victorio Carvalho ; Dias, Luiz Carlos
Source: ACS Bio and Med Chem Au. Unidade: IFSC
Subjects: MALÁRIA, PLANEJAMENTO DE FÁRMACOS, RESISTÊNCIA MICROBIANA ÀS DROGAS, EXPRESSÃO GÊNICA
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ABNT
KUMAR, Malkeet et al. Indole-2-carboxamides optimization for antiplasmodial activity. ACS Bio and Med Chem Au, v. 5, n. 5, p. 821-839 + supporting information, 2025Tradução . . Disponível em: https://doi.org/10.1021/acsbiomedchemau.5c00058. Acesso em: 08 nov. 2025.
APA
Kumar, M., Ahmad, A., Aguiar, A. C. C., Maluf, S. E. C., Shamim, A., Ferrer, M. C., et al. (2025). Indole-2-carboxamides optimization for antiplasmodial activity. ACS Bio and Med Chem Au, 5( 5), 821-839 + supporting information. doi:10.1021/acsbiomedchemau.5c00058
NLM
Kumar M, Ahmad A, Aguiar ACC, Maluf SEC, Shamim A, Ferrer MC, Souza GE de, Gazarini ML, Pereira DB, Geldern TW von, Baud D, Jones B, Mondal SK, Willis PA, Guido RVC, Dias LC. Indole-2-carboxamides optimization for antiplasmodial activity [Internet]. ACS Bio and Med Chem Au. 2025 ; 5( 5): 821-839 + supporting information.[citado 2025 nov. 08 ] Available from: https://doi.org/10.1021/acsbiomedchemau.5c00058
Vancouver
Kumar M, Ahmad A, Aguiar ACC, Maluf SEC, Shamim A, Ferrer MC, Souza GE de, Gazarini ML, Pereira DB, Geldern TW von, Baud D, Jones B, Mondal SK, Willis PA, Guido RVC, Dias LC. Indole-2-carboxamides optimization for antiplasmodial activity [Internet]. ACS Bio and Med Chem Au. 2025 ; 5( 5): 821-839 + supporting information.[citado 2025 nov. 08 ] Available from: https://doi.org/10.1021/acsbiomedchemau.5c00058
Artigo de periodico
A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo (2024)
Xie, Stanley C. ; Guido, Rafael Victorio Carvalho
Source: PLOS Pathogens. Unidade: IFSC
Subjects: PLASMODIUM FALCIPARUM, ANTIMALÁRICOS, FÁRMACOS
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XIE, Stanley C. e GUIDO, Rafael Victorio Carvalho. A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo. PLOS Pathogens, v. 20, n. 12, p. e1012429-1-e1012429-28 + supporting information, 2024Tradução . . Disponível em: https://doi.org/10.1371/journal.ppat.1012429. Acesso em: 08 nov. 2025.
APA
Xie, S. C., & Guido, R. V. C. (2024). A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo. PLOS Pathogens, 20( 12), e1012429-1-e1012429-28 + supporting information. doi:10.1371/journal.ppat.1012429
NLM
Xie SC, Guido RVC. A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo [Internet]. PLOS Pathogens. 2024 ; 20( 12): e1012429-1-e1012429-28 + supporting information.[citado 2025 nov. 08 ] Available from: https://doi.org/10.1371/journal.ppat.1012429
Vancouver
Xie SC, Guido RVC. A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo [Internet]. PLOS Pathogens. 2024 ; 20( 12): e1012429-1-e1012429-28 + supporting information.[citado 2025 nov. 08 ] Available from: https://doi.org/10.1371/journal.ppat.1012429
Trabalho de evento-resumo
Isolation, identification, in vitro and in vivo anti-plasmodial activity of guanidine alkaloids from Monanchora aff. arbuscula (2023)
Noronha, Anderson Lombardo; Borges, Natália Menezes Moreira; Mendes, Giovana Rossi ; Amorim, Marcelo Rodrigues de ; Guido, Rafael Victorio Carvalho ; Hajdu, Eduardo Carlos Meduna; Ferreira, Antônio Gilberto ; Berlinck, Roberto Gomes de Souza
Source: Anais eletrônicos. Conference titles: Brazilian Conference on Natural Products - BNCP. Unidades: IFSC, IQSC
Subjects: PLANEJAMENTO DE FÁRMACOS, ANTIMALÁRICOS, PLASMODIUM FALCIPARUM
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ABNT
NORONHA, Anderson Lombardo et al. Isolation, identification, in vitro and in vivo anti-plasmodial activity of guanidine alkaloids from Monanchora aff. arbuscula. 2023, Anais.. Campinas: Galoá, 2023. Disponível em: https://proceedings.science/bcnp-series/bcnp-2023/papers/isolation-identification-in-vitro-and-in-vivo-anti-plasmodial-activity-of-guanid?lang=en#. Acesso em: 08 nov. 2025.
APA
Noronha, A. L., Borges, N. M. M., Mendes, G. R., Amorim, M. R. de, Guido, R. V. C., Hajdu, E. C. M., et al. (2023). Isolation, identification, in vitro and in vivo anti-plasmodial activity of guanidine alkaloids from Monanchora aff. arbuscula. In Anais eletrônicos. Campinas: Galoá. Recuperado de https://proceedings.science/bcnp-series/bcnp-2023/papers/isolation-identification-in-vitro-and-in-vivo-anti-plasmodial-activity-of-guanid?lang=en#
NLM
Noronha AL, Borges NMM, Mendes GR, Amorim MR de, Guido RVC, Hajdu ECM, Ferreira AG, Berlinck RG de S. Isolation, identification, in vitro and in vivo anti-plasmodial activity of guanidine alkaloids from Monanchora aff. arbuscula [Internet]. Anais eletrônicos. 2023 ;[citado 2025 nov. 08 ] Available from: https://proceedings.science/bcnp-series/bcnp-2023/papers/isolation-identification-in-vitro-and-in-vivo-anti-plasmodial-activity-of-guanid?lang=en#
Vancouver
Noronha AL, Borges NMM, Mendes GR, Amorim MR de, Guido RVC, Hajdu ECM, Ferreira AG, Berlinck RG de S. Isolation, identification, in vitro and in vivo anti-plasmodial activity of guanidine alkaloids from Monanchora aff. arbuscula [Internet]. Anais eletrônicos. 2023 ;[citado 2025 nov. 08 ] Available from: https://proceedings.science/bcnp-series/bcnp-2023/papers/isolation-identification-in-vitro-and-in-vivo-anti-plasmodial-activity-of-guanid?lang=en#
Artigo de periodico
Optimization of Plasmodium vivax infection of colonized Amazonian Anopheles darlingi (2023)
Andrade, Alice Oliveira; Santos, Najara Akira Costa dos; Bastos, Alessandra da Silva; Pontual, José Daniel Costa; Araújo, Cristiane Santos de; Lima, Analice dos Santos de; Martinez, Leandro do Nascimento ; Ferreira, Amália dos Santos; Aguiar, Anna Caroline Campos ; Teles, Carolina Bioni Garcia ; Guido, Rafael Victorio Carvalho ; Santana, Rosa Amélia Gonçalves; Lopes, Stefanie Costa Pinto ; Medeiros, Jansen Fernandes de ; Rizopoulos, Zaira; Vinetz, Joseph Michael; Campo, Brice; Lacerda, Marcus Vinícius Guimarães de ; Araújo, Maisa da Silva
Source: Scientific Reports. Unidades: IFSC, FSP
Subjects: PLASMODIUM, ANOPHELES, PLANEJAMENTO DE FÁRMACOS
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ABNT
ANDRADE, Alice Oliveira et al. Optimization of Plasmodium vivax infection of colonized Amazonian Anopheles darlingi. Scientific Reports, v. 13, p. 18207-1-18207-11 + supplementary information, 2023Tradução . . Disponível em: https://doi.org/10.1038/s41598-023-44556-y. Acesso em: 08 nov. 2025.
APA
Andrade, A. O., Santos, N. A. C. dos, Bastos, A. da S., Pontual, J. D. C., Araújo, C. S. de, Lima, A. dos S. de, et al. (2023). Optimization of Plasmodium vivax infection of colonized Amazonian Anopheles darlingi. Scientific Reports, 13, 18207-1-18207-11 + supplementary information. doi:10.1038/s41598-023-44556-y
NLM
Andrade AO, Santos NAC dos, Bastos A da S, Pontual JDC, Araújo CS de, Lima A dos S de, Martinez L do N, Ferreira A dos S, Aguiar ACC, Teles CBG, Guido RVC, Santana RAG, Lopes SCP, Medeiros JF de, Rizopoulos Z, Vinetz JM, Campo B, Lacerda MVG de, Araújo M da S. Optimization of Plasmodium vivax infection of colonized Amazonian Anopheles darlingi [Internet]. Scientific Reports. 2023 ; 13 18207-1-18207-11 + supplementary information.[citado 2025 nov. 08 ] Available from: https://doi.org/10.1038/s41598-023-44556-y
Vancouver
Andrade AO, Santos NAC dos, Bastos A da S, Pontual JDC, Araújo CS de, Lima A dos S de, Martinez L do N, Ferreira A dos S, Aguiar ACC, Teles CBG, Guido RVC, Santana RAG, Lopes SCP, Medeiros JF de, Rizopoulos Z, Vinetz JM, Campo B, Lacerda MVG de, Araújo M da S. Optimization of Plasmodium vivax infection of colonized Amazonian Anopheles darlingi [Internet]. Scientific Reports. 2023 ; 13 18207-1-18207-11 + supplementary information.[citado 2025 nov. 08 ] Available from: https://doi.org/10.1038/s41598-023-44556-y
Artigo de periodico
Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183 (2022)
Vries, Laura E. ; Aguiar, Anna Caroline Campos ; Guido, Rafael Victorio Carvalho
Source: Nature Communications. Unidade: IFSC
Subjects: PLASMODIUM FALCIPARUM, PLANEJAMENTO DE FÁRMACOS, ANTIPARASITÁRIOS, MALÁRIA
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ABNT
VRIES, Laura E. e AGUIAR, Anna Caroline Campos e GUIDO, Rafael Victorio Carvalho. Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183. Nature Communications, v. 13, p. 2158-1-2158-16, 2022Tradução . . Disponível em: https://doi.org/10.1038/s41467-022-29688-5. Acesso em: 08 nov. 2025.
APA
Vries, L. E., Aguiar, A. C. C., & Guido, R. V. C. (2022). Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183. Nature Communications, 13, 2158-1-2158-16. doi:10.1038/s41467-022-29688-5
NLM
Vries LE, Aguiar ACC, Guido RVC. Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183 [Internet]. Nature Communications. 2022 ; 13 2158-1-2158-16.[citado 2025 nov. 08 ] Available from: https://doi.org/10.1038/s41467-022-29688-5
Vancouver
Vries LE, Aguiar ACC, Guido RVC. Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183 [Internet]. Nature Communications. 2022 ; 13 2158-1-2158-16.[citado 2025 nov. 08 ] Available from: https://doi.org/10.1038/s41467-022-29688-5
Artigo de periodico
Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome (2021)
Xie, Stanley C. ; Aguiar, Anna Caroline Campos ; Guido, Rafael Victorio Carvalho
Source: Proceedings of the National Academy of Sciences of the United States of America - PNAS. Unidade: IFSC
Subjects: PLASMODIUM FALCIPARUM, PLANEJAMENTO DE FÁRMACOS, MALÁRIA, QUÍMICA MÉDICA
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ABNT
XIE, Stanley C. e AGUIAR, Anna Caroline Campos e GUIDO, Rafael Victorio Carvalho. Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome. Proceedings of the National Academy of Sciences of the United States of America - PNAS, v. 118, n. 39, p. e2107213118-1-e2107213118-9, 2021Tradução . . Disponível em: https://doi.org/10.1073/pnas.2107213118. Acesso em: 08 nov. 2025.
APA
Xie, S. C., Aguiar, A. C. C., & Guido, R. V. C. (2021). Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 118( 39), e2107213118-1-e2107213118-9. doi:10.1073/pnas.2107213118
NLM
Xie SC, Aguiar ACC, Guido RVC. Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome [Internet]. Proceedings of the National Academy of Sciences of the United States of America - PNAS. 2021 ; 118( 39): e2107213118-1-e2107213118-9.[citado 2025 nov. 08 ] Available from: https://doi.org/10.1073/pnas.2107213118
Vancouver
Xie SC, Aguiar ACC, Guido RVC. Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome [Internet]. Proceedings of the National Academy of Sciences of the United States of America - PNAS. 2021 ; 118( 39): e2107213118-1-e2107213118-9.[citado 2025 nov. 08 ] Available from: https://doi.org/10.1073/pnas.2107213118
Artigo de periodico
Repositioning and characterization of 1‑(Pyridin-4-yl)pyrrolidin-2- one derivatives as plasmodium cytoplasmic prolyl-tRNA synthetase inhibitors (2021)
Okaniwa, Masanori; Aguiar, Anna Caroline Campos; Guido, Rafael Victorio Carvalho
Source: ACS Infectious Diseases. Unidade: IFSC
Subjects: PLASMODIUM, MALÁRIA, ANTIMALÁRICOS, ANTIPARASITÁRIOS
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ABNT
OKANIWA, Masanori e AGUIAR, Anna Caroline Campos e GUIDO, Rafael Victorio Carvalho. Repositioning and characterization of 1‑(Pyridin-4-yl)pyrrolidin-2- one derivatives as plasmodium cytoplasmic prolyl-tRNA synthetase inhibitors. ACS Infectious Diseases, v. 7, n. 6, p. 1680-1689, 2021Tradução . . Disponível em: https://doi.org/10.1021/acsinfecdis.1c00020. Acesso em: 08 nov. 2025.
APA
Okaniwa, M., Aguiar, A. C. C., & Guido, R. V. C. (2021). Repositioning and characterization of 1‑(Pyridin-4-yl)pyrrolidin-2- one derivatives as plasmodium cytoplasmic prolyl-tRNA synthetase inhibitors. ACS Infectious Diseases, 7( 6), 1680-1689. doi:10.1021/acsinfecdis.1c00020
NLM
Okaniwa M, Aguiar ACC, Guido RVC. Repositioning and characterization of 1‑(Pyridin-4-yl)pyrrolidin-2- one derivatives as plasmodium cytoplasmic prolyl-tRNA synthetase inhibitors [Internet]. ACS Infectious Diseases. 2021 ; 7( 6): 1680-1689.[citado 2025 nov. 08 ] Available from: https://doi.org/10.1021/acsinfecdis.1c00020
Vancouver
Okaniwa M, Aguiar ACC, Guido RVC. Repositioning and characterization of 1‑(Pyridin-4-yl)pyrrolidin-2- one derivatives as plasmodium cytoplasmic prolyl-tRNA synthetase inhibitors [Internet]. ACS Infectious Diseases. 2021 ; 7( 6): 1680-1689.[citado 2025 nov. 08 ] Available from: https://doi.org/10.1021/acsinfecdis.1c00020

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